Results 81 to 90 of about 283,241 (311)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Sex determination from os sacrum by postmortem CT

, 2012
Sex determination in forensic practice is performed mostly on sexually dimorphic bones, including pelvic bones such as the os sacrum. Postmortem CT scan provides an easy and fast method for depicting and measuring bone structures prior to elaborate ...
Thali, Michael J., Thali, Michael J, Lösch, Sandra, Zech, Wolf Dieter, Hatch, Gary, Zech, Wolf-Dieter, Siegenthaler, Lea   +6 more
core   +1 more source

'They did not have a word': the parental quest to locate a 'true sex' for their intersex children [PDF]

, 2008
Given the paucity of research in this area, the primary aim of this study was to explore how parents of infants with unclear sex at birth made sense of 'intersex'.
Gary Butler, Mandy Stoner, Gough, B., Stoner, M., Julie Alderson, Gough, B, Brendan Gough, Weyman, N., Butler, G., Nicky Weyman, Alderson, J.   +10 more
core   +1 more source

Identification of sex-linked markers and genes in Portuguese oyster (Magallana angulata)

Frontiers in Marine Science
The Portuguese oyster (Magallana angulata) is a valuable aquaculture species with sexual dimorphism in growth and nutritional traits, making it a promising candidate for sex-controlled breeding.
Xiaoyan Zhou, Yue Ning, Jingyi Xie, Yi Han, Chaonan Tang, Caiyuan Su, Qijuan Wan, Qisheng Wu, Xiang Guo, Jianfei Qi, Yizhou Ke, Hui Ge, Mingyi Cai   +12 more
doaj   +1 more source

Sex determination using cheiloscopy and mandibular canine index as a tool in forensic dentistry

Journal of Forensic Science and Medicine, 2018
Identification of a person′s individuality and sex determination are important for legal as well as identification purposes. The aim of the present study was to check the reliability of cheiloscopy and mandibular canine index (MCI) in the determination ...
B Bhagyashree, Prakash Gadodia, Abhishek Singh Nayyar, Namrata N Patil, M P Vinod Kumar, Vinita Murgod, Swati S Paraye   +6 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Sex determination in Aedes aegypti.

, 2011
We proposed an hypothetical model for sex determination in Aedes that is presented here. In this model we hypothesized the existence of two different upstream regulators that we named SR-M and SR-F (SR is for Splicing Regulator, not necessarily an SR ...
SALVEMINI, MARCO, D'AMATO, ROCCO, PETRELLA, VALERIA, SACCONE, GIUSEPPE, POLITO, CATELLO   +4 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Toward a mRNAseq analysis to explore the transcriptome landscapes of Ceratitis capitata sexed early embryos.

, 2011
Sex determination study of Medfly embryos using ...
SALVEMINI, MARCO, PETRELLA, VALERIA, SACCONE, GIUSEPPE, PANE, ATTILIO, Nagaraju J, D’Amato R, POLITO, CATELLO   +6 more
core