Results 101 to 110 of about 3,546,027 (344)

Menarche, pubertal timing and the brain: female-specific patterns of brain maturation beyond age-related development

Biology of Sex Differences
Background Puberty depicts a period of profound and multifactorial changes ranging from social to biological factors. While brain development in youths has been studied mostly from an age perspective, recent evidence suggests that pubertal measures may ...
Nina Gottschewsky, Dominik Kraft, Tobias Kaufmann   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

The association between cannabis use and suicidal behavior in patients with psychiatric disorders: an analysis of sex differences

Biology of Sex Differences, 2018
Background Cannabis is the most commonly used illicit drug. In the general population, its use has been linked to a heightened propensity for suicidal behavior (SB). We hypothesize that this association varies in patients with psychiatric disorders.
Leen Naji, Tea Rosic, Brittany Dennis, Meha Bhatt, Nitika Sanger, Jackie Hudson, Natalia Mouravska, Lehana Thabane, Zainab Samaan   +8 more
doaj   +1 more source

Early Female Hatching is Related to Sex Differences in Biochemical and Hematological Parameters [PDF]

, 2016
T.I. Vicentini, J.B. Matos, Isabel Cristina Boleli   +2 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Gestational saccharin consumption disrupts gut-brain axis glucose homeostasis control in adolescent offspring rats in a sex-dependent manner

Biology of Sex Differences
Background Certain events that occur in early life, such as changes in nutrition, can promote structural and functional modifications in brain development, projecting to either short, medium, and/or long terms, resulting in metabolic programming.
Beatriz Pacheco-Sánchez, Sonia Melgar-Locatelli, Raquel López-Merchán, María José Benítez-Marín, Marta Blasco-Alonso, Ernesto González-Mesa, Rubén Tovar, Pablo Rubio, Juan Suárez, Carlos Sanjuan, Fernando Rodríguez de Fonseca, Francisco Alén, Marialuisa de Ceglia, Patricia Rivera   +13 more
doaj   +1 more source

Association between cannabis use and methadone maintenance treatment outcomes: an investigation into sex differences

Biology of Sex Differences, 2017
Background Cannabis will soon become legalized in Canada, and it is currently unclear how this will impact public health. Methadone maintenance treatment (MMT) is the most common pharmacological treatment for opioid use disorder (OUD), and despite its ...
Laura Zielinski, Meha Bhatt, Nitika Sanger, Carolyn Plater, Andrew Worster, Michael Varenbut, Jeff Daiter, Guillaume Pare, David C. Marsh, Dipika Desai, James MacKillop, Meir Steiner, Stephanie McDermid Vaz, Lehana Thabane, Zainab Samaan   +14 more
doaj   +1 more source

Contribution of Orai1 to Sex-Based Differences in Cardiac Excitation-Contraction Coupling [PDF]

, 2017
Fiona Bartoli, Baptiste Rode, David J. Beech, Ana M. Gómez, Jean‐Pierre Bénitah, Jessica Sabourin   +5 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Psychosocial and clinical characteristics in Takotsubo syndrome

Biology of Sex Differences
Background Takotsubo Syndrome (TTS) is an acute form of heart failure that disproportionately impacts post-menopausal women. The brain-heart connection is considered a pathway for TTS pathophysiology leading to investigations of the role of psychological,
Okezi Obrutu, Yujie Cui, Jenna Maughan, Paul Marano, Janet Wei, Martha Gulati, Marie Lauzon, Romana Herscovici, Chrisandra Shufelt, Natalie Rojas, Benita Tjoe, Thomas Rutledge, C. Noel Bairey Merz   +12 more
doaj   +1 more source