Results 81 to 90 of about 60,046 (266)

Landscape transcriptomics as a tool for addressing global change effects across diverse species

Molecular Ecology Resources, EarlyView., 2023
Abstract Landscape transcriptomics is an emerging field studying how genome‐wide expression patterns reflect dynamic landscape‐scale environmental drivers, including habitat, weather, climate, and contaminants, and the subsequent effects on organismal function. This field is benefitting from advancing and increasingly accessible molecular technologies,
Jason Keagy, Chloe P. Drummond, Kadeem J. Gilbert, Christina M. Grozinger, Jill Hamilton, Heather M. Hines, Jesse Lasky, Cheryl A. Logan, Ruairidh Sawers, Tyler Wagner   +9 more
wiley   +1 more source

Sex Chromatin Demonstration by A Modified Hair Root Sheath Technique

Indian Journal of Plastic Surgery, 1972
A modified technique for demonstration of sex chromatin in nuclei of hair root sheath has been described and its advantages are discussed.
Ramesh Arora, R. N. Sharma
doaj   +1 more source

A Case of Prader‐Willi Syndrome With a Deletion Including MAGEL2, NDN, and MKRN3, but Excluding SNRPN and SNORD116

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Prader‐Willi syndrome (PWS) is a neurodevelopmental disorder typically caused by large deletions or imprinting defects on chromosome 15q11.2, encompassing multiple genes. While the contribution of individual genes to the PWS phenotype remains unclear, previous studies suggested that isolated deletions of MAGEL2, NDN, and MKRN3, excluding the ...
Jannis Buecking, Yu An, Weimin Bi, Katrin Hinderhofer, Susanne Theiß, Anne Slavotinek, Christian P. Schaaf   +6 more
wiley   +1 more source

Assembly of female and male hihi genomes (stitchbird; Notiomystis cincta) enables characterization of the W chromosome and resources for conservation genomics

Molecular Ecology Resources, EarlyView., 2023
Abstract A high‐quality reference genome can be a valuable resource for threatened species by providing a foundation to assess their evolutionary potential to adapt to future pressures such as environmental change. We assembled the genome of a female hihi (Notiomysits cincta), a threatened passerine bird endemic to Aotearoa New Zealand.
Sarah Bailey, Joseph Guhlin, Dinindu S. Senanayake, Phoebe Scherer, Patricia Brekke, John G. Ewen, Anna W. Santure, Annabel Whibley   +7 more
wiley   +1 more source

Compound Heterozygous Variants in ZSWIM7 Gene Linked to Infertility and Its Role in Gonadal Development

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study aims to elucidate the role of the ZSWIM7 gene in the etiology of infertility, focusing on its potential association with premature ovarian insufficiency and azoospermia. We investigated an 18‐year‐old female patient who presented with primary amenorrhea, hypoplasia of the uterus and ovaries, Tanner stage II breast and pubic hair ...
Denise M. Christofolini, Guilherme Pinn, Thainá Vilella, Maria I. Melaragno, Mariana Moysés‐Oliveira, Luciano Pompei, Rare Genomes Project Consortium, Bianca Bianco, Caio P. Barbosa   +8 more
wiley   +1 more source

Sex at the interface: the origin and impact of sex differences in the developing human placenta

Biology of Sex Differences, 2022
Highlights Placental sex differences exist from early prenatal development, and may help explain sex differences in pregnancy outcomes. Transcriptome profiling of early to mid-gestation placenta reveals that immune signaling is a hub of early prenatal ...
Amy E. Braun, Olivia R. Mitchel, Tania L. Gonzalez, Tianyanxin Sun, Amy E. Flowers, Margareta D. Pisarska, Virginia D. Winn   +6 more
doaj   +1 more source

DNA damage contributes to age‐associated differences in SARS‐CoV‐2 infection

Aging Cell, Volume 21, Issue 12, December 2022., 2022
Our data suggest DNA damage contributes to age‐associated differences in SARS‐CoV‐2 infection and provide a novel target for anti‐viral intervention. Abstract Coronavirus disease 2019 (COVID‐19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is known to disproportionately affect older individuals.
Rui Jin, Chang Niu, Fengyun Wu, Sixin Zhou, Tao Han, Zhe Zhang, Entao Li, Xiaona Zhang, Shanrong Xu, Jiadong Wang, Shen Tian, Wei Chen, Qinong Ye, Cheng Cao, Long Cheng   +14 more
wiley   +1 more source

X Inactivation and Escape: Epigenetic and Structural Features

Frontiers in Cell and Developmental Biology, 2019
X inactivation represents a complex multi-layer epigenetic mechanism that profoundly modifies chromatin composition and structure of one X chromosome in females.
He Fang, Christine M. Disteche, Christine M. Disteche, Joel B. Berletch   +3 more
doaj   +1 more source

Progress in research on osteoporosis secondary to SARS‐CoV‐2 infection

Animal Models and Experimental Medicine, EarlyView.
This review explores the potential mechanisms, complications, risk factors, and future research directions related to osteoporosis secondary to SARS‐CoV‐2 infection. Key mechanisms include an imbalance between osteoclast and osteoblast activity driven by direct viral effects on bone, inflammation, hypoxia, dysregulation of noncoding RNAs, and metabolic
Jinlong Wang, Yibai Xiong, Zhiqi Song, Yanhong Li, Ling Zhang, Chuan Qin   +5 more
wiley   +1 more source

SEX CHROMATIN IN THE AMNION OF THE PIG [PDF]

Reproduction, 1971
In the domestic pig, Sus scrofa, sexual dimorphism, as indicated by the presence of the sex chromatin body, is detectable in neurones of the brain and spinal cord (Cantwell, Johnston & Zeller, 1958; Hay & Moore, 1961; Harvey, 1969). Attempts to detect this feature in non-nervous tissue have, with one exception, failed. Hoshino & Toryu (1958) claimed to
openaire   +3 more sources