Results 31 to 40 of about 3,502,715 (318)

Enabling and hindering aspects of the i²TransHealth e-health intervention for transgender and gender diverse people in Germany: a qualitative process evaluation

BMC Health Services Research
Background Transgender and gender diverse (TGD) people in remote areas face structural barriers to accessing gender-affirming, interdisciplinary healthcare. These include limited specialised care, a shortage of TGD-informed healthcare professionals, long
Franziska Schmidt, Janis Renner, Samantha-Insine Schröder, Lea Pregartbauer, Arne Dekker, Timo O. Nieder   +5 more
doaj   +1 more source

Sex Determination: Sex on the Brain? [PDF]

Current Biology, 2003
Five newly identified sex-biased transcripts in Drosophila are full of surprises: although they are found in fly heads, and manipulating two of them affects mating behaviors, their genes are expressed sex-specifically in non-neural tissues. The way these genes are regulated suggests new complexities in the sex determination pathway.
openaire   +2 more sources

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Child sex tourism – prevalence of and risk factors for its use in a German community sample

BMC Public Health, 2017
Background To investigate the prevalence of child sex tourism (CST) in a large German community sample, and to compare those who made use of CST with other child sexual abusers regarding established characteristics and risk factors for child sexual abuse.
Thula Koops, Daniel Turner, Janina Neutze, Peer Briken   +3 more
doaj   +1 more source

Conflict over condition-dependent sex allocation can lead to mixed sex-determination systems [PDF]

, 2014
Theory suggests that genetic conflicts drive turnovers between sex-determining mechanisms, yet these studies only apply to cases where sex allocation is independent of environment or condition.
Kuijper, B, Pen, Ido, Pen, I, Kuijper, Bram   +3 more
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Sex and gender correlates of sexually polymorphic cognition

Biology of Sex Differences
Background Sexually polymorphic cognition (SPC) results from the interaction between biological (birth-assigned sex (BAS), sex hormones) and socio-cultural (gender identity, gender roles, sexual orientation) factors.
Louis Cartier, Mina Guérin, Fanny Saulnier, Ioana Cotocea, Amine Mohammedi, Fadila Moussaoui, Sarah Kheloui, Robert-Paul Juster   +7 more
doaj   +1 more source

Ligand-independent androgen receptors promote ovarian teratocarcinoma cell growth by stimulating self-renewal of cancer stem/progenitor cells

Stem Cell Research, 2014
Background: Ovarian teratocarcinoma (OVTC) arises from germ cells and contains a high percentage of cancer stem/progenitor cells (CSPCs), which promote cancer development through their ability to self-renew.
Wei-Min Chung, Wei-Chun Chang, Lumin Chen, Tze-Yi Lin, Liang-Chi Chen, Yao-Ching Hung, Wen-Lung Ma   +6 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source