Results 11 to 20 of about 568,444 (262)
Memories of an X-chromosome [PDF]
Stem Cell Investigation, 2017 Peer ...
Lamas Toranzo, Ismael +2 more
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X chromosome and suicide [PDF]
Molecular Psychiatry, 2009 Suicide completion rates are significantly higher in males than females in most societies. Although gender differences in suicide rates have been partially explained by environmental and behavioral factors, it is possible that genetic factors, through differential expression between genders, may also help explain gender moderation of suicide risk. This
L M, Fiori +3 more
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Immunoglobulins and the X-chromosome [PDF]
BMJ, 1969 Serum levels of immunoglobulins (Ig) G, M, and A were determined in 28 women with an additional X-chromosome (XXX), and in equal numbers of age-matched normal women and men. Mean IgM levels were found to be highest in the XXX group, intermediate in normal women, and lowest in men; these differences were statistically significant.
K, Rhodes +3 more
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Monosomy for the X chromosome [PDF]
Chromosome Research, 2009 Dosage compensation serves to equalize X chromosome gene expression in mammalian males and females and involves extensive silencing of the 2nd X chromosome in females. If dosage compensation mechanisms completely suppressed the 2nd X chromosome, then actual physical loss of this "eXtra" chromosome should have few consequences.
Carolyn A, Bondy, Clara, Cheng
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X-Chromosome Inactivation [PDF]
Current Biology, 1994 In female mammals, all X chromosomes except one are transcriptionally inactivated early in embryonic development. This is known as X-chromosome inactivation and is a form of dosage compensation, giving equal dosage of the products of X-linked genes in males and females. The mechanism is of considerable interest as an example of differential behavior of
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G3: Genes, Genomes, Genetics, 2020 Mouse sex chromosomes are enriched for co-amplified gene families, present in tens to hundreds of copies. Co-amplification of Slx/Slxl1 on the X chromosome and Sly on the Y chromosome are involved in dose-dependent meiotic drive, however the role of ...
Martin F. Arlt +4 more
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Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome
Nature Communications, 2016 It is unclear how often genetic mosaicism of chromosome X arises. Here, the authors examine women with cancer and cancer-free controls and show that X chromosome mosaicism occurs more frequently than on autosomes, especially on the inactive X chromosome,
Mitchell J. Machiela +175 more
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Deciphering the Role of the Barr Body in Malignancy: An insight into head and neck cancer
Sultan Qaboos University Medical Journal, 2018 X chromosome inactivation is the epitome of epigenetic regulation and long non-coding ribonucleic acid function. The differentiation status of cells has been ascribed to X chromosome activity, with two active X chromosomes generally only observed in ...
Deepti Sharma +4 more
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X chromosome inactivation during Drosophila spermatogenesis. [PDF]
PLoS Biology, 2007 Genes with male- and testis-enriched expression are under-represented on the Drosophila melanogaster X chromosome. There is also an excess of retrotransposed genes, many of which are expressed in testis, that have "escaped" the X chromosome and moved to ...
Winfried Hense +2 more
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Turkish Journal of Hematology, 2010 We report herein a very rare case of acute lymphoblastic leukemia having a chromosomal constitution of 48,XY,+X,+5,t(9;22)(q34;q11) in the bone marrow.
Burak Durmaz +5 more
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