Results 61 to 70 of about 15,433 (199)

Reproductive adverse events in patients with non‐Hodgkin lymphoma treated with chemotherapeutic regimens including cyclophosphamide, doxorubicin, vincristine, prednisone or CHOP with rituximab: A systematic review and meta‐analysis

open access: yesPediatric Discovery, EarlyView.
The regimen of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or CHOP with rituximab (R‐CHOP) is the first‐line treatment for non‐Hodgkin lymphoma (NHL). Nine articles involving 331 patients were included in the meta‐analysis, the pooled proportion of reproductive adverse events was 22.3% (95% CI 11.4%–33.2%; p < 0.001). The findings
Rong Han   +6 more
wiley   +1 more source

Urinary Proteomics and Systems Biology Link Eight Proteins to the Higher Risk of Hypertension and Related Complications in Blacks Versus Whites

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Blacks are more prone to salt‐sensitive hypertension than Whites. This cross‐sectional analysis of a multi‐ethnic cohort aimed to search for proteins potentially involved in the susceptibility to salt sensitivity, hypertension, and hypertension‐related complications.
De‐Wei An   +22 more
wiley   +1 more source

Bifenthrin resistance in Dalbulus maidis (Hemiptera: Cicadellidae): inheritance, cross‐resistance, and stability

open access: yesPest Management Science, EarlyView.
Resistance of Dalbulus maidis to bifenthrin was autosomal, incompletely dominant, and polygenic. Additionally, this resistance was unstable in the absence of selection pressure. Abstract BACKGROUND Pyrethroid insecticides have been a primary strategy for managing Dalbulus maidis (Hemiptera: Cicadellidae) in Brazil. Howeve, failures in the control of D.
Gabriel Silva Dias   +4 more
wiley   +1 more source

Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi   +6 more
wiley   +1 more source

Liposome‐Polymer Nanoparticles Loaded with Copper Diethyldithiocarbamate and 6‐Bromo‐Indirubin‐3′‐Oxime Enable the Treatment of Refractive Melanoma

open access: yesSmall, EarlyView.
Cancer cells are exposed to heightened levels of endoplasmic reticulum stress and inflammation within the tumor microenvironment which can lead to therapeutic resistance. To address this issue, liposome‐polymer nanoparticles loaded with copper diethyldithiocarbamate (CuET), a potent inhibitor of the p97‐UFD1‐NPL4 protein complex, and the anti ...
Radu A. Paun   +4 more
wiley   +1 more source

Emerging trends in the management of non‐obstructive azoospermia

open access: yesUroPrecision, EarlyView.
Abstract Ten percent of infertile males have azoospermia, classified into obstructive and nonobstructive types, which require specific medical or surgical treatments. In nonobstructive azoospermia, advancements in microsurgery allow for effective sperm retrieval in about half of cases.
Mina Saad   +4 more
wiley   +1 more source

Range‐wide study in a sexually polymorphic wild strawberry reveals climatic and soil associations of sex ratio, sexual dimorphism and sex chromosomes

open access: yesJournal of Ecology, EarlyView.
A landscape‐level perspective revealed that variation in soil and climate factors can explain geospatial variation in sex ratio and sexual dimorphism in a wild strawberry. Variation in sex ratio was associated more with soil resources than climate, while variation in sexual dimorphism was the result of sex‐differential responses to climate for ...
Nevin Cullen   +6 more
wiley   +1 more source

Sex ratio and spatial distribution of Cycas panzhihuaensis in Sichuan Panzhihua cycad National Nature Reserve

open access: yesPlant Species Biology, EarlyView.
The sex ratio of the endemic gymnosperm Cycas panzhihuaensis is determined by the potential sex‐determining gene MADS‐Y. The study examined the sex dimorphism and spatial distribution of male and female individuals. The genotypic sex ratio of the C. panzhihuaensis population is balanced. Additionally, there is a significant clustering effect in spatial
Yong‐Qiong Yang   +8 more
wiley   +1 more source

Acute symptoms of depression and traumatic stress in men and women who terminate pregnancy after the detection of fetal anomaly: A prospective observational study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
Abstract Objective To assess acute and long‐term stress in men and women after the detection of fetal anomalies leading to pregnancy termination. Design Prospective observational study. Setting Tertiary referral centre for fetal medicine. Population From the initial sample of 180 pregnant women with a fetal anomaly detected by ultrasound examination, a
Mona Bekkhus   +4 more
wiley   +1 more source

Differential gene expression in Chorthippus parallelus (Zetterstedt, 1821) (Orthoptera: Acrididae: Gomphocerinae) induced by Wolbachia infection

open access: yesInsect Science, EarlyView.
Distinct lineages of the grasshopper Chorthippus parallelus (Orthoptera: Acrididae) form a well‐known hybrid zone (HZ) in the Pyrenees mountain range; the Iberian endemism C. p. erythropus (Cpe) and the subspecies C. p. parallelus, (Cpp) widely distributed throughout the rest of Europe. Both subspecies differ in diverse traits, including the strains of
Patricia Jiménez‐Florido   +4 more
wiley   +1 more source

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