Results 91 to 100 of about 60,046 (266)
Animal Research and One Health, EarlyView.The experimental framework of the study encompasses sample collection, single‐cell data analysis, and experimental validation. Abstract Understanding differences in chromatin state and changes in gene regulatory landscape of placode (Pc) and dermal condensate are crucial for decoding hair follicle (HF) morphogenesis programs.
Fang Li +5 more
wiley +1 more source
Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2.
PLoS Genetics, 2020 Sex differences in the incidence and progression of many liver diseases, including liver fibrosis and hepatocellular carcinoma, are associated with sex-biased hepatic expression of hundreds of genes.
Dana Lau-Corona +3 more
doaj +1 more source
Autism Research, EarlyView.ABSTRACT Among autistic individuals, a subphenotype of disproportionate megalencephaly (ASD‐DM) seen at three years of age is associated with co‐occurring intellectual disability and poorer prognoses later in life. However, many of the genes contributing to ASD‐DM have yet to be delineated. In this study, we identified additional ASD‐DM candidate genes
Sierra S. Nishizaki +10 more
wiley +1 more source
Chromatin Folding in Relation to Human Genome Function [PDF]
arXiv, 2007 Three-dimensional (3D) chromatin structure is closely related to genome function, in particular transcription. However, the folding path of the chromatin fiber in the interphase nucleus is unknown. Here, we systematically measured the 3D physical distance between pairwise labeled genomic positions in gene-dense, highly transcribed domains and gene-poor
arxiv
LARP7 is required for sex chromosome silencing during meiosis in mice.
PLoS ONEMeiotic sex chromosome inactivation (MSCI) is an essential event in meiotic progression in mammalian spermatogenesis. We found that La Ribonucleoprotein 7 (LARP7) is involved in MSCI. LARP7 plays a role in fetal germ cells to promote their proliferation,
Yukiko Tando +6 more
doaj +1 more source
Inorganic Metal Nanoparticles in Reproductive Biology: Applications, Toxicities and Future Prospects
ChemPlusChem, EarlyView.Metal nanoparticles (MNPs) have shown great promise in the livestock industry such as semen collection, nano‐purification, cryopreservation, sex sorting, bioimaging, drug and gene delivery. However, reproductive toxicity induced by MNP has adverse effects on various sexual functions including poor sperm parameters, testicular damage, ovary injury, and ...
Sangita Kundu +3 more
wiley +1 more source
Diagnostic Cytopathology, EarlyView.ABSTRACT Angiosarcoma with malignant effusion is an uncommon yet clinically aggressive presentation, which poses as a diagnostic pitfall with its overlapping cytomorphologic features with metastatic adenocarcinoma. In this article, two cases reported in the literature were reviewed for cytology, immunocytochemistry, and clinical course.
Jamie C. Y. Lam +3 more
wiley +1 more source
Genetic proof of chromatin diminution under mitotic agamospermy [PDF]
arXiv, 2013 The previously published data are examined on the base of the hypothesis about existence of differential polyteny of chromosomes and excess chromatin diminution during the first stages of embryogenesis. It has been concluded that available data provide the genetic proof that chromatin diminution is one of the mechanisms underlying the origin of ...
arxiv
Asian Pacific Journal of Reproduction, 2018 Objective: To evaluate the effect of graded doses of acetylsalicylic acid (ASA) on sperm chromatin integrity and sex hormones in the adult male mouse. Methods: Forty-nine male adult mice were divided into seven groups.
Farzaneh Mahmoudi-Lafout +1 more
doaj +1 more source
European Journal of Heart Failure, EarlyView.Association of clonal haematopoiesis with heart failure incidence and outcomes: A systematic review and meta‐analysis. Clonal haematopoiesis and heart failure: a meta‐analysis. CH, clonal haematopoiesis; CI, confidence interval; HF, heart failure. [Correction added on 15 March 2025, after first online publication: The graphical image was corrected in ...
Paschalis Karakasis +8 more
wiley +1 more source