Results 261 to 270 of about 128,998 (343)

Genome‐wide and gene‐specific DNA methylation across developmental stages in Pogonomyrmex californicus: A socially polymorphic ant

Insect Molecular Biology, EarlyView.
Comparison between developmental stages (larvae, pupae, worker) in Pogonomyrmex californicus revealed significant stage‐specific differences in Gene Body Methylated frequencies. Methylation sites were highly correlated between WGBS and ONT in P. californicus Genome‐wide methylation was low (~3%) and highly clustered within gene bodies (GBM), especially
Tania Chavarria‐Pizarro, Mohammed Errbii, Janina Rinke, Lukas Schrader, Jürgen Gadau   +4 more
wiley   +1 more source

The emerging role of epigenetic regulation in pain sensitization associated with headache disorders. [PDF]

J Headache Pain
Tao Y, Cai X, Sun Y, Lu W, Wang S, Huang Z, Zhang Y, Tao J, Zhang Y.   +8 more
europepmc   +1 more source

Differential peritoneal resident macrophage depletion and omental milky spot disruption after high versus low clodronate‐loaded liposome dose treatment

Immunology &Cell Biology, EarlyView.
In this study, we found that intraperitoneal injection of a high (standard) clodronate‐loaded liposome dose induced persistent peritoneal macrophage depletion, paralleled by marked inflammation and compromised omental integrity. Conversely, low liposome dose caused transient macrophage depletion, low inflammation and no omental alterations, ensuring ...
Margarita Ferriz, Natalia Álvarez‐Ladrón, Alejandra Gutiérrez‐González, Marta H. Fernández‐Sesma, Ana Starešinčić, Carlos Ardavín   +5 more
wiley   +1 more source

The Differentially Regulated Cousins: Insights into the Differences in Transcriptional Regulatory Mechanisms Between HTLV-1 and HIV-1. [PDF]

Viruses
Reda O, Satou Y.
europepmc   +1 more source

Interferon Regulatory Factor 2 (IRF2) Suppression Enhances Murine Cardiac Allograft Survival Through Immune Evasion

Immunology, EarlyView.
Our data show that suppressing IRF2, genetically or by siRNA, modulates PD‐L1 and MHC‐I levels. This induced immune‐evasive state critically underlies the significantly prolonged survival of cardiac allografts, revealing a novel therapeutic avenue.
Li Tian, Man Zhang, Yuliang Guo, Sheng Chang, Zhonghua Klaus Chen, Hongmin Zhou   +5 more
wiley   +1 more source

3-D biomechanics and epigenomics reveal atypical fibroblast responses in cardiometabolic disease. [PDF]

Am J Physiol Heart Circ Physiol
Ibrahim SY, Holdiness R, Thadisena A, Boyle KE, Jun SR, Bagchi RA.   +5 more
europepmc   +1 more source

Genetic Determinants of Peanut‐Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP Study

Immunology, EarlyView.
A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanika Kanchan, Karen Cerosaletti, James A. Perry, George DuToit, Monali Manohar, Hua Ling, Justin E. Paschall, Srinath Sanda, R. Sharon Chinthrajah, Gerald T. Nepom, Kari C. Nadeau, Stacie M. Jones, Gideon Lack, Ingo Ruczinski, Rasika A. Mathias   +14 more
wiley   +1 more source

Practitioner Review: Infant mental health meets cell and molecular biology – a look to the future

Journal of Child Psychology and Psychiatry, EarlyView.
Background A major research effort in the past two decades has begun to illuminate how experience ‘gets under the skin’ – that is – the cellular and molecular processes that are associated with adversity and resilience. Methods We selectively review three areas of this research: epigenetics, especially DNA methylation, telomere length, and inflammatory
Charles H. Zeanah, Megan Hare, Katherine Cowhey, Stacy S. Drury   +3 more
wiley   +1 more source

Chromosome and sex-chromatin studies of patients with hypospadias

The Turkish Journal of Pediatrics, 1969
E Tunçbilek
doaj  

New insights into the putative XX/XY sex chromosomal system in blue‐eyed red‐fin pleco Hypostomus soniae (Siluriformes, Loricariidae)

Journal of Fish Biology, EarlyView.
Abstract Blue‐eyed red‐fin pleco Hypostomus soniae (family Loricariidae) presented a putative sex system XX/XY in early stage. Aiming to explore the inter‐populational karyotypic variation and proposed emergence of the XX/XY system, we studied 13 H. soniae individuals (6 males, 7 females) from the Tapajós River.
Luan Aércio Melo Maciel, Renata Coelho Rodrigues Noronha, Bruno Rafael Ribeiro de Almeida, Manoella Gemaque Cavalcante, Cleusa Yoshiko Nagamachi, Julio Cesar Pieczarka, Luís Reginaldo R. Rodrigues   +6 more
wiley   +1 more source