Advanced Science, EarlyView.The origin and functional heterogeneity of pericytes in glioblastoma (GBM) remain unclear. This study identifies tumor‐originated pericytes (T‐PCs) and normal‐originated pericytes as two distinctive populations in human GBM using single‐cell RNA‐sequencing.
Cuiying Chu +16 more
wiley +1 more source
Sex chromosomes in willows [PDF]
, 2016 Sexual reproduction is found in most eukaryotes and has in the majority of animal species led to the evolution of separate sexes. In contrast, only 5-6% of all angiospersms are dioecious with female and male flowers on separate individuals. Interestingly,
Pucholt, Pascal
core
Advanced Science, EarlyView.This study elucidates a molecular mechanism enabling species coexistence between parasitoid wasps, showing how Asobara japonica uses a set of novel venom proteins to delay host development and exploit older hosts, thereby achieving temporal niche partitioning with Leptopilina drosophilae. Abstract Interspecific competition can drive species coexistence
Junwei Zhang +11 more
wiley +1 more source
XX/XY Sex Chromosomes in the South American Dwarf Gecko (\u3cem\u3eGonatodes humeralis\u3c/em\u3e) [PDF]
, 2018 Sex-specific genetic markers identified using restriction site-associated DNA sequencing, or RADseq, permits the recognition of a species’ sex chromosome system in cases where standard cytogenetic methods fail.
Gamble, Tony +6 more
core +1 more source
Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids
Advanced Science, EarlyView.To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun +9 more
wiley +1 more source
Signatures of replication timing, recombination, and sex in the spectrum of rare variants on the human X chromosome and autosomes [PDF]
, 2019 Ipsita Agarwal, Molly Przeworski
openalex +1 more source
Polymorphism at a Sex-Linked Transcription Cofactor in European Tree Frogs ( Hyla arborea ): Sex-Antagonistic Selection or Neutral Processes? [PDF]
, 2018 Nascent sex chromosomes offer a unique opportunity to investigate the evolutionary fate of genes recently trapped in non-recombining segments. A house-keeping gene (MED15) was recently shown to lie on the nascent sex-chromosomes of the European tree frog
Dufresnes, Christophe +4 more
core
Identifying Key Questions and Challenges in Microchimerism Biology
Advanced Science, EarlyView.This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua +31 more
wiley +1 more source
Differential Divergence of Three Human Pseudoautosomal Genes and Their Mouse Homologs: Implications for Sex Chromosome Evolution [PDF]
, 2001 Fernando Gianfrancesco +9 more
openalex +1 more source
ZW sex-chromosome evolution and contagious parthenogenesis in Artemia brine shrimp [PDF]
, 2022 Marwan Elkrewi +10 more
openalex +1 more source