Results 1 to 10 of about 553,309 (213)
X chromosome inactivation, X-linked disorders, and cancer. [PDF]
Front GenetX chromosome inactivation is an essential process that compensates for gene dosage differences between men and women. During early embryogenesis, one of the two X chromosomes in females is randomly selected for transcriptional silencing, inactivating ...
Salas-Labadía C +6 more
europepmc +2 more sources
Prenatal diagnosis and clinical evaluation of fetuses with structural X chromosome abnormalities: a ten-year single-center retrospective study. [PDF]
BMC Med GenomicsBackground Structural X chromosome abnormalities are rare conditions and pose great challenges in prenatal genetic counseling. The present study aimed to identify and investigate the pregnancy outcome of fetuses with X chromosome structural abnormalities
Zhang L +4 more
europepmc +2 more sources
The human inactive X chromosome modulates expression of the active X chromosome
Cell Genomics, 2023 Summary: The “inactive” X chromosome (Xi) has been assumed to have little impact, in trans, on the “active” X (Xa). To test this, we quantified Xi and Xa gene expression in individuals with one Xa and zero to three Xis.
Adrianna K. San Roman +21 more
doaj +1 more source
A ROLE FOR CELLULAR IMMUNITY IN EARLY POSTPARTUM PERIOD
Медицинская иммунология, 2021 The functioning of the secretory organs is closely related to the activity of the immune system. As is well known, this participation is manifested in the fact that at certain stages of activity, the lymphoid cells migrating to the organ can be involved ...
N. A. Panova, V. G. Skopichev
doaj +1 more source
Assessment of external risk factors of hepatocellular cancer development and markers of genetic predisposition to its development in the ethnic group of yakut - men [PDF]
Терапевтический архив, 2020 Aim. To establish the main external and genetically determined risk factors for the development of hepatocellular cancer in the ethnic group of male Yakuts living in the Republic of Sakha (Yakutia) [RS (Y)] in the epidemiologically unfavorable conditions
N D Yushchuk +8 more
doaj +1 more source
Frontiers in Genetics, 2021 Altered microRNA expression patterns in bronchial brushings from people with versus without cystic fibrosis (CF) relate to functional changes and disease pathophysiology.
Paul J. McKiernan +4 more
doaj +1 more source
Memories of an X-chromosome [PDF]
Stem Cell Investigation, 2017 Peer ...
Lamas Toranzo, Ismael +2 more
openaire +3 more sources
X chromosome and suicide [PDF]
Molecular Psychiatry, 2009 Suicide completion rates are significantly higher in males than females in most societies. Although gender differences in suicide rates have been partially explained by environmental and behavioral factors, it is possible that genetic factors, through differential expression between genders, may also help explain gender moderation of suicide risk. This
L M, Fiori +3 more
openaire +2 more sources
Immunoglobulins and the X-chromosome [PDF]
BMJ, 1969 Serum levels of immunoglobulins (Ig) G, M, and A were determined in 28 women with an additional X-chromosome (XXX), and in equal numbers of age-matched normal women and men. Mean IgM levels were found to be highest in the XXX group, intermediate in normal women, and lowest in men; these differences were statistically significant.
K, Rhodes +3 more
openaire +2 more sources
Association of X Chromosome Aberrations with Male Infertility
Acta Medica Bulgarica, 2021 Male infertility is caused by spermatogenetic failure, clinically noted as oligoor azoospermia. Approximately 20% of infertile patients carry a genetic defect.
Xharra S. +5 more
doaj +1 more source