Results 51 to 60 of about 553,309 (213)

Demasculinization of the Anopheles gambiae X chromosome

open access: yesBMC Evolutionary Biology, 2012
Background In a number of organisms sex-biased genes are non-randomly distributed between autosomes and the shared sex chromosome X (or Z). Studies on Anopheles gambiae have produced conflicting results regarding the underrepresentation of male-biased ...
Magnusson Kalle   +6 more
doaj   +1 more source

Population variability in X-chromosome inactivation across 10 mammalian species

open access: yesNature Communications
One of the two X-chromosomes in female mammals is epigenetically silenced in embryonic stem cells by X-chromosome inactivation. This creates a mosaic of cells expressing either the maternal or the paternal X allele.
Jonathan M. Werner   +2 more
doaj   +1 more source

BRCA1-mediated repression of select X chromosome genes

open access: yesJournal of Translational Medicine, 2004
Recently BRCA1 has been implicated in the regulation of gene expression from the X chromosome. In this study the influence of BRCA1 on expression of X chromosome genes was investigated.
Ropers H Hilger   +9 more
doaj   +1 more source

The toll like receptor 7 pathway and the sex bias of systemic lupus erythematosus

open access: yesFrontiers in Immunology
Systemic lupus erythematosus (SLE) predominately affects women with a ratio of females-to-males of about 9:1. The complement of sex chromosomes may play and important role in the mechanism of the sex bias.
R. Hal Scofield   +6 more
doaj   +1 more source

Nonrandom X Chromosome Inactivation Is Influenced by Multiple Regions on the Murine X Chromosome [PDF]

open access: bronze, 2012
Joanne L. Thorvaldsen   +3 more
openalex   +1 more source

Dynamic dosage changes in X-linked transposable elements during mammalian dosage compensation

open access: yesNature Communications
In mammals, X-linked dosage compensation involves X-chromosome inactivation to balance X chromosome dosage between males and females, and hyperactivation of the remaining X-chromosome (Xa-hyperactivation) to achieve X-autosome balance in both sexes ...
Chunyao Wei   +5 more
doaj   +1 more source

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