Results 61 to 70 of about 7,818,257 (391)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A role for TRPC3 in mammalian testis development

Frontiers in Cell and Developmental Biology
SOX9 is a key transcription factor for testis determination and development. Mutations in and around the SOX9 gene contribute to Differences/Disorders of Sex Development (DSD).
Zhenhua Ming, Zhenhua Ming, Stefan Bagheri-Fam, Emily R. Frost, Janelle M. Ryan, Janelle M. Ryan, Brittany Vining, Brittany Vining, Vincent R. Harley, Vincent R. Harley   +9 more
doaj   +1 more source

Access to infertility investigations and treatment for HIV+ people: a survey of Australian infertility clinics

Australian and New Zealand Journal of Public Health, 2004
Objective:To examine the availability in Australia of investigations and treatment of infertility for people infected with HIV. Methods:The study was a questionnaire survey of all identified Australian IVF clinics undertaken in 2002.
Marian Pitts, Penelope Shields
doaj   +1 more source

Differentiating Sex from Sex: The Male Irresistible Impulse [PDF]

, 1983
The courts have not wholeheartedly embraced the idea of equality of the sexes, and therefore do not attack sex discrimination with the same vigor as they attack racism.
Aiken, Jane H.
core   +1 more source

Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus

Endocrine reviews, 2016
The steep rise of type 2 diabetes mellitus (T2DM) and associated complications go along with mounting evidence of clinically important sex and gender differences.
A. Kautzky-Willer, J. Harreiter, G. Pacini   +2 more
semanticscholar   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

The interplay of aggression and psychopathy in a correctional treatment setting

European Psychiatry
Introduction Aggression is a relevant risk factor for criminal behavior. Psychopathy is known to correlate with a higher risk for violent offenses and research suggests that successful therapy of psychopathy is complicated.
A. Voulgaris, P. Briken, E. Stück
doaj   +1 more source

More than a virus: a qualitative study of the social implications of hepatitis B infection in China

International Journal for Equity in Health, 2017
Background China has the largest absolute number of people living with hepatitis B with up to 300,000 people estimated to die each year from hepatitis B related diseases.
J. Wallace, M. Pitts, C. Liu, V. Lin, B. Hajarizadeh, J. Richmond, S. Locarnini   +6 more
doaj   +1 more source

Aspects of Sex Differences: Social Intelligence vs. Creative Intelligence [PDF]

, 2017
In this article, we argue that there is an essential difference between social intelligence and creative intelligence, and that they have their foundation in human sexuality.
Fellmann, Ferdinand, Redolfi Widmann, Esther   +1 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source