Results 181 to 190 of about 1,541,356 (256)

Autosomally-encoded segregation distortion of sex chromosomes. [PDF]

Proc Biol Sci
Greenberg NL, Patten MM, Schenkel MA.
europepmc   +1 more source

Pedagogical introductions to sex and gender diversity in anatomy: Exploring student perspectives

Anatomical Sciences Education, EarlyView.
Abstract Anatomical education has historically relied on binary terminology, reinforcing the conflation of sex, gender, and gender identity through long‐standing social and linguistic norms. To better include gender and sex diverse students and to respect the delineations between gender and sex, educators are incorporating diversity into their courses ...
Charlie W. Brake, Charys M. Martin
wiley   +1 more source

Multiple Origins of Sex Chromosomes in Nothobranchius Killifishes. [PDF]

Mol Ecol
Hospodářská M, Mora P, Voleníková AC, Al-Rikabi A, Altmanová M, Simanovsky SA, Tolar N, Pavlica T, Janečková K, Štundlová J, Bobryshava K, Jankásek M, Hiřman M, Liehr T, Reichard M, Krysanov EY, Ráb P, Englert C, Nguyen P, Sember A.   +19 more
europepmc   +1 more source

Clinical and Genetic Factors Associated With Regression in Children With Autism Spectrum Disorders

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition with complex genetic and environmental underpinnings. A clinically significant subset of children with ASD experience developmental regression (regASD), characterized by the acute loss of previously acquired skills. The mechanisms, predictors, and molecular basis of
Anna Maruani, Emma Delclaud, Paul Bruzeau, Richard Delorme, Anne‐Claude Tabet, Valérie Vantalon, Jonathan Levy, Pierre Ellul   +7 more
wiley   +1 more source

Structural and evolutionary features of red algal UV sex chromosomes. [PDF]

Genome Biol
Lipinska AP, Cossard G, Epperlein P, Woertwein T, Molinier C, Godfroy O, Carli S, Ayres-Ostrock L, Lavaut E, Marchi F, Mauger S, Destombe C, Oliveira MC, Plastino EM, Krueger-Hadfield SA, Guillemin ML, Valero M, Coelho SM.   +17 more
europepmc   +1 more source

Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen, Mathilde Rønne Koch, Cecilie Utke Rank, Christen Lykkegaard Andersen, Allan Weimann, Maria Thastrup, Tianwu Yang, Trine Meldgaard Lund, Ib Jarle Christensen, Flemming Nielsen, Tore Bjerregaard Stage, Sara Bisgaard Jensen, Mette Klarskov Andersen, Kjeld Schmiegelow, Kim Dalhoff   +14 more
wiley   +1 more source

Male and female genomes of millipede (<i>Trigoniulus corallinus</i>) and identification of sex chromosomes. [PDF]

iScience
Chen Y, Nong W, So WL, Qu Z, Gaitan-Espitia JD, Kai ZP, Bendena WG, Lau KF, Hui JHL.   +8 more
europepmc   +1 more source

Case‐malformed signal detection and prioritisation using EUROmediCAT data for pharmacovigilance in pregnancy

British Journal of Clinical Pharmacology, EarlyView.
Aim Many women take medications during pregnancy. However, the risk to the fetus from most medications is uncertain. Congenital anomalies are one of the leading causes of infant death and contribute to long‐term disability. Signal detection methods can be used to systematically identify possible medication–anomaly associations that require further ...
Hannah Johnson, Helen Dolk, Maria Loane, Christine Damase‐Michel, Joanne Given, Hedvig Nordeng, Jorieke E. H. Bergman, Iain Carey, Elly Den Hond, Ester Garne, Florence Rouget, Lea Bruneau, Isabelle Monier, Anke Rissmann, Mary O'Mahony, Miriam Gatt, Renée Lutke, Joanna Sichitiu, Elisa Ballardini, Alessio Coi, Clara Cavero Carbonell, David Tucker, Joan Morris   +22 more
wiley   +1 more source

Origin and evolutionary trajectories of brown algal sex chromosomes. [PDF]

Nat Ecol Evol
Barrera-Redondo J, Lipinska AP, Liu P, Dinatale E, Cossard G, Bogaert K, Hoshino M, Craig RJ, Avia K, Leiria G, Avdievich E, Liesner D, Luthringer R, Godfroy O, Heesch S, Nehr Z, Brillet-Guéguen L, Peters AF, Hoarau G, Pearson G, Aury JM, Wincker P, Denoeud F, Cock JM, Haas FB, Coelho SM.   +25 more
europepmc   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source