Results 71 to 80 of about 5,868,024 (344)
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
The interplay of aggression and psychopathy in a correctional treatment setting
European PsychiatryIntroduction Aggression is a relevant risk factor for criminal behavior. Psychopathy is known to correlate with a higher risk for violent offenses and research suggests that successful therapy of psychopathy is complicated.
A. Voulgaris, P. Briken, E. Stück
doaj +1 more source
Australian and New Zealand Journal of Public Health, 2017 Objective: Rates of sexually transmitted infections (STIs) are rising among older Australians. We conducted a large survey of older people's knowledge of STIs and safer sexual practices.
Anthony Lyons +8 more
doaj +1 more source
Premature ejaculation - current concepts in the management: A narrative review
International Journal of Reproductive BioMedicine, 2021 Premature ejaculation (PE; early ejaculation or rapid ejaculation) is a common sexual problem affecting about 20-30% of men in the sexually active age group. PE can be of four types: Primary, secondary, natural variable, and subjective PE.
Arkiath Veettil Raveendran +1 more
doaj +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
International Journal of Endocrinology, 2016 Objective. To evaluate diagnosis, age of referral, karyotype, and sex of rearing of cases with disorders of sex development (DSD) with ambiguous genitalia. Methods. Retrospective study during 23 years at outpatient clinic of a referral center.
Georgette Beatriz De Paula +21 more
doaj +1 more source
Intimacy, pleasure and the men who pay for sex [PDF]
, 2008 About the repository: This book brings together chapters by academics, researchers and practitioners to analyse how crimes such as sex work, domestic violence and rape and sexual assault have risen up the Government agenda in recent years.
Earle, Sarah, Sharp, Keith
core
Metabolism and sex, sex and metabolism [PDF]
Urologie pro praxi, 2017 Erektilni dysfunkce je poměrně castým zdravotnim problemem, v Ceske republice trpi ve věku 35–65 let různým stupněm tohoto onemocněni vice než polovina mužů. Přiciny erektilni dysfunkce mohou být psychogenni a organicke, mezi organicke pak patři anatomicke, neurogenni, hormonalni a vaskularni.
openaire +2 more sources