Results 61 to 70 of about 1,500,141 (319)
Molecular Oncology, EarlyView.Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang +10 more
wiley +1 more source
Commercial human pulmonary artery endothelial cells have in‐vitro behavior that varies by sex
Pulmonary Circulation, 2022 It is unknown whether biological sex influences phenotypes of commercially available human pulmonary artery endothelial cells (HPAECs). Ten lots of commercial HPAECs were used (Lonza Biologics; PromoCell).
Katherine Cox‐Flaherty +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa +13 more
wiley +1 more source
Reviews in Cardiovascular Medicine, 2023 Background: To assess whether there are differences in common postoperative complications and survival between men and women after transcatheter aortic valve implantation.
Zekun Lang +7 more
doaj +1 more source
SW Sextantis stars: the dominant population of CVs with orbital periods between 3-4 hours [PDF]
Mon.Not.Roy.Astron.Soc.377:1747-1762,2007, 2007 [Abridged] We present time-series optical photometry of five new CVs identified by the Hamburg Quasar Survey. The eclipses observed in HS 0129+2933, HS 0220+0603, and HS 0455+8315 provided very accurate orbital periods of 3.35129827(65), 3.58098501(34), and 3.56937674(26) h, respectively.
arxiv +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Diagnostics, 2021 The performance of postural control is believed to be linked to how children use available sensory stimuli to produce adequate muscular activation.
Jesús García-Liñeira +3 more
doaj +1 more source
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
Gender difference in the association between brachial-ankle pulse wave velocity and cardiovascular risk scores [PDF]
The Korean Journal of Internal Medicine, 2019 Background/Aims Although brachial-ankle pulse wave velocity (baPWV) has been validated as a novel method to predict the cardiovascular risk in general population, the relevance of baPWV to the traditional risk scores has not been clearly revealed.
Tae-Min Rhee +8 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background We describe sex‐differential disease patterns and outcomes of >20.6 million cardiovascular emergency department encounters in the United States.
Zahra Raisi‐Estabragh +11 more
doaj +1 more source