Results 201 to 210 of about 60,046 (266)

Shorter Telomeres and Faster Telomere Attrition in Individuals With Five Syndromic Forms of Intellectual Disability: A Systematic Review and Meta‐Analysis

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background People with intellectual disability suffer complex challenges due to adaptive functioning limitations, high rates of chronic diseases and shortened lifespans compared with the general population. Telomere shortening is a hallmark of ageing, and short telomeres are linked to neurological disorders.
Sarah M. Hanley, Nicola S. Schutte, Jessica Bellamy, Joshua Denham   +3 more
wiley   +1 more source

Chromosome and sex-chromatin studies of patients with hypospadias

The Turkish Journal of Pediatrics, 1969
E Tunçbilek
doaj  

Eosinophil cytolysis with or without ETosis in four cases of human gastric cancer: a comparative ultrastructural study. [PDF]

Explor Target Antitumor Ther
Caruso R, Caruso V, Rigoli L.
europepmc   +1 more source

Imaging malaria parasites across scales and time

Journal of Microscopy, EarlyView.
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley   +1 more source

The expression order determines the pioneer functions of NGN3 and NEUROD1 in pancreatic endocrine differentiation. [PDF]

Sci Adv
Yang L, Yu XX, Wang X, Jin CT, Xu CR.
europepmc   +1 more source

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

Journal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann, Sarah Hofmann, Clemens Gögele, Eva Frank, Christian Werner, Maria Kokozidou, Bernd Hoffmann, Jens Konrad, Gundula Schulze‐Tanzil   +8 more
wiley   +1 more source

The impact of sex on memory during aging and Alzheimer's disease progression: Epigenetic mechanisms. [PDF]

J Alzheimers Dis
Scheinman SB, Dong H.
europepmc   +1 more source

Metabolomics in cardiometabolic diseases: Key biomarkers and therapeutic implications for insulin resistance and diabetes

Journal of Internal Medicine, EarlyView.
Abstract Cardiometabolic diseases—including Type 2 diabetes and obesity—remain leading causes of global mortality. Recent advancements in metabolomics have facilitated the identification of metabolites that are integral to the development of insulin resistance, a characteristic feature of cardiometabolic disease. Key metabolites, such as branched‐chain
David Rizo‐Roca, John D. Henderson, Juleen R. Zierath   +2 more
wiley   +1 more source

Reshaping the chromatin landscape in HUVECs from small-for-gestational-age newborns. [PDF]

JCI Insight
Yan L, Zhou Z, Chen S, Feng X, Mao J, Luo F, Zhu J, Chen X, Hu Y, Wang Y, Wu B, Du L, Wang C, Gong L, Zhu Y.   +14 more
europepmc   +1 more source

Hybridization and gene expression: Beyond differentially expressed genes

Molecular Ecology, EarlyView.
Abstract Gene expression has a key role in reproductive isolation, and studies of hybrid gene expression have identified mechanisms causing hybrid sterility. Here, we review the evidence for altered gene expression following hybridization and outline the mechanisms shown to contribute to altered gene expression in hybrids. Transgressive gene expression,
Anna Runemark, Emily C. Moore, Erica L. Larson   +2 more
wiley   +1 more source