Results 41 to 50 of about 2,361,701 (304)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Between the Urgent and the Emerging: Representations on Sex Education in the Debate for Abortion Legalization in Argentina

open access: yesFrontiers in Sociology, 2021
The aim of this article is to analyse, within the framework of discourse analysis, the social representations that circulated about the sex education in the parliamentary debate on the bill for the Voluntary Interruption of Pregnancy that took place in ...
Gabriel Dvoskin
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Conclusions: Getting real about sex - embedding an embodied sex education in schools [PDF]

open access: yes, 2007
GET REAL ABOUT SEX: The Politics and Practice of Sex Education explores how cultural ideas about gender, sexuality and parenthood play out in the sex and relationship education classroom.
Alldred, P, David, ME
core  

Sex and Gender in Medical Education, and proceedings from the 2015 Sex and Gender Education Summit [PDF]

open access: yes, 2016
The Sex and Gender Medical Education Summit: a roadmap for curricular innovation was a collaborative initiative of the American Medical Women\u27s Association, Laura W.
Casanova, Robert   +8 more
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

De la cure des âmes à l’évangélisation des corps. Le CLER Amour et Famille : classes dominantes et morale sexuelle

open access: yesGenre, Sexualité et Société, 2017
Essentially composed of women from the Catholic fraction of the dominant classes, CLER Amour et Famille works to promote « ecological » methods of fertility regulation.
Gauthier Fradois
doaj   +1 more source

What Is Safe Sex ? Understanding the Need for Sex Education Reform

open access: yes, 2020
Currently, the United States has no standardized requirement for sex education. This has precipitated a large gap in knowledge about safe sex and a lack of consensus in current social and educational policy.
Baker, Julianne
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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