Results 21 to 30 of about 60,046 (266)
Background In the post-GWAS era, there is an unmet need to decode the underpinning genetic etiologies of late-onset Alzheimer’s disease (LOAD) and translate the associations to causation.
Julio Barrera+15 more
doaj +1 more source
Role of Sex Chromatin on Performance in the Crossbred Cows
This study was conducted on a total of 67crossbred cows in Erbil plain during the period from July/ 2014 to April / 2015, to study the role of sex chromatin shapes (Drum stick, Sessile nodule, Tear drop and Small club) on Daily Milk Yield (DMY ...
Salim Omar Raoof+2 more
doaj +1 more source
Heterogeneous interactions and polymer entropy decide organization and dynamics of chromatin domains [PDF]
Chromatin is known to be organized into multiple domains of varying sizes and compaction. While these domains are often imagined as static structures, they are highly dynamic and show cell-to-cell variability. Since processes such as gene regulation and DNA replication occur in the context of these domains, it is important to understand their ...
arxiv +1 more source
How germline genes promote malignancy in cancer cells
We hypothesize that activation of a “germline program” promotes oncogenesis. Expression of otherwise germline specific genes may result in pseudomeiotic activity, thereby promoting oncogenesis through genomic instability. Other processes that are differentially regulated in the germline, such as migration and epigenetic – and metabolic plasticity, may ...
Jan Willem Bruggeman+4 more
wiley +1 more source
Deciphering the Role of the Barr Body in Malignancy: An insight into head and neck cancer
X chromosome inactivation is the epitome of epigenetic regulation and long non-coding ribonucleic acid function. The differentiation status of cells has been ascribed to X chromosome activity, with two active X chromosomes generally only observed in ...
Deepti Sharma+4 more
doaj +1 more source
Role of sex chromatin on performance in the local (black) goats
This study was conducted on local black goats belongs to private flock in Erbil plain from period July/ 2014 to April/ 2015. The study included 116 local black goats to study role of sex chromatin on the daily milk production (DMP), total milk ...
Salim Omar Raoof+3 more
doaj +1 more source
Several thousand sex-differential distal enhancers have been identified in mouse liver; however, their links to sex-biased genes and the impact of any sex-differences in nuclear organization and chromatin interactions are unknown. To address these issues,
Bryan J. Matthews, David J. Waxman
doaj +1 more source
Abstract The association of overweight/obesity, and central obesity with thiocyanate (SCN), perchlorate (CIO), and nitrate (NO) in childhood and adolescence is unclear. Therefore, this study aimed to explore this association in 4447 participants comprising children and adolescents (aged 6–19 years) using data from the United States National Health and ...
Qi Jiang, Qin Li
wiley +1 more source
Role of Sex Chromatin on performance in the Arabi sheep
This study was conducted on 122 Arabi sheep belonged to private flock in Erbil plain Kurdistan region- Iraq, from July/ 2014 to August/ 2015 for studying the role of sex chromatin on daily milk production, total milk production, lactation period ...
Salim Omar Raoof
doaj +1 more source
Activity-driven phase transition causes coherent flows of chromatin [PDF]
We discover a new type of nonequilibrium phase transition in a model of chromatin dynamics, which accounts for the coherent motions that have been observed in experiment. The coherent motion is due to the long-range cooperation of molecular motors tethered to chromatin.
arxiv +1 more source