Results 191 to 200 of about 123,835 (338)

Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder. [PDF]

open access: yesNat Commun
Green NC   +20 more
europepmc   +1 more source

Brain DNA Methylation Atlas of AppNL‐G‐F Alzheimer's Disease Model Mice Across Age and Region Reveals Choline‐Induced Resilience

open access: yesAging Cell, EarlyView.
Brain DNA methylation drives abnormal gene expression in AppNL‐G‐F mice. Perinatal choline supplementation may promote resilience to synaptic dysfunction through modulation of DNA methylation. ABSTRACT Alzheimer's disease (AD) is the most common type of dementia.
Andre Krunic   +7 more
wiley   +1 more source

Sex differences in brain cell-type specific chromatin accessibility in schizophrenia [PDF]

open access: green
Panos Roussos   +5 more
openalex   +2 more sources

Contribution of Sex-Biased Expressed Genes in Osteoarthritis. [PDF]

open access: yesSmart Med
Wang C   +7 more
europepmc   +1 more source

Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy

open access: yesAging Cell, EarlyView.
Post‐menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre‐menopausal (< 40 years) females. Hormone Replacement Therapy (HRT) use in menopausal females (44–60 years) decreases the frequency of inflammatory monocytes and improves phagocytosis as compared to age ...
R. P. H. De Maeyer   +13 more
wiley   +1 more source

Deciphering meiotic chromatin organization by SYCP3. [PDF]

open access: yesNucleic Acids Res
Guo S   +12 more
europepmc   +1 more source

Aging Increases Short, Inverted Repeat‐Mediated Genomic Instability In Vivo

open access: yesAging Cell, EarlyView.
Aging amplifies the mutagenic potential of short, inverted repeats in mice. The increase in point mutations in the spleen and large deletions in the brain with age highlights distinct pathways across proliferative and post‐mitotic tissues. ABSTRACT Genomic instability is a hallmark of aging and cancer.
Pooja Mandke   +3 more
wiley   +1 more source

Genome-wide association study of chlamydia reinfection in African American women. [PDF]

open access: yesFront Immunol
Tiwari HK   +7 more
europepmc   +1 more source

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