Results 71 to 80 of about 10,199,452 (302)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Okapi, a “fantastinouï” magazine for pre-teens in the spirit of May '68
Strenae, 2018 In 1971, the group Bayard Press brought out a magazine called Okapi for 7 to 12 year-olds. From the first number that came out, what was striking was the way in which the magazine captured the new educational ambitions of the generation of ‘68.
Cécile Boulaire
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Activities of vocational sex equity mini-grants 1982-1983.
, 1983 Title from cover.Contains summaries of mini-grants funded by the Office of Sex Equity, Division of Vocational Education, Ohio Department of Education, during the 1982-83 school year.
core
"Sexuality isn't just about sex": Pre-service teachers' shifting constructs of sexuality education.
, 2009 This paper presents the findings of a three-year study into pre-service (student) teachers, experiences of and beliefs about sexuality education in New Zealand schools.
Sinkinson, MR
core +1 more source
Autonomia do cuidado: interlocução afetivo-sexual com adolescentes no PET-Saúde
Revista Brasileira de Educação MédicaRealizou-se, dentro do Programa de Educação pelo Trabalho para a Saúde (PET-Saúde), uma pesquisa-ação em conjunto com o Centro de Saúde e a Escola Municipal de Glaura, um dos distritos de Ouro Preto/MG, reunindo 123 alunos, entre 11 e 19 anos de idade ...
Tiago Soares Baumfeld +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Incorporation of a sex education program in health care centers in Tehran, Iran
Payesh, 2007 Objective (s): Sexual health is increasingly recognized as an integral part of health. Despite admirable efforts to meet reproductive health needs in Iran, there are as yet no comprehensive sex education programs in this country.
Rafaie Shirpak Kh +6 more
doaj
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source