Results 41 to 50 of about 4,124,044 (305)

Sex and gender correlates of sexually polymorphic cognition

Biology of Sex Differences
Background Sexually polymorphic cognition (SPC) results from the interaction between biological (birth-assigned sex (BAS), sex hormones) and socio-cultural (gender identity, gender roles, sexual orientation) factors.
Louis Cartier, Mina Guérin, Fanny Saulnier, Ioana Cotocea, Amine Mohammedi, Fadila Moussaoui, Sarah Kheloui, Robert-Paul Juster   +7 more
doaj   +1 more source

Ligand-independent androgen receptors promote ovarian teratocarcinoma cell growth by stimulating self-renewal of cancer stem/progenitor cells

Stem Cell Research, 2014
Background: Ovarian teratocarcinoma (OVTC) arises from germ cells and contains a high percentage of cancer stem/progenitor cells (CSPCs), which promote cancer development through their ability to self-renew.
Wei-Min Chung, Wei-Chun Chang, Lumin Chen, Tze-Yi Lin, Liang-Chi Chen, Yao-Ching Hung, Wen-Lung Ma   +6 more
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes

Nature Communications, 2020
If left unrepaired, meiotic DSBs are toxic to mammalian cells, thus oocytes in which DSBs persist are eliminated by the DNA-damage checkpoint. Here the authors provide insights into the roles of PUMA, NOXA and BAX during DNA damage checkpoint that ...
Elias ElInati, Agata P. Zielinska, Afshan McCarthy, Nada Kubikova, Valdone Maciulyte, Shantha Mahadevaiah, Mahesh N. Sangrithi, Obah Ojarikre, Dagan Wells, Kathy K. Niakan, Melina Schuh, James M. A. Turner   +11 more
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

A role for TRPC3 in mammalian testis development

Frontiers in Cell and Developmental Biology
SOX9 is a key transcription factor for testis determination and development. Mutations in and around the SOX9 gene contribute to Differences/Disorders of Sex Development (DSD).
Zhenhua Ming, Zhenhua Ming, Stefan Bagheri-Fam, Emily R. Frost, Janelle M. Ryan, Janelle M. Ryan, Brittany Vining, Brittany Vining, Vincent R. Harley, Vincent R. Harley   +9 more
doaj   +1 more source

Sex dimorphism of weight and length at birth: evidence based on disorders of sex development

Annals of Human Biology, 2022
Background Males have higher weight and length at birth than females. Aim To verify the influence of the Y chromosome and the action of intrauterine androgens on weight and length at birth of children with Disorders of Sex Development (DSD). Subjects and
D.S.R. Amais, T.E.R. da Silva, B.A. Barros, J.G.R. de Andrade, S.H.V. de Lemos-Marini, M.P. de Mello, A.P. Marques-de-Faria, T.N. Mazzola, M.S. Guaragna, H. Fabbri-Scallet, T.A.P. Vieira, N.L. Viguetti-Campos, A.M. Morcillo, O. Hiort, A.T. Maciel-Guerra, G. Guerra-Junior   +15 more
doaj   +1 more source

Cape Town talks about sex workers [PDF]

, 2000
On Monday 25 September,, as- part of the One City Festival, the Black Arts Collective hosted a debate about sex work. Natasha from SWEAT spoke about the why the government should decriminalize sex work.
Sex Workers’ Education & Advocacy Taskforce (SWEAT)
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