Results 101 to 110 of about 973,816 (336)
Germ line control of female sex determination in zebrafish [PDF]
, 2008 A major transition during development of the gonad is commitment from an undifferentiated “bi-potential” state to ovary or testis fate. In mammals, the oogonia of the developing ovary are known to be important for folliculogenesis.
Nüsslein-Volhard, Christiane +1 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
FishesThe increased availability of reference genome assemblies of sharks and rays has contributed greatly to our understanding of their biology, including their sex-determination mechanisms.
Szu-Hsuan Lee +2 more
doaj +1 more source
Avian sex determination and aromatase gene [PDF]
, 2015 Sex is the most important exchange method of the genetic information in eukaryotes. Sex determination mechanism is varied depending on the species, however, sex differentiation mechanism in vertebrates are basically similar. Sex determination of birds is
Kudo, Toshiyuki
core
BMI-For-Age Cut-Off as an Indicator of Adiposity among In-School Children (Age 4-11 Years) in Obio/Akpor LGA, Rivers State, Nigeria [PDF]
, 2017 Background: Childhood overweight and obesity has been an issue of great concern to developing and developed nation where as degenerative underweight has ravaged the underdeveloped and war turn countries.
Aigbogun EO Jr, Ibeachu PC, Ikechukwu E
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Female-to-male sex reversal in mice caused by transgenic overexpression of Dmrt1 [PDF]
, 2015 Genes related to Dmrt1, which encodes a DNA-binding DM domain transcription factor, act as triggers for primary sex determination in a broad range of metazoan species.
Koopman, Peter +3 more
core +2 more sources
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Identification of the key stages for sex determination in the silkworm, Bombyx mori [PDF]
, 2013 In general, the master switch gene for sex determination is expressed for a limited period during the early embryonic stage. To increase our understanding of the sex determination mechanism in Bombyx mori, it is important to understand when sex ...
Fugaku Aoki +2 more
core +1 more source