Results 1 to 10 of about 47,561 (246)

Dental caries shallow-layer microbe harvest and data display method shows taxa pre-harvest spatial positions, absolute and relative abundance and diversity related to lesion pulpal depth

open access: yesJournal of Oral Microbiology
Background Molecular identification of dental caries microbes is advancing rapidly, yet sampling methods remain outdated and imprecise.Objective To refine microbe sample harvesting and preserve taxa pre-harvest spatial positions relative to lesion pulpal
Rella P. Christensen   +4 more
doaj   +1 more source

Perineural invasion in pancreatic cancer: proteomic analysis and in vitro modelling

open access: yesMolecular Oncology, 2019
Perineural invasion (PNI) is a common and characteristic feature of pancreatic ductal adenocarcinoma (PDAC) that is associated with poor prognosis, tumor recurrence, and generation of pain.
Wasfi Alrawashdeh   +9 more
doaj   +1 more source

Using the Parafilm-assisted Microdissection (PAM) Method to Sample Rodent Nucleus Accumbens

open access: yesBio-Protocol, 2020
Microdissection techniques are very important for anatomical and functional studies focused on neuroscience, where it is often necessary microdissect specific brain areas to perform molecular or anatomical analyses. The parafilm®-assisted microdissection
Marco Pagliusi Jr.   +5 more
doaj   +1 more source

Microdissection of lampbrush chromosomes as an approach for generation of locus-specific FISH-probes and samples for high-throughput sequencing

open access: yesBMC Genomics, 2016
Over the past two decades, chromosome microdissection has been widely used in diagnostics and research enabling analysis of chromosomes and their regions through probe generation and establishing of chromosome- and chromosome region-specific DNA ...
A. Zlotina   +4 more
semanticscholar   +1 more source

Comparison of Tissue Repair with Different Types of Microdissection Tips: A Randomized Histomorphometric Evaluation in Rats

open access: yesBioengineering
The aim of the study was to compare tissue repair of incisions made using different microdissection electrocautery tips in an in vivo animal model. Skin incisions were made, including the subcutaneous tissue, in 30 adult Wistar rats using four types of ...
Ana Luiza Vila Verde Brunelli   +6 more
doaj   +1 more source

Optimizing Frozen Sample Preparation for Laser Microdissection: Assessment of CryoJane Tape-Transfer System®.

open access: yesPLoS ONE, 2013
Laser microdissection is an invaluable tool in medical research that facilitates collecting specific cell populations for molecular analysis. Diversity of research targets (e.g., cancerous and precancerous lesions in clinical and animal research, cell ...
Yelena G Golubeva   +2 more
doaj   +1 more source

HER-2/neu amplification testing in breast cancer by Multiplex Ligation-dependent Probe Amplification: influence of manual- and laser microdissection

open access: yesBMC Cancer, 2009
Background Accurate assessment of HER-2/neu status is crucial for proper prognostic information and to offer direct appropriate treatment for breast cancer patients.
Ezendam Chantal   +3 more
doaj   +1 more source

The controversial existence of the human superior fronto-occipital fasciculus: Connectome-based tractographic study with microdissection validation

open access: yesHuman Brain Mapping, 2015
The superior fronto‐occipital fasciculus (SFOF), a long association bundle that connects frontal and occipital lobes, is well‐documented in monkeys but is controversial in human brain. Its assumed role is in visual processing and spatial awareness.
Antonio Meola   +4 more
semanticscholar   +1 more source

Fresh Versus Frozen Testicular Sperm Samples in Microdissection Testicular Sperm Extraction Intracytoplasmic Sperm Injection Treatment

open access: yesGynecology Obstetrics & Reproductive Medicine, 2017
Objective: The present study aims to compare the clinical outcomes of fresh versus frozen testicular samples in patients with non-obstructive azoospermia who would undergo intracytoplasmic sperm injection procedure.
Şafak Hatırnaz   +3 more
doaj   +1 more source

Impact of Upfront Cellular Enrichment by Laser Capture Microdissection on Protein and Phosphoprotein Drug Target Signaling Activation Measurements in Human Lung Cancer: Implications for Personalized Medicine

open access: yesPROTEOMICS - Clinical Applications, 2015
The aim of this study was to evaluate whether upfront cellular enrichment via laser capture microdissection (LCM) is necessary for accurately quantifying predictive biomarkers in nonsmall cell lung cancer tumors.
Baldelli Elisa   +8 more
semanticscholar   +1 more source

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