Results 81 to 90 of about 7,720,871 (361)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Autonomia do cuidado: interlocução afetivo-sexual com adolescentes no PET-Saúde

Revista Brasileira de Educação Médica
Realizou-se, dentro do Programa de Educação pelo Trabalho para a Saúde (PET-Saúde), uma pesquisa-ação em conjunto com o Centro de Saúde e a Escola Municipal de Glaura, um dos distritos de Ouro Preto/MG, reunindo 123 alunos, entre 11 e 19 anos de idade ...
Tiago Soares Baumfeld, Raphael Botelho Sá, Daniela Fernanda de Almeida Santos, Otávio Montovanelli Monteiro, Mariana Benzaquen Ferreira, Edith Márcia Valadares Silva, Mário Augusto Raymundo, Anderson Melo Queiroz, Palmira de Fátima Bonolo   +8 more
doaj   +1 more source

Okapi, a “fantastinouï” magazine for pre-teens in the spirit of May '68

Strenae, 2018
In 1971, the group Bayard Press brought out a magazine called Okapi for 7 to 12 year-olds. From the first number that came out, what was striking was the way in which the magazine captured the new educational ambitions of the generation of ‘68.
Cécile Boulaire
doaj   +1 more source

Diversity in sex and relationship education – limitations and possibilities in Swedish biology textbooks

, 2022
Shortcomings in sex and relationship education (SRE) related to norms and lesbian, gay, bisexual, transgender, queer, intersex, asexuality (LGBTQIA) perspectives have been reported internationally and in Sweden.
Junkala, Hannele, Silfver, Eva, Silfver, Eva,, Berge, Maria, Junkala, Hannele,, Berge, Maria,   +5 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Sexual Knowledge, Sexual Attitudes, and Perceptions and Actualities of Sex Education among Elementary School Parents

Child Health Nursing Research, 2019
Purpose This study was conducted to understand sexual knowledge, sexual attitudes, and the perceptions and actualities of sex education among parents of elementary school children. Methods This is a descriptive study with a sample size of 337.
Hyewon Shin, J. Lee, Ji Young Min
semanticscholar   +1 more source

Cape Town talks about sex workers

, 2000
On Monday 25 September,, as- part of the One City Festival, the Black Arts Collective hosted a debate about sex work. Natasha from SWEAT spoke about the why the government should decriminalize sex work.
Sex Workers’ Education & Advocacy Taskforce (SWEAT)
core  

Impact of a theoretically based sex education programme (SHARE) delivered by teachers on NHS registered conceptions and terminations: final results of cluster randomised trial [PDF]

, 2006
<b>Objective</b>: To assess the impact of a theoretically based sex education programme (SHARE) delivered by teachers compared with conventional education in terms of conceptions and terminations registered by the NHS.
Parkes, A, Wright, D, Henderson, M, Henderson, M., Hart, G., Wight, D, Scott, S, Raab, G.M., Scott, S., Abraham, C, Wight, D., Raab, GM, Raab, G. M., Hart, G, Parkes, A., Abraham, C.   +15 more
core   +1 more source

Educator and staff perspectives on a rights-based sex education for young men in jail and prison in Sweden

, 2023
Young men in jail and prison are vulnerable regarding sexual health and the fulfilment of their sexual rights. As a response to this, the Swedish Association for Sexuality Education (RFSU) has been providing sex education to young, incarcerated men, via ...
Larsdotter, Suzann, Lindroth, Malin, Lemon, Jonas,, Lemon, Jonas, Larsdotter, Suzann,, Lindroth, Malin,   +5 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source