Results 191 to 200 of about 86,282 (258)

Extreme heterochiasmy and high rates of sex-reversed recombination result in large yet homomorphic sex chromosomes in the Emei moustache toad. [PDF]

Genome Res
Xie S, Li J, Chen W, Fong LJM, Huang C, Feng Y, Ai Q, Zhao M, Mank JE, Wu H.   +9 more
europepmc   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Why should we study plant sex chromosomes? [PDF]

Plant Cell
Charlesworth D, Harkess A.
europepmc   +1 more source

Antiviral regulator TRIM25 as a prognostic marker of better survival in Merkel cell carcinoma: Association with MCPyV status

International Journal of Cancer, EarlyView.
What's New? TRIM25 is known for its role in antiviral immunity and association with poor prognosis in various cancers. This study reveals an association between high TRIM25 expression and Merkel cell polyomavirus positivity in Merkel cell carcinoma.
Klaus W. Fagerstedt, Sami Kilpinen, Johanna Arola, Benjamin Z. Sundqvist, Tom Böhling, Leif C. Andersson, Harri Sihto   +6 more
wiley   +1 more source

Evolution of ZW Sex Chromosomes in <i>Ptyas</i> Snakes (Reptilia, Colubridae): New Insights from a Molecular Cytogenetic Perspective. [PDF]

Int J Mol Sci
Setti PG, Ezaz T, Deon GA, Utsunomia R, Tanomtong A, Ditcharoen S, Donbundit N, Sumontha M, Seetapan K, Buasriyot P, Pinthong K, Thongnetr W, Dos Santos N, Porto-Foresti F, Liehr T, Cioffi MB.   +15 more
europepmc   +1 more source

Risk of childhood and adolescent, and young adult cancer in offspring of men with testicular cancer: A Danish nationwide study

International Journal of Cancer, EarlyView.
What's New? Testicular germ cell cancer (TC), the most common solid tumor among young men in Western countries, has survival rates exceeding 95 percent, allowing most survivors to pursue fatherhood. Concerns remain, however, about cancer risk in offspring, given potential mutagenic effects incurred during treatment for TC.
Mikkel Bandak, Susanne Rosthøj, Gitte Lerche Aalborg, Jakob Lauritsen, Aleksander Giwercman, Hege Sagstuen Haugnes, Gedske Daugaard, Allan Jensen   +7 more
wiley   +1 more source

Retraction: Sheltering of deleterious mutations explains the stepwise extension of recombination suppression on sex chromosomes and other supergenes. [PDF]

PLoS Biol
PLOS Biology Editors.
europepmc   +1 more source

ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance

International Journal of Cancer, EarlyView.
What's New? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado, Angelica Macauda, Antonio José Cabrera‐Serrano, Hauke Thomsen, Murat Güler, Rob Ter Horst, Bethany van Guelpen, Pavel Vodicka, Stefano Landi, Subhayan Chattopadhyay, Pelin Ünal, Lucía Ruiz‐Durán, Delphine Casabonne, Hartmut Goldschmidt, Istemi Serin, María Carretero‐Fernández, Elena Cabezudo, Fernando Reyes‐Zurita, Aaron D. Norman, Ramón García‐Sanz, Gabriele Capurso, Per Hoffmann, Ulrika Pettersson‐Kymmer, Francisco Jiménez‐Romera, S. Vincent Rajkumar, Niels Weinhold, Ludmila Vodickova, Christian Langer, Angelika Stein, Abdulkadir Karismaz, Victor Moreno, Markus M. Nöthen, Karl‐Heinz Jöckel, Francesca Tavano, Joaquín Martínez‐López, Shaji K. Kumar, Juan Francisco Gutiérrez‐Bautista, Daniela Basso, Florentin Späth, Yolanda Benavente, Michelle A. T. Hildebrandt, Börge Schmidt, Tereza Sevcikova, Rui Manuel Vieira Reis, Yang Li, Miguel Ángel López‐Nevot, Mihai G. Netea, Daniele Campa, Alyssa Clay‐Gilmour, Susan L Slager, Kari Hemminki, Celine M Vachon, Asta Försti, Federico Canzian, Juan Sainz   +54 more
wiley   +1 more source

Red Deer Resequencing Reveals the Importance of Sex Chromosomes for Reconstructing Late Quaternary Events. [PDF]

Mol Biol Evol
de Jong MJ, Anaya G, Niamir A, Pérez-González J, Broggini C, Del Pozo AM, Nebenfuehr M, de la Peña E, Ruiz-Olmo J, Seoane JM, Vedel G, Barboiron A, Bartoš L, Buzan E, Carden RF, Darchiashvili G, Frantz AC, Gačić D, Gérard A, Gort-Esteve A, Guillaumat E, Hantschmann A, Hemami MR, Höglund J, de Jong JF, Karaiskou N, Kerdikoshvili N, Kern C, Konjevic D, Koubek P, Krojerová-Prokešová J, McDevitt AD, Merker S, Pellerin M, Pfenninger M, Røed KH, Saint-Andrieux C, Sarigol F, Sykut M, Triantafyllidis A, Pemberton J, Saarma U, Iacolina L, Niedziałkowska M, Zachos FE, Carranza J, Janke A.   +46 more
europepmc   +1 more source