Results 81 to 90 of about 15,433 (199)

Age and Sex Effects on Blood Retrotransposable Element Expression Levels: Findings From the Population‐Based Rhineland Study

Aging Cell, EarlyView.
Retrotransposable element (RTE) expression increases with chronological and biological age and is negatively associated with heterochromatin regulators. Moreover, RTE expression shows sex‐specific differences, with higher levels in men and enrichment for immune‐related pathways.
Valentina Talevi, Hang‐Mao Lee, Dan Liu, Marc D. Beyer, Paolo Salomoni, Monique M. B. Breteler, N. Ahmad Aziz   +6 more
wiley   +1 more source

Molecular Insights Into the Natural History of Anal HSIL. [PDF]

J Med Virol
Jary A, van der Zee RP, Jongen V, Ter Braak TJ, Kim Y, Meijer CJLM, van Noesel CJM, de Vries HJC, van der Loeff MFS, Steenbergen RDM.   +9 more
europepmc   +1 more source

Persistence of Ancestral KhoeSan Mitochondrial Patterns in Contemporary South African Populations

Annals of Human Genetics, EarlyView.
Abstract Introduction Southern Africa has been inhabited by hunter‐gatherers for at least 20,000 years and has received diverse immigration flows in the last 2000 years. The original inhabitants have interacted with the pastoralist migrants from Eastern Africa (∼2000 ybp), followed by the southern Bantu migration arriving some 1000 ybp, and more ...
Maria Eugenia D'Amato, Peter Ristow, Michelle Livesey, Kirsty Heynes, Nicole Huber, Claudio Bravi, Anders J. Hansen, Walther Parson   +7 more
wiley   +1 more source

The Effect of Assisted Reproductive Technologies on Human Sex Ratios

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Modern assisted reproductive technology (ART), including pre‐implantation genetic testing for aneuploidy (PGT‐A), has opened new avenues in understanding early embryonic events and has simultaneously raised questions about the impact of ART itself on sex ratios.
Ektoras X. Georgiou, Yossi Mizrachi, Rebecca Kelley, Sharyn Stock‐Myer, John Stevens, David K. Gardner, Alex Polyakov   +6 more
wiley   +1 more source

Cytogenetic signatures favoring metastatic organotropism in colorectal cancer. [PDF]

Nat Commun
Golas MM, Gunawan B, Gutenberg A, Danner BC, Gerdes JS, Stadelmann C, Füzesi L, Liersch T, Sander B.   +8 more
europepmc   +1 more source

Gene–Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies

Allergy, EarlyView.
Atopic eczema is a complex trait resulting from multiple genetic and environmental factors. This study investigated evidence for interaction between 24 established eczema genetic risk variants and 18 environmental factors. One variant‐environmental pair showed nominally significant interaction in discovery, replication and meta‐analyses: early‐life dog
Marie Standl, Ashley Budu‐Aggrey, Luke J. Johnston, Martina S. Elias, S. Hasan Arshad, Peter Bager, Veronique Bataille, Helena Blakeway, Klaus Bønnelykke, Dorret Boomsma, Ben M. Brumpton, Mariona Bustamante Pineda, Archie Campbell, John A. Curtin, Anders Eliasen, João P. S. Fadista, Bjarke Feenstra, Trine Gerner, Carolina Medina‐Gomez, Sarah Grosche, Kristine B. Gutzkow, Anne‐Sofie Halling, Caroline Hayward, John Henderson, Esther Herrera‐Luis, John W. Holloway, Joukejan Hottenga, Jonathan O’B Hourihane, Chen Hu, Kristian Hveem, Amaia Irizar, Benedicte Jacquemi, Leon Jessen, Sara Kress, Ramesh J. Kurukulaaratchy, Susanne Lau, Sabrina Llop, Mari Løset, Ingo Marenholz, Dan Mason, Daniel L. McCartney, Mads Melbye, Erik Melén, Camelia Minica, Clare S. Murray, Tamar Nijsten, Luba M. Pardo, Suzanne Pasmans, Craig E. Pennell, Maria R. Rinnov, Gillian Santorelli, Tamara Schikowski, Darina Sheehan, Angela Simpson, Cilla Söderhäll, Laurent F. Thomas, Jacob P. Thyssen, Maties Torrent, Toos van Beijsterveldt, Alessia Visconti, Judith M. Vonk, Carol A. Wang, Cheng‐Jian Xu, Ali H. Ziyab, UK Translational Research Network in Dermatology, BIOMAP Consortium, Adnan Custovic, Paola Di Meglio, Liesbeth Duijts, Carsten Flohr, Alan D. Irvine, Gerard H. Koppelman, Young‐Ae Lee, Nick J. Reynolds, Catherine Smith, Sinéad M. Langan, Lavinia Paternoster, Sara J. Brown   +77 more
wiley   +1 more source

Optical genome mapping enhances cytogenetic analysis in recurrent miscarriage: confirmation of a suspected (1;10) chromosomal translocation. [PDF]

Mol Cytogenet
Del Águila MDM, Bernal M, Vílchez JR, Romero B, Castilla JA, Álvarez G, Clavero A, Poyatos A, Ruíz-Cabello F.   +8 more
europepmc   +1 more source

Genetically Determined Inflammation‐Related Proteins in Asthma and Type‐2 Signatures

Allergy, EarlyView.
This study investigates the association between genetic variation and inflammation‐related plasma proteins, and the differences in the proteins genetically determined between subjects with type‐2 signatures and/or asthma. Our findings suggest a strong contribution of genetic variation to the inflammation‐related proteome.
Natalia Hernandez‐Pacheco, Sophia Björkander, Simon Kebede Merid, Maura Kere, Ashish Kumar, Susanna Klevebro, Ida Mogensen, Sandra Ekström, Christer Janson, Lena Palmberg, Marianne van Hage, Anders Mälarstig, Anne‐Sophie Merritt, Göran Pershagen, Anna Bergström, Inger Kull, Jochen M. Schwenk, Erik Melén   +17 more
wiley   +1 more source

Clinical Value of MLPA for Prognostic Assessment of Chromosomal Rearrangements and DNA Methylation in Uveal Melanoma. [PDF]

Invest Ophthalmol Vis Sci
Soltysova A, Dvorska D, Ficek A, Pecimonova M, Samec M, Kasubova I, Horvathova Kajabova V, Demkova L, Babal P, Valaskova J, Dankova Z, Smolkova B, Furdova A.   +12 more
europepmc   +1 more source

Concordance and pathogenicity of copy number variants detected by non-invasive prenatal screening in 38,611 pregnant women without fetal structural abnormalities. [PDF]

Chin Med J (Engl)
Liu Y, Wang J, Wang L, Chen L, Xie D, Wang L, Liu S, Liu J, Bai T, Jing X, Deng C, Xia T, Cheng J, Xing L, Wei X, Luo Y, Zhou Q, Liu L, Zhu Q, Liu H.   +19 more
europepmc   +1 more source