Results 71 to 80 of about 872,357 (264)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A Tale of Two Tails: Peakedness Properties in Inheritance Models of Evolutionary Theory [PDF]

In this paper, we study transmission of traits through generations in multifactorial inheritance models with sex- and time-dependent heritability. We further analyze the implications of these models under heavy-tailedness of traits' distributions.
Rustam Ibragimov
core  

Comparison of cranial sex determination by discriminant analysis and logistic regression

Anthropologischer Anzeiger, 2016
Various methods have been proposed for estimating dimorphism. The objective of this study was to compare sex determination results from cranial measurements using discriminant analysis or logistic regression. The study sample comprised 130 individuals (70 males) of known sex, age, and cause of death from San José cemetery in Granada (Spain ...
Amores Ampuero, Anabel, Alemán, Inmaculada   +1 more
openaire   +4 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Gender Determination using Fingerprint Features [PDF]

, 2008
Several previous studies have investigated the gender difference of the fingerprint features. However, regarding to the statistical significance of such differences, inconsistent results have been obtained. To resolve this problem and to develop a method
Chang, Yung-Hsien, Lin, Chen-Liang, Nagurka, Mark L., Wang, Jen-Feng, Yeh, Chinson, Yen, Chen-Wen   +5 more
core   +1 more source

Nutritional and Defensive Chemistry of Three North American Ash Species: Possible Roles in Host Performance and Preference by Emerald Ash Borer Adults [PDF]

, 2018
Black ash (Fraxinus nigra), green ash (F. pennsylvanica), and white ash (F. americana) are the three most abundant ash species in the northeastern USA.
Chen, Yigen, Poland, Therese M
core   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Determination of Energy and Protein Requirements of Sheep in Indonesia Using a Meta-analytical Approach [PDF]

, 2017
The objective of this study was to determine energy and protein requirements, for both maintenance and gain, of sheep in Indonesia by using a meta-analysis method.
Astuti, D. A. (D), Jayanegara, A. (A), Laconi, E. B. (E), Nahrowi, N. (Nahrowi), Ridla, M. (M), Wiryawan, K. G. (K)   +5 more
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source