Results 21 to 30 of about 2,151,922 (308)

IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche

Nature Communications, 2020
The signals regulating the establishment and maintenance of the pluripotent epiblast in human embryos are unclear. Here, the authors use a bioinformatics approach to identify the role of IGF1 in human embryo development, and from this, propose a culture ...
Sissy E. Wamaitha, Katarzyna J. Grybel, Gregorio Alanis-Lobato, Claudia Gerri, Sugako Ogushi, Afshan McCarthy, Shantha K. Mahadevaiah, Lyn Healy, Rebecca A. Lea, Miriam Molina-Arcas, Liani G. Devito, Kay Elder, Phil Snell, Leila Christie, Julian Downward, James M. A. Turner, Kathy K. Niakan   +16 more
doaj   +1 more source

Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia [PDF]

, 2013
© 2013 Mac Keith Press.Sex chromosome aneuploidies increase the risk of spoken or written language disorders but individuals with specific language impairment (SLI) or dyslexia do not routinely undergo cytogenetic analysis. We assess the frequency of sex
Newbury, Dianne F, Bolton, Patrick F, Paracchini, S., Simpson, N., Simkin, Z., Talcott, J., Scerri, TS, O'Hare, A., Newbury, D., Addis, Laura, Knight, Julian, Fairfax, Benjamin P, Clark, A., Bishop, D. V M, Talcott, JB, Addis, L., Stein, J., Knight, J., Knight, Julian C, Slonims, V., Fairfax, Benjamin P., Slonims, Vicky, O'Hare, Anne, O'Hare, A, Addis, L, ?, ?, Pickles, A., Brandler, WM, Everitt, A., Hennessy, ER, Stein, John, Watson, J, Clark, Ann, Fairfax, BP, Cohen, W., Cowie, H., Conti-Ramsden, G., Paracchini, Silvia, Watson, J., Simpson, Nuala H, Stein, John F., Hennessy, Elizabeth R., Nudel, R., Seckl, J., Bolton, PF, Scerri, Thomas S, Baird, Gillian, Hennessy, E., Simpson, Nuala H., Talcott, Joel B., Talcott, Joel B, Baird, G., SLI Consortium, Brandler, W., Fisher, Simon E, Consortium, Sli, Brandler, William M., Baird, G, Fairfax, B., Knight, Julian C., Fisher, S., Nasir, J., Fisher, SE, Simpson, NH, Conti-Ramsden, G, Conti-Ramsden, Gina, Monaco, A. P., Hennessy, Elizabeth R, Paracchini, S, Scerri, T., Slonims, V, Clark, A, Watson, Jocelynne, Newbury, Dianne F., Brandler, William M, Simonoff, E., Newbury, DF, Fisher, Simon E., Scerri, Thomas S., Bolton, Patrick F., Paracchini, Silvia; id_orcid   +80 more
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Independent stratum formation on the avian sex chromosomes reveals inter-chromosomal gene conversion and predominance of purifying selection on the w chromosome [PDF]

, 2014
We used a comparative approach spanning three species and 90 million years to study the evolutionary history of the avian sex chromosomes. Using whole transcriptomes, we assembled the largest cross-species dataset of W-linked coding content to date.
Wright, Alison E, Harrison, Peter W, Mank, JE, Wright, AE, Montgomery, SH, Mank, Judith E, Pointer, Marie A, Harrison, PW, Pointer, MA, Montgomery, Stephen H   +9 more
core   +1 more source

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits [PDF]

, 2002
We tested the hypothesis that genes encoded on the sex chromosomes play a direct role in sexual differentiation of brain and behavior. We used mice in which the testis-determining gene (Sry) was moved from the Y chromosome to an autosome (by deletion of ...
Robin Lovell-Badge, De Vries, Geert, Auger, CJ, Lovell-Badge, R, Catherine J. Auger, Elka M. Scordalakes, Swain, A, Simerly, Richard B., Lovell-Badge, Robin, Richard B. Simerly, Amanda Swain, Arnold, Arthur P., Simerly, RB, Burgoyne, PS, Scordalakes, Elka M., Emilie F. Rissman, Geert J. De Vries, Liang-Yo Yang, Burgoyne, Paul S., Yang, Liang-Yo, Yang, L-Y, Rissman, EF, Rissman, Emilie F., Paul S. Burgoyne, De Vries, G, Arnold, AP, Arthur P. Arnold, Scordalakes, EM, Swain, Amanda, Auger, Catherine J.   +29 more
core   +1 more source

Early events in the evolution of the Silene latifolia Y chromosome: Male specialization and recombination arrest [PDF]

, 2007
Understanding the origin and evolution of sex chromosomes requires studying recently evolved X-Y chromosome systems such as those in some flowering plants.
Georgiev, Sevdalin, Zluvova, Jitka, Janousek, Bohuslav, Georgiev, S., Vyskot, Boris, Negrutiu, Loan, Negrutiu, Ioan, Charlesworth, D., Charlesworth, Deborah   +8 more
core   +1 more source

SEX CHROMOSOMES IN AMNIOTA [PDF]

Evolution, 1957
During the past 25 years the chromnosomal conditions in Vertebrates have been the subject of a great many investigations. With some justification it has been hoped that such work might add to our present knowledge of the evolutionary relation between the different classes of Vertebrates and, in this connection, special attention has been given to the ...
R. Matthey, J. M. van Brink
openaire   +1 more source

Evolutionary strata on the X chromosomes of the dioecious plant Silene latifolia: Evidence from new sex-linked genes [PDF]

, 2007
Despite its recent evolutionary origin, the sex chromosome system of the plant Silene latifolia shows signs of progressive suppression of recombination having created evolutionary strata of different X-Y divergence on sex chromosomes. However, even after
Bergero, Roberta, Forrest, Alan, Kamau, Esther, Charlesworth, Deborah   +3 more
core   +1 more source

Chromosome assignment of two cloned DNA probes hybridizing predominantly to human sex chromosomes [PDF]

, 1984
In situ hybridization experiments were carried out with two clones, YACG 35 and 2.8, which had been selected from two genomic libraries strongly enriched for the human Y chromosome.
Back, W., Cremer, Thomas, Rappold, Gudrun A., Cremer, Christoph, Bogenberger, J., Cooke, H. J.   +5 more
core   +1 more source

Turnover of multiple sex chromosomes in Harttia catfish (Siluriformes, Loricariidae): a glimpse from whole chromosome painting

Frontiers in Genetics, 2023
The remarkable fish biodiversity encompasses also great sex chromosome variability. Harttia catfish belong to Neotropical models for karyotype and sex chromosome research.
Francisco de Menezes Cavalcante Sassi, Geize Aparecida Deon, Alexandr Sember, Thomas Liehr, Osvaldo Takeshi Oyakawa, Orlando Moreira Filho, Luiz Antonio Carlos Bertollo, Marcelo Ricardo Vicari, Marcelo de Bello Cioffi   +8 more
doaj   +1 more source

Sex Chromosome Drive [PDF]

Cold Spring Harbor Perspectives in Biology, 2014
Sex chromosome drivers are selfish elements that subvert Mendel's first law of segregation and therefore are overrepresented among the products of meiosis. The sex-biased progeny produced then fuels an extended genetic conflict between the driver and the rest of the genome.
Helleu, Quentin, Gérard, Pierre, Montchamp-Moreau, Catherine   +2 more
openaire   +3 more sources