Results 11 to 20 of about 2,151,922 (308)

Numerous transitions of sex chromosomes in Diptera.

PLoS Biology, 2015
Many species groups, including mammals and many insects, determine sex using heteromorphic sex chromosomes. Diptera flies, which include the model Drosophila melanogaster, generally have XY sex chromosomes and a conserved karyotype consisting of six ...
Beatriz Vicoso, Doris Bachtrog
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Unique sex chromosome translocations and evolutionary strata in two Sylvioidea songbird families [PDF]

BMC Genomics
Avian genomes are typically stable, yet instances of chromosome fissions, fusions and translocations are known across various lineages. For example, multiple sex chromosome translocations have been described in the superfamily Sylvioidea.
Thomas J. Brown, Simon J. Ellerstrand, Hanna Sigeman, Martim Melo, Max Lundberg, Bengt Hansson   +5 more
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The key role of repeated DNAs in sex chromosome evolution in two fish species with ZW sex chromosome system [PDF]

Molecular Cytogenetics, 2012
Despite substantial progress, there are still several gaps in our knowledge about the process of sex chromosome differentiation. The degeneration of sex-specific chromosome in some species is well documented, but it is not clear if all species follow the
de Bello Cioffi Marcelo, Kejnovský Eduard, Marquioni Vinicius, Poltronieri Juliana, Molina Wagner, Diniz Débora, Bertollo Luiz Antonio   +6 more
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Y chromosome functions in mammalian spermatogenesis

eLife, 2021
The mammalian Y chromosome is critical for male sex determination and spermatogenesis. However, linking each Y gene to specific aspects of male reproduction has been challenging.
Jeremie Subrini, James Turner
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CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes

Nature Communications, 2021
In areas such as animal research and agriculture a single sex is often required in abundance, leading to wasted resources and ethical considerations. Here the authors develop a CRISPR/Cas9 mediated synthetic lethal system that enables the production of ...
Charlotte Douglas, Valdone Maciulyte, Jasmin Zohren, Daniel M. Snell, Shantha K. Mahadevaiah, Obah A. Ojarikre, Peter J. I. Ellis, James M. A. Turner   +7 more
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Snake W Sex Chromosome: The Shadow of Ancestral Amniote Super-Sex Chromosome

Cells, 2020
Heteromorphic sex chromosomes, particularly the ZZ/ZW sex chromosome system of birds and some reptiles, undergo evolutionary dynamics distinct from those of autosomes. The W sex chromosome is a unique karyological member of this heteromorphic pair, which
Worapong Singchat, Syed Farhan Ahmad, Nararat Laopichienpong, Aorarat Suntronpong, Thitipong Panthum, Darren K. Griffin, Kornsorn Srikulnath   +6 more
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The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes

Nature Communications, 2020
If left unrepaired, meiotic DSBs are toxic to mammalian cells, thus oocytes in which DSBs persist are eliminated by the DNA-damage checkpoint. Here the authors provide insights into the roles of PUMA, NOXA and BAX during DNA damage checkpoint that ...
Elias ElInati, Agata P. Zielinska, Afshan McCarthy, Nada Kubikova, Valdone Maciulyte, Shantha Mahadevaiah, Mahesh N. Sangrithi, Obah Ojarikre, Dagan Wells, Kathy K. Niakan, Melina Schuh, James M. A. Turner   +11 more
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Partial Amniote Sex Chromosomal Linkage Homologies Shared on Snake W Sex Chromosomes Support the Ancestral Super-Sex Chromosome Evolution in Amniotes

Frontiers in Genetics, 2020
Squamate reptile chromosome 2 (SR2) is thought to be an important remnant of an ancestral amniote super-sex chromosome, but a recent study showed that the Siamese cobra W sex chromosome is also a part of this larger ancestral chromosome.
Worapong Singchat, Worapong Singchat, Syed Farhan Ahmad, Syed Farhan Ahmad, Siwapech Sillapaprayoon, Siwapech Sillapaprayoon, Narongrit Muangmai, Prateep Duengkae, Surin Peyachoknagul, Rebecca E. O’Connor, Darren K. Griffin, Kornsorn Srikulnath, Kornsorn Srikulnath, Kornsorn Srikulnath, Kornsorn Srikulnath, Kornsorn Srikulnath, Kornsorn Srikulnath   +16 more
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Genome-wide association mapping uncovers sex-associated copy number variation markers and female hemizygous regions on the W chromosome in Salix viminalis

BMC Genomics, 2021
Background Sex chromosomes are in some species largely undifferentiated (homomorphic) with restricted sex determination regions. Homomorphic but different sex chromosomes are found in the closely related genera Populus and Salix indicating flexible sex ...
Henrik R. Hallingbäck, Pascal Pucholt, Pär K. Ingvarsson, Ann Christin Rönnberg-Wästljung, Sofia Berlin   +4 more
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Genomic assessment of local adaptation in dwarf birch to inform assisted gene flow

Evolutionary Applications, 2020
When populations of a rare species are small, isolated and declining under climate change, some populations may become locally maladapted. Detecting this maladaptation may allow effective rapid conservation interventions, even if based on incomplete ...
James S. Borrell, Jasmin Zohren, Richard A. Nichols, Richard J. A. Buggs   +3 more
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