Results 101 to 110 of about 60,046 (266)
A polycomb group protein is retained at specific sites on chromatin in mitosis.
PLoS Genetics, 2012 Epigenetic regulation of gene expression, including by Polycomb Group (PcG) proteins, may depend on heritable chromatin states, but how these states can be propagated through mitosis is unclear.
Nicole E Follmer +2 more
doaj +1 more source
Properties of Chromatin in Human Cells as Characteristics of the State of Human Organism: A Review [PDF]
Adv Complement Alt Med. 1(1). ACAM.000505. 2018.
http://crimsonpublishers.com/acam/volume1-issue1-acam.php, 2018 The state of chromatin in individual cells is directly related to the state of the whole organism and may be used for assessment of the state of the whole organism. Many hereditary diseases are connected with chromatin rearrangements. Chromatin distribution in cell nucleus is an important characteristic which may be applied for determination of disease
arxiv
PLoS ONE, 2014 In rodent female mammals, there are two forms of X-inactivation - imprinted and random which take place in extraembryonic and embryonic tissues, respectively.
Evgeniya A Vaskova +7 more
doaj +1 more source
Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity [PDF]
arXiv, 2015 Network analysis is a powerful way of modeling chromatin interactions. Assortativity is a network property used in social sciences to identify factors affecting how people establish social ties. We propose a new approach, using chromatin assortativity to integrate the epigenomic landscape of a specific cell type with its chromatin interaction network ...
arxiv
Glia, EarlyView.Zdhhc9 ablation grossly changes gene expression and myelin protein levels in CNS WM. Zdhhc9 is important for the establishment of mature oligodendrocyte subtypes. Zdhhc9 is important for axon myelination and the maintenance of myelin integrity. ABSTRACT Two percent of patients with X‐linked intellectual disability (XLID) exhibit loss‐of‐function ...
Rocio B. White +9 more
wiley +1 more source
Anti-chromatin antibodies in juvenile rheumatoid arthritis
Reumatismo, 2003 Objective: to evaluate the prevalence and clinical significance of anti-chromatin antibodies (Abs) in juvenile rheumatoid arthritis (JRA). Methods: IgG anti-chromatin Abs were detected by an enzyme-linked immunosorbent assay (ELISA), in sera of 94 ...
F. Ingegnoli +6 more
doaj +1 more source
Loss of SMARCB1 evokes targetable epigenetic vulnerabilities in epithelioid sarcoma
Cancer Communications, EarlyView.
Jia Xiang Jin +12 more
wiley +1 more source
Environment, lifestyle, and cancer in women
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Environmental and lifestyle factors significantly contribute to gynecological cancers. The risk of ovarian cancer, one the most lethal gynecological cancer, is associated with obesity, poor dietary habits, and environmental pollutants, exacerbating hormonal imbalances, inflammation, and oxidative stress.
Sara Farina +3 more
wiley +1 more source
Century-old chromatin architecture revealed in formalin-fixed vertebrates
Nature CommunicationsGene expression is regulated by changes in chromatin architecture intrinsic to cellular differentiation and as an active response to environmental stimuli.
Erin E. Hahn +7 more
doaj +1 more source
The physics of chromatin [PDF]
arXiv, 2003 Recent progress has been made in the understanding of the physical properties of chromatin -- the dense complex of DNA and histone proteins that occupies the nuclei of plant and animal cells. Here I will focus on the two lowest levels of the hierarchy of DNA folding into the chromatin complex: (i) the nucleosome, the chromatin repeating unit consisting
arxiv