Results 81 to 90 of about 4,114,102 (347)

Gender‐specific health implications of minority stress among lesbians and gay men

open access: yesAustralian and New Zealand Journal of Public Health, 2016
Objectives: Lesbians and gay men are exposed to unique minority stressors. We examined the health implications of one type of distal minority stressor (victimisation) and one type of proximal minority stressor (sexual identity concealment due to ...
Emily Bariola   +2 more
doaj   +1 more source

Sex Differences in Gut Microbiota

open access: yesThe World Journal of Men's Health, 2019
Humans carry numerous symbiotic microorganisms in their body, most of which are present in the gut. Although recent technological advances have produced extensive research data on gut microbiota, there are various confounding factors (e.g., diet, race ...
Y. Kim, T. Unno, B. Kim, Mi-sung Park
semanticscholar   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Implementation of hepatitis C cure in Australia: one year on

open access: yesJournal of Virus Eradication, 2018
Objectives: Direct-acting antivirals (DAAs) for the treatment of hepatitis C (HCV) became universally available in Australia in March 2016, with an aim to achieve HCV elimination. Fourteen per cent of Australians with HCV have initiated treatment.
Jacqueline A. Richmond, Jack Wallace
doaj   +1 more source

Sex and the MHC [PDF]

open access: yesDevelopmental Cell, 2003
Major histocompatibility complex class Ib molecules may play a surprising role in pheromone detection in mammals.
openaire   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Sex differences in heart failure.

open access: yesEuropean Heart Journal, 2019
The overall lifetime risk of heart failure (HF) is similar between men and women, however, there are marked sex differences in the landscape of this condition that are both important and under-recognized.
C. Lam   +9 more
semanticscholar   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga   +8 more
wiley   +1 more source

GnRH analogs as a monotherapy in transgender and gender-diverse adolescents: clinical insights from a single-center study

open access: yesEndocrine Connections
Background: Gonadotropin-releasing hormone agonists (GnRHas) are widely used in the treatment of transgender and gender-diverse adolescents to prevent the development of undesired physical changes.
Fleur A H Lahaije   +4 more
doaj   +1 more source

Sex Hormones in Acquired Immunity and Autoimmune Disease

open access: yesFrontiers in Immunology, 2018
Women have stronger immune responses to infections and vaccination than men. Paradoxically, the stronger immune response comes at a steep price, which is the high incidence of autoimmune diseases in women. The reasons why women have stronger immunity and
Vaishali R. Moulton
semanticscholar   +1 more source

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