Results 201 to 210 of about 128,998 (343)

Deciphering the gonadal cell atlas of Monopterus albus and cell fate during sex reversal based on single-cell RNA sequencing. [PDF]

open access: yesStem Cell Res Ther
Yi L   +11 more
europepmc   +1 more source

Hypomethylating agents in vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS): A systematic review

open access: yesBritish Journal of Haematology, EarlyView.
Summary VEXAS syndrome (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) is an X‐linked, systemic, haemato‐inflammatory syndrome caused by somatic mutations in the UBA1 gene. No standardized treatment guidelines exist, but evidence is emerging that treatment with hypomethylating agents (HMAs) can induce improvement of the inflammatory symptoms,
Fieke W. Hoff   +3 more
wiley   +1 more source

Distinct transcriptomic and epigenomic responses of mature oligodendrocytes during disease progression in a mouse model of multiple sclerosis. [PDF]

open access: yesNat Neurosci
Zheng C   +10 more
europepmc   +1 more source

3D imaging of neuronal inclusions and protein aggregates in human neurodegeneration by multiscale x‐ray phase‐contrast tomography

open access: yesBrain Pathology, EarlyView.
x‐ray phase‐contrast tomography enabled three‐dimensional, label‐free visualization and quantification of protein aggregates in neurodegenerative diseases with isotropic submicrometer resolution. The study revealed distinct electron density patterns in Lewy bodies, Hirano bodies, granulovacuolar degeneration, and amyloid plaques, highlighting their ...
Jonas Franz   +9 more
wiley   +1 more source

Maternal Nutrition, Toxicants, and Epigenetic Programming of Obesity Across Generations. [PDF]

open access: yesDiabetes Metab Syndr Obes
Alum EU   +5 more
europepmc   +1 more source

Malignant craniopharyngiomas: Institutional experience and literature review

open access: yesBrain Pathology, EarlyView.
We report the second case of malignant craniopharyngioma with BAP1 and TP53 mutations. A literature review identified 44 cases of malignant craniopharyngiomas with a median overall survival of 6 months. Eighteen (41%) occurred in patients without any history of radiation, suggesting that mechanisms other than radiation have contributed to their ...
Thomas J. Auen   +10 more
wiley   +1 more source

Sex chromatin and nuclear sex-specific appendages in the newborn

open access: yesThe Turkish Journal of Pediatrics, 1969
S Sakhaullah
doaj  

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