Early events in the evolution of the Silene latifolia Y chromosome: Male specialization and recombination arrest [PDF]
, 2007 Understanding the origin and evolution of sex chromosomes requires studying recently evolved X-Y chromosome systems such as those in some flowering plants.
Georgiev, Sevdalin +8 more
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Escapees on the X chromosome [PDF]
Proceedings of the National Academy of Sciences, 1999 In many organisms, differentiation of the sex chromosome complement resulted in the coordinated regulation of genes on whole chromosomes to equalize gene expression between the sexes. In mammals, X inactivation evolved to restore equal expression of X-linked genes in males and females (1).
openaire +2 more sources
A family case of fertile human 45,X,psu dic(15;Y) males [PDF]
, 2006 We report on a familial case including four male probands from three generations with a 45,X,psu dic(15;Y)(p11.2;q12) karyotype. 45,X is usually associated with a female phenotype and only rarely with maleness, due to translocation of small Y chromosomal
P.M. Gopinath +17 more
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A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse. [PDF]
, 2012 Intragenomic conflicts arise when a genetic element favours its own transmission to the detriment of others. Conflicts over sex chromosome transmission are expected to have influenced genome structure, gene regulation, and speciation.
Shantha K. Mahadevaiah (94714) +17 more
core +1 more source
X chromosome control of meiotic chromosome synapsis in mouse inter-subspecific hybrids. [PDF]
PLoS Genetics, 2014 Hybrid sterility (HS) belongs to reproductive isolation barriers that safeguard the integrity of species in statu nascendi. Although hybrid sterility occurs almost universally among animal and plant species, most of our current knowledge comes from the ...
Tanmoy Bhattacharyya +8 more
doaj +1 more source
Identification of novel Y chromosome encoded transcripts by testis transcriptome analysis of mice with deletions of the Y chromosome long arm. [PDF]
, 2005 BACKGROUND The male-specific region of the mouse Y chromosome long arm (MSYq) is comprised largely of repeated DNA, including multiple copies of the spermatid-expressed Ssty gene family.
Ojarikre, Obah A. +28 more
core +7 more sources
Cell lineage specific distribution of H3K27 trimethylation accumulation in an in vitro model for human implantation [PDF]
, 2012 Female mammals inactivate one of their two X-chromosomes to compensate for the difference in gene-dosage with males that have just one X-chromosome. X-chromosome inactivation is initiated by the expression of the non-coding RNA Xist, which coats the X ...
Weimar, Charlotte H. E. +34 more
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Statistical mechanics of genome regulation: the case of X chromosome inactivation [PDF]
, 2010 The aim of my PhD research project was to discover the mechanisms behind X Chromosome Inactivation (XCI) one of the most intriguing issues of the current mammalian Biology.
Scialdone, Antonio
core +1 more source
Deciphering the Role of the Barr Body in Malignancy: An insight into head and neck cancer
Sultan Qaboos University Medical Journal, 2018 X chromosome inactivation is the epitome of epigenetic regulation and long non-coding ribonucleic acid function. The differentiation status of cells has been ascribed to X chromosome activity, with two active X chromosomes generally only observed in ...
Deepti Sharma +4 more
doaj +1 more source
Deficiency in the multicopy Sycp3-like X-linked genes Slx and Slxl1 causes major defects in spermatid differentiation. [PDF]
, 2010 The human and mouse sex chromosomes are enriched in multicopy genes required for postmeiotic differentiation of round spermatids into sperm. The gene Sly is present in multiple copies on the mouse Y chromosome and encodes a protein that is required for ...
Ojarikre, Obah A. +19 more
core +1 more source