Results 71 to 80 of about 4,114,102 (347)
An elevated plus-maze in mixed reality for studying human anxiety-related behavior
BMC Biology, 2017 Background A dearth of laboratory tests to study actual human approach-avoidance behavior has complicated translational research on anxiety. The elevated plus-maze (EPM) is the gold standard to assess approach-avoidance behavior in rodents. Methods Here,
Sarah V. Biedermann +10 more
doaj +1 more source
Sex differences in metabolic regulation and diabetes susceptibility
Diabetologia, 2019 Gender and biological sex impact the pathogenesis of numerous diseases, including metabolic disorders such as diabetes. In most parts of the world, diabetes is more prevalent in men than in women, especially in middle-aged populations. In line with this,
Blandine Tramunt +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
International Journal of Endocrinology, 2016 Objective. To evaluate diagnosis, age of referral, karyotype, and sex of rearing of cases with disorders of sex development (DSD) with ambiguous genitalia. Methods. Retrospective study during 23 years at outpatient clinic of a referral center.
Georgette Beatriz De Paula +21 more
doaj +1 more source
Hepatology, 2019 Despite tremendous research advancements in nonalcoholic fatty liver disease (NAFLD), our understanding of sex differences in NAFLD remains insufficient.
A. Lonardo +7 more
semanticscholar +1 more source
Metabolism and sex, sex and metabolism [PDF]
Urologie pro praxi, 2017 Erektilni dysfunkce je poměrně castým zdravotnim problemem, v Ceske republice trpi ve věku 35–65 let různým stupněm tohoto onemocněni vice než polovina mužů. Přiciny erektilni dysfunkce mohou být psychogenni a organicke, mezi organicke pak patři anatomicke, neurogenni, hormonalni a vaskularni.
openaire +2 more sources
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
New approaches and established models for scaling up sex- and gender-sensitive medicine teaching
npj Women's HealthTeaching sex and gender-sensitive medicine (SGSM) can enhance the quality of medical care for people of all genders. However, the available literature about the implementation of SGSM in medical education is limited, and theoretical models are lacking ...
Laura Wortmann, Sabine Oertelt-Prigione
doaj +1 more source