Results 111 to 120 of about 769,508 (312)

Sex determination [PDF]

open access: yes, 2012
Multicellular animals are a diverse lot, with widely varied body plans and lifestyles. One feature they share, however, is a nearly universal reliance on sexual reproduction for species propagation.
Gamble, Tony
core   +1 more source

Allopatric differentiation in the Marcusenius macrolepidotus species complex in southern and eastern Africa: the resurrection of M. pongolensis and M. angolensis, and the description of two new species (Mormyridae, Teleostei) [PDF]

open access: yes, 2007
We critically compared local populations of the bulldog fish, Marcusenius macrolepidotus (Peters 1852), from different watersheds, from the furthest south (28° South, South Africa) to the Equator in Kenya.
Kramer, Bernd   +3 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Comparative RNA-Seq Analysis of Differentially Expressed Genes in the Testis and Ovary of Mudskipper, Boleophthalmus pectinirostris

open access: yesAnimals
Sex determination and differentiation in teleosts are governed by complex genetic regulatory networks that include evolutionarily conserved mechanisms. In this study, we investigated Boleophthalmus pectinirostris, a Gobiidae species lacking heterogametic
He Ma   +7 more
doaj   +1 more source

"Human sex differentiation: From transcription factors to gender" [PDF]

open access: yes, 2000
Amy B. Wiesniewski is an Assistant Professor of Biology at Drake University, Des Moines, Iowa. She can be contacted at amy.wisniewski@drake.eduOver the past decade, knowledge of the genetic control of human sex differentiation has greately expanded our ...
Migeon, Claude J., Wisniewski, Amy B.
core   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Genome-wide analysis of the MADS-box gene family of sea buckthorn (Hippophae rhamnoides ssp. sinensis) and their potential role in floral organ development

open access: yesFrontiers in Plant Science
Sea buckthorn (Hippophae rhamnoides ssp. sinensis) is a deciduous shrub or small tree in the Elaeagnaceae family. It is dioecious, featuring distinct structures in female and male flowers.
Jing Zhao   +6 more
doaj   +1 more source

Geometric morphometric analysis of scapula at cats and dogs [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi
The scapula in quadrupedal mammals is a flat bone that connects the thoracic limb with the trunk above the shoulder joint. For this purpose, scapulae of 34 dogs and 23 cats were modeled using computer tomography.
Zeynep Nilüfer AKÇASIZ   +7 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Administration of mifepristone can induce masculinization and alter the expression of sex-related genes in Takifugu rubripes

open access: yesAquaculture Reports
Fugu (Takifugu rubripes) is a commercially important fish in aquaculture in China, Japan, and Korea. Male fugu are highly prized compared to females because the mature testes are regarded as a delicacy, thus all-male populations are preferred in ...
Rui Gao   +13 more
doaj   +1 more source

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