Results 131 to 140 of about 3,770,529 (313)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Predictive factors of functional movement screening and physical fitness in university students: the roles of gender, activity level, and sleep duration

Frontiers in Public Health
BackgroundFunctional movement and physical fitness are critical indicators of health and performance in young adults, yet their determinants among university students remain underexplored.ObjectiveThis study examined the predictive roles of gender, age ...
Samir Abdelnaby Shaaban Essa, Mona Metwally El-Sayed, Ayman Mohamed El-Ashry, Mahmoud Abdelwahab Khedr, Amira Abdelhamid Shawky Morsy, Sameer Mohammed Sayyd, Wadee Abdullah Alkuhaili, Osama Ibrahim Abukhaizaran, Raghad Kamal Tarwneh, Boshra Karem Mohamed El-Sayed, Shaimaa Mohamed Amin, Lamiaa Abd El Hakeem Ali Ahmed, Lamiaa Abd El Hakeem Ali Ahmed, El-Saied Abd El-Hamid El-Sayed Salem   +13 more
doaj   +1 more source

Selling Queer Rights: The Commodification of Queer Rights Activism [PDF]

, 2016
With the recent Supreme Court decision to legalize same-sex marriage throughout the country, many have spoken in support of the decision, calling it a massive expansion of civil rights.
Pedroni, Laurence
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Revealing Sex Differences in Hypertensive Urgency Management: Insights From a Tertiary Hospital

The Journal of Clinical Hypertension
Sex differences in hypertensive urgencies (HUs) remain poorly characterized in emergency department (ED) settings. We conducted a retrospective observational study of adult ED visits for hypertensive urgency at a tertiary hospital in Spain between 2018 ...
Grethzel Prado, Carlos Bea, Elena Martínez, Rubén Gómez, David Ruíz, Celia Prades, Alicia Marco, Inma Sauri, María José Forner, Enrique Rodilla, Josep Redon, Fernando Martínez   +11 more
doaj   +1 more source

Demographic and Socio-economic Determinants of Birth Interval Dynamics in Manipur: A Survival Analysis [PDF]

, 2011
The birth interval is a major determinant of levels of fertility in high fertility populations. A house-to-house survey of 1225 women in Manipur, a tiny state in North Eastern India was carried out to investigate birth interval patterns and its ...
Narendra, RK, Singh, Sanajaoba N, Singh, Sharat N   +2 more
core  

Sex Factor in Coronary Artery Disease [PDF]

BMJ, 1956
A, KEYS, W A, THOMAS, K T, LEE
openaire   +2 more sources

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source