Results 211 to 220 of about 60,046 (266)

A genome-wide association study identifies novel genetic variants associated with neck or shoulder pain in the UK biobank (N = 430,193). [PDF]

Pain Rep
Tao Y, Pan Q, Cai T, Lu ZH, Haque M, Dottorini T, Colvin LA, Smith BH, Meng W.   +8 more
europepmc   +1 more source

Matching maternal and paternal experiences underpin molecular thermal acclimation

Molecular Ecology, EarlyView.
Abstract The environment experienced by one generation has the potential to affect the subsequent one through non‐genetic inheritance of parental effects. Since both mothers and fathers can influence their offspring, questions arise regarding how the maternal, paternal and offspring experiences integrate into the resulting phenotype.
L. C. Bonzi, J. M. Donelson, R. K. Spinks, P. L. Munday, T. Ravasi, C. Schunter   +5 more
wiley   +1 more source

Asxl1 loss in mice leads to microcephaly by regulating neural stem cell survival. [PDF]

Anim Cells Syst (Seoul)
Kim H, Kim AR, Byun S, Um SJ.
europepmc   +1 more source

Genetic Architecture of Immune Cell DNA Methylation in the Rhesus Macaque

Molecular Ecology, EarlyView.
ABSTRACT Genetic variation that impacts gene regulation, rather than protein function, can have strong effects on trait variation both within and between species. Epigenetic mechanisms, such as DNA methylation, are often an important intermediate link between genotype and phenotype, yet genetic effects on DNA methylation remain understudied in natural ...
Christina E. Costa, Marina M. Watowich, Elisabeth A. Goldman, Kirstin N. Sterner, Josue E. Negron‐Del Valle, Daniel Phillips, Cayo Biobank Research Unit, Michael L. Platt, Michael J. Montague, Lauren J. N. Brent, James P. Higham, Noah Snyder‐Mackler, Amanda J. Lea   +12 more
wiley   +1 more source

Contrasting genetic predisposition and diagnosis in psychiatric disorders: A multi-omic single-nucleus analysis of the human OFC. [PDF]

Sci Adv
Gerstner N, Fröhlich AS, Matosin N, Gagliardi M, Cruceanu C, Ködel M, Rex-Haffner M, Tu X, Mostafavi S, Ziller MJ, Binder EB, Knauer-Arloth J.   +11 more
europepmc   +1 more source

The Evolution of Locally Adaptive Chromosome Inversions in Mimulus guttatus

Molecular Ecology, EarlyView.
ABSTRACT Chromosomal inversion polymorphisms are ubiquitous across the diversity of diploid organisms and play a significant role in the evolution of adaptations in those species. Inversions are thought to operate as supergenes by trapping adaptive alleles at multiple linked loci through the suppression of recombination. While there is now considerable
Leslie M. Kollar, Lauren E. Stanley, Sunil K. Kenchanmane Raju, David B. Lowry, Chad E. Niederhuth   +4 more
wiley   +1 more source

Lysine crotonylation in disease: mechanisms, biological functions and therapeutic targets. [PDF]

Epigenetics Chromatin
Ji Y, Liu S, Zhang Y, Min Y, Wei L, Guan C, Yu H, Zhang Z.   +7 more
europepmc   +1 more source

Anti-histone and anti-nucleosome rather than anti-dsDNA antibodies associate with IFN-induced biomarkers in Sudanese and Swedish SLE patients. [PDF]

Rheumatology (Oxford)
Elbagir S, Mohammed NA, Oke V, Larsson A, Nilsson J, Elshafie A, Elagib EM, Nur MAM, Gunnarsson I, Svenungsson E, Rönnelid J.   +10 more
europepmc   +1 more source

The developmental basis of floral nectary diversity and evolution

New Phytologist, EarlyView.
Summary Nectar is a central bridge between angiosperms and animal mutualists. It is produced by specialized structures termed nectaries, which can be found on different plant organs. Consumption of floral nectar by pollinators and the subsequent transfer of pollen contribute to the reproductive success of both angiosperms and their pollinators.
Irene T. Liao, Yan Gong, Elena M. Kramer, Lachezar A. Nikolov   +3 more
wiley   +1 more source

Genome-wide transcriptional silencing and mRNA stabilization allow the coordinated expression of the meiotic program in mice. [PDF]

Nucleic Acids Res
Bellutti L, Chan Sock Peng E, Cluzet V, Guerquin MJ, Rolland A, Messiaen S, Llano E, Dereli I, Martini E, Tóth A, Pendás AM, Chalmel F, Livera G.   +12 more
europepmc   +1 more source