Results 41 to 50 of about 553,309 (213)

A History of the Discovery of Random X Chromosome Inactivation in the Human Female and its Significance

Rambam Maimonides Medical Journal, 2011
Genetic determinants of sex in placental mammals developed by the evolution of primordial autosomes into the male and female sex chromosomes. The Y chromosome determines maleness by the action of the gene SRY, which encodes a protein that initiates a ...
Sophia Balderman, Marshall A. Lichtman
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Accelerated adaptive evolution on a newly formed X chromosome.

PLoS Biology, 2009
Sex chromosomes originated from ordinary autosomes, and their evolution is characterized by continuous gene loss from the ancestral Y chromosome. Here, we document a new feature of sex chromosome evolution: bursts of adaptive fixations on a newly formed ...
Doris Bachtrog, Jeffrey D Jensen, Zhi Zhang   +2 more
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Neocentric X-chromosome in a girl with Turner-like syndrome

Molecular Cytogenetics, 2012
Background Neocentromeres are rare human chromosomal aberrations in which a new centromere has formed in a previously non-centromeric location. We report the finding of a structurally abnormal X chromosome with a neocentromere in a 15-year-old girl with ...
Hemmat Morteza, Wang Boris T, Warburton Peter E, Yang Xiaojing, Boyar Fatih Z, El Naggar Mohammed, Anguiano Arturo   +6 more
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Amenorréia e anormalidades do cromossomo X Amenorrhea and X chromosome abnormalities

Revista Brasileira de Ginecologia e Obstetrícia, 2008
OBJETIVO: correlacionar as manifestações clínicas de pacientes com amenorréia e anormalidades do cromossomo X. MÉTODOS: realizou-se uma análise retrospectiva dos achados clínicos e laboratoriais das pacientes com amenorréia e anormalidades do cromossomo ...
Rafael Fabiano Machado Rosa, Raquel Papandreus Dibi, Jamile dos Santos Picetti, Rosana Cardoso Manique Rosa, Paulo Ricardo Gazzola Zen, Carla Graziadio, Giorgio Adriano Paskulin   +6 more
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X chromosome: expression and escape. [PDF]

PLoS Genetics, 2009
John Parsch
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Dynamics of the two heterochromatin types during imprinted X chromosome inactivation in vole Microtus levis.

PLoS ONE, 2014
In rodent female mammals, there are two forms of X-inactivation - imprinted and random which take place in extraembryonic and embryonic tissues, respectively.
Evgeniya A Vaskova, Elena V Dementyeva, Alexander I Shevchenko, Sophia V Pavlova, Elena V Grigor'eva, Antonina I Zhelezova, John L Vandeberg, Suren M Zakian   +7 more
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Tissue-specific features of the X chromosome and nucleolus spatial dynamics in a malaria mosquito, Anopheles atroparvus.

PLoS ONE, 2017
Spatial organization of chromosome territories is important for maintenance of genomic stability and regulation of gene expression. Recent studies have shown tissue-specific features of chromosome attachments to the nuclear envelope in various organisms ...
Semen M Bondarenko, Gleb N Artemov, Igor V Sharakhov, Vladimir N Stegniy   +3 more
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X chromosome and autosomal recombination are differentially sensitive to disruptions in SC maintenance [PDF]

, 2019
Katherine Kretovich Billmyre, Cori K. Cahoon, G. Matthew Heenan, Emily R. Wesley, Zulin Yu, Jay R. Unruh, Satomi Takeo, R. Scott Hawley   +7 more
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Varying levels of X chromosome coalescence in female somatic cells alters the balance of X-linked dosage compensation and is implicated in female-dominant systemic lupus erythematosus

Scientific Reports, 2019
The three-dimensional organization of the genome in mammalian interphase nuclei is intrinsically linked to the regulation of gene expression. Whole chromosome territories and their encoded gene loci occupy preferential positions within the nucleus that ...
Agnieszka I. Laskowski, Daniel S. Neems, Kyle Laster, Chelsee Strojny-Okyere, Ellen L. Rice, Iwona M. Konieczna, Jessica H. Voss, James M. Mathew, Joseph R. Leventhal, Rosalind Ramsey-Goldman, Erica D. Smith, Steven T. Kosak   +11 more
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Movement of X Chromosome in Epileptic Cortex

Pediatric Neurology Briefs, 1989
Chronic uncontrolled seizure activity was linked to specific positional changes of the X chromosome in neurons of cortical seizure foci from both male and female patients at Yale University School of Medicine, New Haven, Connecticut.
J Gordon Millichap
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