Results 81 to 90 of about 265,713 (266)
Differential regulation drives plasticity in sex determination gene networks
BMC Evolutionary Biology, 2010 Background Sex determination networks evolve rapidly and have been studied intensely across many species, particularly in insects, thus presenting good models to study the evolutionary plasticity of gene networks.
Seymour Robert M +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Egyptian Journal of Forensic Sciences, 2014 Background: Sex determination of the human skeleton has been studied in forensic and physical anthropology. Long bones have been especially used because of the ease of defining measurements and better preservation.
Iman F. Gaballah +2 more
doaj +1 more source
Molecular analysis of sex determination in sex-reversed and true hermaphroditism.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1997 The SRY (sex region of Y) gene determines testis formation but not all cases of sex reversal in humans can be explained by alterations in this gene. We studied one 46,XY female, four 46,XX males, and nine true hermaphrodites (TH): three with an XY and six with an XX chromosomal constitution. The SRY gene was identified in the XX males and the TH with a
S B, Copelli +6 more
openaire +1 more source
Sex determination by pelvic osteometry using discriminant analysis
Russian Journal of Forensic MedicineBACKGROUND: One of the current challenges of forensic medicine is the sex identification of skeletal remains. Sex determination from isolated bones is considered a particularly difficult task. Consequently, increased attention has been paid to investigating the possibility of sex identification from an isolated pelvis.
Sergey A. Peregoroda +1 more
openaire +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
CYTOGENETIC ANALYSIS OF SEX DETERMINATION IN SPINACIA OLERACEA [PDF]
Genetics, 1962 M, Iizuka, J, Janick
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Sex determination in Uruguayans byodontometric analysis
, 2014 Sex assessment plays an important role in the forensic and bioarchaeological spheres. Teeth are invaluable elements in non-living populations for sex determination, since they commonly resist post-mortem damages and are latent sources of information about dimorphism. Aim: The present study consisted in an odontometric analysis willing to examine sexual
openaire +1 more source