Enhanced chromatin accessibility of the dosage compensated Drosophila male X-chromosome requires the CLAMP zinc finger protein. [PDF]
PLoS ONE, 2017 The essential process of dosage compensation is required to equalize gene expression of X-chromosome genes between males (XY) and females (XX). In Drosophila, the conserved Male-specific lethal (MSL) histone acetyltransferase complex mediates dosage ...
Jennifer Urban +8 more
doaj +1 more source
RANK signaling in osteoclast precursors results in a more permissive epigenetic landscape and sexually divergent patterns of gene expression [PDF]
PeerJ, 2023 Background Sex is an important risk factor in the development of osteoporosis and other bone loss disorders, with women often demonstrating greater susceptibility than men. While variation in sex steroids, such as estradiol, accounts for much of the risk,
Abigail L. Keever +4 more
doaj +2 more sources
Deciphering the Role of the Barr Body in Malignancy: An insight into head and neck cancer
Sultan Qaboos University Medical Journal, 2018 X chromosome inactivation is the epitome of epigenetic regulation and long non-coding ribonucleic acid function. The differentiation status of cells has been ascribed to X chromosome activity, with two active X chromosomes generally only observed in ...
Deepti Sharma +4 more
doaj +1 more source
The Effect of Sex Chromatin on Some Reproductive Traits of local Sheep in Erbil
مجلة مركز بحوث التقنيات الاحيائية, 2015 This study was conducted on local sheep belongs to private flock in Erbil plain during the period 4 /11/2011 till 25/10/2012. The investigation included 65 local sheep to study the effect of sex chromatin frequency on the Daily Milk Yield (DMY), weight ...
Nihad Ahmad Ameen Ameen +1 more
doaj +1 more source
Molecular Neurodegeneration, 2021 Background In the post-GWAS era, there is an unmet need to decode the underpinning genetic etiologies of late-onset Alzheimer’s disease (LOAD) and translate the associations to causation.
Julio Barrera +15 more
doaj +1 more source
Sex chromatin of hydatidiform moles. [PDF]
Journal of Medical Genetics, 1969 Y.W. Loke
openalex +5 more sources
Role of Sex Chromatin on performance in the Arabi sheep
The Iraqi Journal of Veterinary Medicine, 2017 This study was conducted on 122 Arabi sheep belonged to private flock in Erbil plain Kurdistan region- Iraq, from July/ 2014 to August/ 2015 for studying the role of sex chromatin on daily milk production, total milk production, lactation period ...
Salim Omar Raoof
doaj +1 more source
The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation. [PDF]
PLoS Biology, 2013 Sex chromosomes originated from autosomes but have evolved a highly specialized chromatin structure. Drosophila Y chromosomes are composed entirely of silent heterochromatin, while male X chromosomes have highly accessible chromatin and are ...
Qi Zhou +5 more
doaj +1 more source
Chromatin accessibility, not 5mC methylation covaries with partial dosage compensation in crows.
PLoS Genetics, 2023 The evolution of genetic sex determination is often accompanied by degradation of the sex-limited chromosome. Male heterogametic systems have evolved convergent, epigenetic mechanisms restoring the resulting imbalance in gene dosage between diploid ...
Ana Catalán +3 more
doaj +1 more source