Combining chromosomal arm status and significantly aberrant genomic locations reveals new cancer subtypes [PDF]
, 2008 Many types of tumors exhibit chromosomal losses or gains, as well as local amplifications and deletions. Within any given tumor type, sample specific amplifications and deletionsare also observed.
Domany, Eytan +4 more
core +4 more sources
Implementation of non-invasive prenatal testing by semiconductor sequencing in a genetic laboratory [PDF]
, 2016 Objectives: To implement non-invasive prenatal testing (NIPT) for fetal aneuploidies with semiconductor sequencing in an academic cytogenomic laboratory and to evaluate the first 15-month experience on clinical samples.
De Smet, Matthias +7 more
core +2 more sources
Insect Sex Determination Manipulated by Their Endosymbionts: Incidences, Mechanisms and Implications
Insects, 2012 The sex-determining systems of arthropods are surprisingly diverse. Some species have male or female heterogametic sex chromosomes while other species do not have sex chromosomes.
Masaya Watanabe +2 more
doaj +1 more source
Prenatal Diagnosis and Pregnancy Outcome Analysis of High-risk Fetuses Suggested by Noninvasive Prenatal Screening [PDF]
Zhongguo quanke yixue, 2022 Background Noninvasive prenatal screening is more effective in screening for fetal aneuploidy than does traditional serological screening. We attempted to analyze the real-world data about the positive predictive value (PPV) for chromosome aneuploidy ...
Yan LUO, Bingyi ZHAO, Yanmei SUN, Haishen TIAN, Yali LI, Yanshang ZHANG, Jian GAO, Zhiqiang CUI
doaj +1 more source
Cytogenetic Findings in Mentally Retarded Iranian Patients
Balkan Journal of Medical Genetics, 2012 We conducted a cytogenetic study on 865 individuals with idiopathic mental retardation (MR) who were admitted to the Cytogenetics Department of the Iran Blood Transfusion Organisation (IBTO) Research Centre, Tehran, Iran; these were performed on blood ...
Nasiri F. +5 more
doaj +1 more source
Molecular cytotaxonomy of primates by chromosomal in situ suppression hybridization [PDF]
, 1990 A new strategy for analyzing chromosomal evolution in primates is presented using chromosomal in situ suppression (CISS) hybridization. Biotin-labeled DNA libraries from flow-sorted human chromosomes are hybridized to chromosome preparations of ...
Anna Jauch +22 more
core +1 more source
Archives of Pharmacy Practice, 2014 Objective: This study investigated the influence of sex and ageing on chromosomal damage and the role of life-style habits on the frequency of chromosomal aberrations (CAs) in peripheral blood lymphocytes (PBLs) of healthy Bosnian subjects. Materials and
Hilada Nefic, Jasmin Musanovic
doaj +1 more source
Seven-fluorochrome mouse M-FISH for high-resolution analysis of interchromosomal rearrangements [PDF]
, 2003 The mouse has evolved to be the primary mammalian genetic model organism. Important applications include the modeling of human cancer and cloning experiments. In both settings, a detailed analysis of the mouse genome is essential.
Geigl, J. +3 more
core +1 more source
Scandinavian Journal of Work, Environment & Health, 2013 OBJECTIVES: Structural chromosomal aberrations in blood lymphocytes represent a biomarker for cellular damage caused by genotoxic carcinogens and are an indicator of increased cancer risk.
Ludovit Musak +9 more
doaj +1 more source
Classical and molecular cytogenetic studies in some cattle breeds
Italian Journal of Animal Science, 2010 Numerical autosome aberrations have a few importance in the animal breeding since the carriers show generally abnormal body conformation. For this reason, these abnormalities are systematically eliminated from the animal population by the breeders during
G. Succi +7 more
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