Results 101 to 110 of about 16,852,931 (379)

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Sex Differences in Nonalcoholic Fatty Liver Disease: State of the Art and Identification of Research Gaps

Hepatology, 2019
Despite tremendous research advancements in nonalcoholic fatty liver disease (NAFLD), our understanding of sex differences in NAFLD remains insufficient.
A. Lonardo, F. Nascimbeni, S. Ballestri, D. Fairweather, S. Win, T. Than, M. Abdelmalek, A. Suzuki   +7 more
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Sex Ratio and Sexual Dimorphism in \u3ci\u3eFormica Exsectoides\u3c/i\u3e, the Allegheny Mound Ant (Hymenoptera: Formicidae) [PDF]

, 2018
We excavated 66 mounds from 6 populations of Formica exsectoides in Michigan jack pine, collecting sexual caste pupae for sex ratio estimates and measurement of dimorphism.
Bristow, C. M, Rowe, H. C
core   +2 more sources

DANSPOT: A Multicenter Stepped‐Wedge Cluster‐Randomized Trial of the Reclassification of Acute Myocardial Infarction: Rationale and Study Design

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Cardiac troponins are the preferred biomarkers for the diagnosis of acute myocardial infarction. Although sex‐specific 99th percentile thresholds of troponins are recommended in international guidelines, the clinical effect of their use is ...
Nina Strandkjær, Nicoline Jørgensen, Rasmus Bo Hasselbalch, Jonas Kristensen, Marie Sophie Sander Knudsen, Thilde Olivia Kock, Theis Lange, Matias Greve Lindholm, Niels Eske Bruun, Lene Holmvang, Christian Juhl Terkelsen, Claus Kjær Pedersen, Martin Kirk Christensen, Jens Flensted Lassen, Linda Hilsted, Søren Ladefoged, Mads Nybo, Mustafa Vakur Bor, Morten Dahl, Annebirthe Bo Hansen, Pia Rørbæk Kamstrup, Henning Bundgaard, Christian Torp‐Pedersen, Kasper Karmark Iversen   +23 more
doaj   +1 more source

Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus

Endocrine reviews, 2016
The steep rise of type 2 diabetes mellitus (T2DM) and associated complications go along with mounting evidence of clinically important sex and gender differences.
A. Kautzky-Willer, J. Harreiter, G. Pacini   +2 more
semanticscholar   +1 more source

Sex differences in severity and mortality from COVID-19: are males more vulnerable?

Biology of Sex Differences, 2020
Coronavirus disease 2019 (COVID-19) has shown high infection and mortality rates all over the world, and despite the global efforts, there is so far no specific therapy available for COVID-19.
A. Pradhan, P. Olsson
semanticscholar   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Associations between selected demographic, biological, school environmental and physical education based correlates, and adolescent physical activity

, 2011
The study investigated associations between selected physical activity correlates among 299 adolescents (90 boys, age 12-14 years) from 3 English schools. Physical activity was assessed by self-report and accelerometry. Correlates represented biological,
Fairclough, Stuart J., Hilland, Toni A., Ridgers, Nicola D., Stratton, Gareth   +3 more
core   +1 more source

Prevalencia de abuso sexual en estudiantes y su relación con el consumo de drogas Prevalence of sexual abuse in students and its relationship with drug consumption

Salud Pública de México, 1998
Objetivo. Determinar la prevalencia de abuso sexual en estudiantes de secundaria y preparatoria, hombres y mujeres, de todo el país, así como su relación con el consumo de drogas. Material y métodos.
Luciana Ramos-Lira, Gabriela Saldívar-Hernández, María Elena Medina-Mora, Estela Rojas-Guiot, Jorge Villatoro-Velázquez   +4 more
doaj