A mammal-specific Doublesex homolog associates with male sex chromatin and is required for male meiosis. [PDF]
PLoS Genetics, 2007 Gametogenesis is a sexually dimorphic process requiring profound differences in germ cell differentiation between the sexes. In mammals, the presence of heteromorphic sex chromosomes in males creates additional sex-specific challenges, including ...
Shinseog Kim +6 more
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Biology of Sex Differences, 2022 Background Birds exhibit a unique asymmetry in terms of gonad development. The female left gonad generates a functional ovary, whereas the right gonad regresses. In males, both left and right gonads would develop into testes.
Yunqi Jiang +7 more
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RANK signaling in osteoclast precursors results in a more permissive epigenetic landscape and sexually divergent patterns of gene expression [PDF]
PeerJ, 2023 Background Sex is an important risk factor in the development of osteoporosis and other bone loss disorders, with women often demonstrating greater susceptibility than men. While variation in sex steroids, such as estradiol, accounts for much of the risk,
Abigail L. Keever +4 more
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A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse. [PDF]
, 2012 Intragenomic conflicts arise when a genetic element favours its own transmission to the detriment of others. Conflicts over sex chromosome transmission are expected to have influenced genome structure, gene regulation, and speciation.
Affara, Nabeel A. +5 more
core +7 more sources
Ancestral Chromatin Configuration Constrains Chromatin Evolution on Differentiating Sex Chromosomes in Drosophila. [PDF]
PLoS Genetics, 2015 Sex chromosomes evolve distinctive types of chromatin from a pair of ancestral autosomes that are usually euchromatic. In Drosophila, the dosage-compensated X becomes enriched for hyperactive chromatin in males (mediated by H4K16ac), while the Y ...
Qi Zhou, Doris Bachtrog
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Enhanced chromatin accessibility of the dosage compensated Drosophila male X-chromosome requires the CLAMP zinc finger protein. [PDF]
PLoS ONE, 2017 The essential process of dosage compensation is required to equalize gene expression of X-chromosome genes between males (XY) and females (XX). In Drosophila, the conserved Male-specific lethal (MSL) histone acetyltransferase complex mediates dosage ...
Jennifer Urban +8 more
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Differences of size and shape of active and inactive X-chromosome domains in human amniotic fluid cell nuclei [PDF]
, 1993 It is a widely held belief that the inactive X-chromosome (Xi) in female cell nuclei is strongly condensed as compared to the largely decondensed active X-chromosome (Xa).
Barr +39 more
core +1 more source
UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells [PDF]
, 2012 The N-end rule pathway is a proteolytic system in which its recognition components (N-recognins) recognize destabilizing N-terminal residues of short-lived proteins as an essential element of specific degrons, called N-degrons.
An, JY +12 more
core +1 more source
Deciphering the Role of the Barr Body in Malignancy: An insight into head and neck cancer
Sultan Qaboos University Medical Journal, 2018 X chromosome inactivation is the epitome of epigenetic regulation and long non-coding ribonucleic acid function. The differentiation status of cells has been ascribed to X chromosome activity, with two active X chromosomes generally only observed in ...
Deepti Sharma +4 more
doaj +1 more source
The Effect of Sex Chromatin on Some Reproductive Traits of local Sheep in Erbil
مجلة مركز بحوث التقنيات الاحيائية, 2015 This study was conducted on local sheep belongs to private flock in Erbil plain during the period 4 /11/2011 till 25/10/2012. The investigation included 65 local sheep to study the effect of sex chromatin frequency on the Daily Milk Yield (DMY), weight ...
Nihad Ahmad Ameen Ameen +1 more
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