Results 271 to 280 of about 2,299,084 (348)

Isolation of a sex chromosome-specific DNA sequence in the medaka, Oryzias latipes.

, 1997
Masaru Matsuda, Takehiko Kusama, Takashi Oshiro, Yasuyuki Kurihara, Satoshi Hamaguchi, Mitsuru Sakaizumi   +5 more
openalex   +2 more sources

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Variation in adult sex ratios in tetrapods is linked to sex chromosomes through mortality differences between males and females. [PDF]

PLoS Biol
Pipoly I, Bókony V, Gaillard JM, Lemaître JF, Székely T, Liker A.   +5 more
europepmc   +1 more source

ISOMORPHIC SEX CHROMOSOMES, AUTOSOMAL HETEROMORPHISM, AND TELOMERIC ASSOCIATIONS IN THE GREY HAMSTER OF ARMENIA, CRICETULUS MIGRATORIUS, PALL

, 2009
George Yerganian, SIMON PAPOYAN
openalex   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Reproductive hormones and sex chromosomes drive sex differences in the sleep-wake cycle. [PDF]

Front Neurosci
Ralston M, Ehlen JC, Paul K.
europepmc   +1 more source

Cardamonin Commands the Colonic Metabolite Columbianetin Acetate to Compete Against LPS in Binding HMGB1 in the Kidney, Preventing Lipopolysaccharide‐Induced Renal Tubular Pyroptosis

Food Frontiers, EarlyView.
Cardamonin upregulate sd the intestinal metabolite columbianetin acetate, which competitively bound HMGB1 to prevent LPS‐induced renal tubular cell pyroptosis (the figure is created with BioRender). ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the
Zihui Zhou, Xuechun Sun, Jian Zhou, Huali Meng, Pengfei Fan, Yufeng Chu, Hao Wu   +6 more
wiley   +1 more source

Sexy ways: approaches to studying plant sex chromosomes. [PDF]

J Exp Bot
Hobza R, Bačovský V, Čegan R, Horáková L, Hubinský M, Janíček T, Janoušek B, Jedlička P, Kružlicová J, Kubát Z, Rodríguez Lorenzo JL, Novotná P, Hudzieczek V.   +12 more
europepmc   +1 more source

Identification of Cathepsin H and Metabolic Traits as Potential Biomarkers for Lung Cancer by Mendelian Randomization and Single‐Cell Transcriptomics

Advanced Genetics, EarlyView.
This study explores the link between CTSH and lung cancer, covering global trends in lung cancer and hyperglycemia, MR analysis of CTSH and 233 metabolic traits, and scRNA analysis, along with multi‐level validation of CTSH expression in LUAD. These findings offer valuable insights into lung cancer biology and provide new perspectives for biomarker ...
Chenghu Song, Weici Liu, Zhao He, Jiwei Liu, Ruixin Wang, Lei Wu, Yize Wang, Mingfeng Zheng, Dong Tian, Wenjun Mao   +9 more
wiley   +1 more source

Evolution of ZW Sex Chromosomes in <i>Ptyas</i> Snakes (Reptilia, Colubridae): New Insights from a Molecular Cytogenetic Perspective. [PDF]

Int J Mol Sci
Setti PG, Ezaz T, Deon GA, Utsunomia R, Tanomtong A, Ditcharoen S, Donbundit N, Sumontha M, Seetapan K, Buasriyot P, Pinthong K, Thongnetr W, Dos Santos N, Porto-Foresti F, Liehr T, Cioffi MB.   +15 more
europepmc   +1 more source