Results 161 to 170 of about 769,508 (312)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Gonadal Sex Differentiation and Ovarian Organogenesis along the Cortical-Medullary Axis in Mammals. [PDF]

Int J Mol Sci, 2022
Imaimatsu K, Uchida A, Hiramatsu R, Kanai Y.   +3 more
europepmc   +1 more source

Sex differentiated [PDF]

Nature, 1982
openaire   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

The role of ACS genes in sex differentiation of Siraitia grosvenorii revealed by comparative transcriptomic analysis. [PDF]

BMC Plant Biol
Mo C, Qin F, Guo W, Tang Q, Li Z, Pan L, Luo Z, Wang C, Liang R.   +8 more
europepmc   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Rapid and Nondestructive Sex Differentiation of <i>Aedes aegypti</i> Using Infrared Spectroscopy and Discriminant Analysis. [PDF]

ACS Omega
Santos MCD, Viana JLS, Santos GJSS, Gama RA, Câmara ABF, Lima KMG.   +5 more
europepmc   +1 more source

Gonad Ontogeny and Sex Differentiation in a Poeciliid, Gambusia holbrooki: Transition from a Bi- to a Mono-Lobed Organ. [PDF]

Biology (Basel), 2023
Razmi K, Tran NK, Patil JG.
europepmc   +1 more source

Dementia Incidence in Individuals With Parkinson's Disease in the Framingham Heart Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Limited information exists on incident dementia in individuals with Parkinson's disease (PD) in US community‐based samples. We examined cognitive statuses and PD diagnoses of 183 individuals in the Framingham Heart Study (FHS) to establish incident dementia, mortality rates, associations with sex, age at PD onset, and education level.
Joshi Dookhy, Michael Cummings, Eden Price, Yulin Liu, Santiago Gutierrez‐Gomez, Sarah O'Shea, Samuel Frank, Rhoda Au, Ashita S. Gurnani, Ting Fang Alvin Ang, Jesse Mez, Ludy C. Shih   +11 more
wiley   +1 more source

Sex Differentiation and Long-Distance Gene Flow in the Elusive Antarctic Fish <i>Aethotaxis mitopteryx</i>. [PDF]

Ecol Evol
Schiavon L, Desvignes T, Ronco F, Matschiner M, Gastaldi M, Koppetsch T, Schrøder-Nielsen A, Postlethwait JH, Prestanti A, Stranci F, Ceballos SG, Mark FC, Lucassen M, Riginella E, La Mesa M, Papetti C.   +15 more
europepmc   +1 more source