Results 201 to 210 of about 123,835 (338)

Caloric Restriction Reprograms Adipose Tissues in Rhesus Monkeys

Aging Cell, EarlyView.
Here we show shared and depot‐specific adaptations to life‐long CR in subcutaneous and visceral adipose depots from advanced‐age male rhesus monkeys. Transcriptomics reveal differences between the depots, as well as shared and distinct CR‐responsive pathways.
Josef P. Clark, Timothy W. Rhoads, Sean J. McIlwain, Michael A. Polewski, Derek M. Pavelec, Ricki J. Colman, Rozalyn M. Anderson   +6 more
wiley   +1 more source

Engineering HMGB1-derived Peptides to Unravel Sex-Specific Mechanisms in Pulmonary Arterial Hypertension. [PDF]

Am J Respir Cell Mol Biol
Zheng Q, Dai Z.
europepmc   +1 more source

Occurrence of Sex Chromatin in the Basal Cells of the Epidermis and in Basal Cell Carcinomata [PDF]

, 1958
David J. B. Ashley
openalex   +1 more source

Canagliflozin Reprograms the Aging Hippocampus in Genetically Diverse UM‐HET3 Mice and Attenuates Alzheimer's‐Like Pathology

Aging Cell, EarlyView.
Canagliflozin enhances hippocampal function, reduces Aβ pathology, and improves cognitive function in male mice, while females show limited benefits, revealing sex‐specific neuroprotective responses across aging and Alzheimer's models. ABSTRACT Aging is the strongest risk factor for cognitive decline and Alzheimer's disease (AD), yet the mechanisms ...
Hashan Jayarathne, Dulmalika Herath Manchanayake, Ryan Sullivan, Nina Chimienti, Omar Kadri, Katherine Gurdziel, Seongho Kim, Hyejeong Jang, Brett C. Ginsburg, Richard A. Miller, Shoshana Yakar, Marianna Sadagurski   +11 more
wiley   +1 more source

Genotype‐by‐sex interaction analyses for alcohol use disorder across biobanks

Alcohol, Clinical and Experimental Research, EarlyView.
Alcohol use disorder (AUD) differs by sex in prevalence and clinical features, yet genetic studies on these differences are limited. Using genome‐wide genotype‐by‐sex interaction analyses in over 1 million participants from the Million Veteran Program and UK Biobank, we identified four significant loci with sex‐specific effects on AUD risk.
Hang Zhou, Lu Wang, Zhongzheng Mao, P. J. Michael Deans, Rachel L. Kember, Qingyu Chen, Yasmin Zakiniaeiz, Robert Kohler, MacKenzie R. Peltier, Terril L. Verplaetse, VA Million Veteran Program, Marc N. Potenza, Kristen J. Brennand, Amy C. Justice, Henry R. Kranzler, Joel Gelernter, Sherry A. McKee, Sumitra Muralidhar, Jennifer Moser, Jennifer E. Deen, Philip S. Tsao, Sumitra Muralidhar, J. Michael Gaziano, Elizabeth Hauser, Amy Kilbourne, Michael Matheny, Dave Oslin, Deepak Voora, J. Michael Gaziano, Philip S. Tsao, Jessica V. Brewer, Mary T. Brophy, Mary T. Brophy, Lori Churby, Scott L. DuVall, Saiju Pyarajan, Robert Ringer, Luis E. Selva, Shahpoor (Alex) Shayan, Brady Stephens, Stacey B. Whitbourne, Themistocles L. Assimes, Adriana Hung, Henry Kranzler   +43 more
wiley   +1 more source

Multigenerational temperature effects on paternal epigenetic inheritance in European sea bass. [PDF]

Epigenetics Chromatin
Sánchez-Baizán N, Allal F, Vandeputte M, Piferrer F.   +3 more
europepmc   +1 more source

Analysis of genes and chromosomes by non-isotopic in situ hybridization [PDF]

, 1991
Boyle, A. L., Cremer, Thomas, Lichter, Peter, Ward, D. C.   +3 more
core   +1 more source

Genome‐Wide Blood DNA Methylation Profiling in Birch Pollen Allergic Patients Undergoing Allergen‐Specific Immunotherapy

Allergy, EarlyView.
Whole genome‐wide DNA methylation analysis of whole blood of patients undergoing 6 months of birch pollen subcutaneous allergen immunotherapy revealed epigenetic changes linked to allergen immunotherapy. Birch pollen AIT decreases methylation in HLA genes and induces methylation in genes associated with Th2 and TGF‐β pathways, increases CD8+ T cell ...
Angelika Lahnsteiner, Victoria Ellmer, Mengzhen Hao, Line Kring Tannert, Serge A. Versteeg, Carsten Bindslev‐Jensen, Ronald van Ree, Angela Risch, Lorenz Aglas   +8 more
wiley   +1 more source

Sex Chromatin in Prednisone-treated Children [PDF]

, 1966
K. Taranath Shetty, Nijee Sharma, K. M. Wahal   +2 more
openalex   +1 more source

Geminin deficiency enhances survival in a murine medulloblastoma model by inducing apoptosis of preneoplastic granule neuron precursors [PDF]

, 2017
Dearborn, Joshua, Kroll, Kristen L, Lewis, Emily M, Patterson, Ethan, Rubin, Joshua B, Sankar, Savita, Tong, Caili, Waller, Laura E, Wozniak, David   +8 more
core   +2 more sources