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Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b
Science, 2020How egg temperature sets sex In many reptiles, sex is determined by nest temperature during egg incubation. Temperature regulates the expression of an epigenetic modifier gene called Kdm6b, which is responsible for testis development.
C. Weber +6 more
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Journal of Forensic and Legal Medicine, 2019
A deep learning artificial neural network was adapted to the task of sex determination of skeletal remains. The neural network was trained on images of 900 skulls virtually reconstructed from hospital CT scans.
J. Bewes +4 more
semanticscholar +1 more source
A deep learning artificial neural network was adapted to the task of sex determination of skeletal remains. The neural network was trained on images of 900 skulls virtually reconstructed from hospital CT scans.
J. Bewes +4 more
semanticscholar +1 more source
Sex determination and sex reversal
Current Opinion in Genetics & Development, 2006Sex determination in mammals is based on a genetic cascade that controls the fate of the gonads. Gonads will then direct the establishment of phenotypic sex through the production of hormones. Different types of sex reversal are expected to occur if mutations disrupt one of the three steps of gonadal differentiation: formation of the gonadal primordia,
G. Camerino +3 more
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Sex chromosomes and sex determination in reptiles
Current Opinion in Genetics & Development, 2005Reptiles occupy a crucial position with respect to vertebrate phylogeny, having roamed the earth for more than 300 million years and given rise to both birds and mammals. To date, this group has been largely ignored by contemporary genomics technologies, although the green anole lizard was recently recommended for whole genome sequencing.
William S, Modi, David, Crews
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Forensic Science, Medicine and Pathology, 2006
Determing the sex of a give DNA sample can provide criminal investigators with useful intelligence and can aid the identification of missing persons and disaster victims. Polymerase chain reaction-based systems that amplify regions of the am elogenin gene have become the method of choice for sex determination of biological samples.
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Determing the sex of a give DNA sample can provide criminal investigators with useful intelligence and can aid the identification of missing persons and disaster victims. Polymerase chain reaction-based systems that amplify regions of the am elogenin gene have become the method of choice for sex determination of biological samples.
openaire +2 more sources
Human Molecular Genetics, 1994
The cloning of the 'testis determining gene', SRY, promised a revolution in the understanding of sex determination in humans. The failure to isolate further genes involved in sex determination has been a disappointment. The biology of SRY, however, has kept the field exciting. The discoveries of sex reversing SRY mutations with variable penetrance, but
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The cloning of the 'testis determining gene', SRY, promised a revolution in the understanding of sex determination in humans. The failure to isolate further genes involved in sex determination has been a disappointment. The biology of SRY, however, has kept the field exciting. The discoveries of sex reversing SRY mutations with variable penetrance, but
openaire +2 more sources
Sex Chromosomes and Sex Determination in Lepidoptera
Sexual Development, 2007The speciose insect order Lepidoptera (moths and butterflies) and their closest relatives, Trichoptera (caddis flies), share a female-heterogametic sex chromosome system. Originally a Z/ZZ (female/male) system, it evolved by chromosome rearrangement to a WZ/ZZ (female/male) system in the most species-rich branch of Lepidoptera, a monophyletic group ...
W, Traut, K, Sahara, F, Marec
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Determination and stability of sex
BioEssays, 2006AbstractHow is the embryonic bipotential gonad regulated to produce either an ovary or a testis? In males, transient early activation of the Y chromosome Sry gene makes both germ cells and soma male. However, in females, available evidence suggests that the process of ovary sex determination may take place independently in the germline and somatic ...
Ottolenghi C +6 more
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Sex Determination: Turning on sex
Current Biology, 1994The orphan nuclear receptor, steroidogenic factor 1, is central to the differentiation of male and female mammalian gonads. It controls the fate of the initially bipotential gonad as well as later male-specific functions.
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Sex Determination and Differentiation
New England Journal of Medicine, 2004This review elucidates the molecular mechanisms of sex determination and sex differentiation with examples from embryology, animal models, and clinical syndromes. Sex reversal, defective masculinization, pseudohermaphroditism, and syndromes involving the gonads and other organs are some of the clinical problems discussed.
David T, MacLaughlin +1 more
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