Results 221 to 230 of about 123,835 (338)

Epigenetic modification of hypothalamic neuropeptides and metabolic hormone receptors in metabolic health. [PDF]

Front Endocrinol (Lausanne)
Oladun B, Mall S, Kim MH.
europepmc   +1 more source

Season of birth and variations in male reproductive health: A population‐based cohort study

Andrology, EarlyView.
Abstract Background Season of birth has been associated with various later reproductive health outcomes in women, but little is known on the potential associations in men. Objectives To investigate the association between season of birth and semen characteristics, testes volume and reproductive hormone levels in young men.
Anne Gaml‐Sørensen, Nis Brix, Sandra Søgaard Tøttenborg, Karin Sørig Hougaard, Siri Eldevik Håberg, Mikko Myrskylä, Gunnar Toft, Jens Peter Ellekilde Bonde, Cecilia Høst Ramlau‐Hansen   +8 more
wiley   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

A ternary-code DNA methylome atlas of mouse tissues. [PDF]

Genome Biol
Lee SM, Goldberg DC, Cloud C, Parker JB, Krapp C, Loo CE, Kim E, Zhao I, Jin C, Porecha R, Bartolomei MS, Kohli RM, Zhou W.   +12 more
europepmc   +1 more source

Speedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization. [PDF]

EMBO J
Liu D, Zhang Y, Li D, Jiang B, Zhao X, Li Y, Lin Z, Zhao Y, Hu Z, Deng S, Li Z, Lu H, Chan KKL, Yeung WSB, Kaldis P, Yao C, Wang H, Chow LT, Liu K.   +18 more
europepmc   +1 more source

3D imaging of neuronal inclusions and protein aggregates in human neurodegeneration by multiscale x‐ray phase‐contrast tomography

Brain Pathology, EarlyView.
x‐ray phase‐contrast tomography enabled three‐dimensional, label‐free visualization and quantification of protein aggregates in neurodegenerative diseases with isotropic submicrometer resolution. The study revealed distinct electron density patterns in Lewy bodies, Hirano bodies, granulovacuolar degeneration, and amyloid plaques, highlighting their ...
Jonas Franz, Jakob Reichmann, Marina Eckermann, Thea Würfel, Artur Groh, Syed Fatima Qadri, Katja Schulz, Brit Mollenhauer, Christine Stadelmann, Tim Salditt   +9 more
wiley   +1 more source

Epigenetic Changes Associated With Obesity-related Metabolic Comorbidities. [PDF]

J Endocr Soc
Sandovici I, Morais T, Constância M, Monteiro MP.   +3 more
europepmc   +1 more source

DysRegNet: Patient‐specific and confounder‐aware dysregulated network inference towards precision therapeutics

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Gene regulation is frequently altered in diseases in unique and patient‐specific ways. Hence, personalised strategies have been proposed to infer patient‐specific gene‐regulatory networks. However, existing methods do not scale well because they often require recomputing the entire network per sample.
Johannes Kersting, Olga Lazareva, Zakaria Louadi, Jan Baumbach, David B. Blumenthal, Markus List   +5 more
wiley   +1 more source

Whole-genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia. [PDF]

HGG Adv
Li R, Gagliano Taliun SA, Liao K, Flickinger M, Sobell JL, Genovese G, Locke AE, Chiu RR, LeFaive J, Wang J, Martins T, Chapman S, Neumann A, Handsaker RE, Arnett DK, Barnes KC, Boerwinkle E, Braff D, Cade BE, Fornage M, Gibbs RA, Hoth KF, Hou L, Kooperberg C, Loos RJF, Metcalf GA, Montgomery CG, Morrison AC, Qin ZS, Redline S, Reiner AP, Rich SS, Rotter JI, Taylor KD, Viaud-Martinez KA, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium, Genomic Psychiatry Cohort Investigators, Bigdeli TB, Gabriel S, Zollner S, Smith AV, Abecasis G, McCarroll SA, Pato MT, Pato CN, Boehnke M, Knowles J, Kang HM, Ophoff RA, Ernst J, Scott LJ.   +52 more
europepmc   +1 more source

Reversibility of sex changes in the plant kingdom: more important than we thought?

Biological Reviews, EarlyView.
ABSTRACT Compared to animals, plants show a wide range of reproductive strategies with different degrees of sex separation (e.g. dioecy, monoecy, hermaphroditism). While sex expression was previously thought to be genetically determined and fixed in plants, accumulating evidence suggests that sex expression can change reversibly even within one ...
Iris Sammarco, Eliška Krtilová, Marek Slovák, Clément Lafon Placette   +3 more
wiley   +1 more source