Results 1 to 10 of about 21,553 (216)

Sex hormone-binding globulin controls sex-specific lipolytic activity in human abdominal subcutaneous adipocytes. [PDF]

Mol Metab
Regulation of lipid metabolism is fundamental for metabolic health, and adipose tissue is a central component in this process. Adipose tissue differs considerably between women and men in terms of a higher subcutaneous capacity for storage, which is ...
Abildgaard J, Aleliunaite A, Horvath C, Palani N, Henriksen TI, Zhong J, Lorentsen KM, Svenstrup V, Frederiksen H, Juul A, Scheele CC, Nielsen S.   +11 more
europepmc   +3 more sources

Causal Relationship Between Sex Hormone Binding Globulin and Obstetrical Disorders: A Two-Sample Bidirectional Mendelian Randomization Study. [PDF]

Int J Womens Health
Yanqiong Gan,1,2,* Xinlin Tan,2,* Yu Tang,2 Qi Shi,2 Hongbo Qi1 1Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of Obstetrics, The Affiliated ...
Gan Y, Tan X, Tang Y, Shi Q, Qi H.
europepmc   +4 more sources

Association of age and insulin resistance with sex hormone-binding globulin levels in healthy men. [PDF]

Arch Endocrinol Metab
Objective: To evaluate the putative association of age and insulin resistance with sex hormone-binding globulin levels in healthy men. Methods: In total, 136 healthy men without obesity, aged 18 years or older, were included.
Porgere IF, Rocha BM, Escott GM, Silva LCF, Freitas PAC, Satler F, Silveiro SP.   +6 more
europepmc   +3 more sources

Sex hormone-binding globulin and arthritis: a Mendelian randomization study [PDF]

Arthritis Research & Therapy, 2020
Background Sex hormone-binding globulin (SHBG) has been reported to be a risk factor associated with the development of arthritis by previous observational studies more so of three common forms of arthritis: osteoarthritis (OA), rheumatoid arthritis (RA),
Zihao Qu, Jiawei Huang, Fangkun Yang, Jianqiao Hong, Wei Wang, Shigui Yan   +5 more
doaj   +2 more sources

Sex-specific associations of sex hormone binding globulin and risk of bladder cancer. [PDF]

Open Med (Wars)
Males have a three times higher risk of a diagnosis of bladder cancer (Bca) than females. Sex hormone-binding globulin (SHBG) may be associated with Bca risk. However, the sex-specific role of SHBG in Bca remains unclear.
Ou J, Bi H, Zhou H, Zhang Z, Duan P, Yin H, Zhou Z, Xie Z, Tian X, Ye J, Zhang S.   +10 more
europepmc   +2 more sources

The Association of Low Muscle Mass With Serum Sex Hormones and Sex Hormone-Binding Globulin. [PDF]

J Cachexia Sarcopenia Muscle
Background The purpose of this study was to explore the associations of low muscle mass with serum sex hormones and sex hormone‐binding globulin (SHBG) using data from the National Health and Nutrition Examination Survey (NHANES).
Qin H, Jiao W, Liao G.
europepmc   +2 more sources

Genetic Variants Linked with the Concentration of Sex Hormone-Binding Globulin Correlate with Uterine Fibroid Risk. [PDF]

Life (Basel)
In this study we searched for correlations between polymorphic variants that determine sex hormone-binding globulin concentration (SHBGcon) and uterine fibroids (UFs).
Ponomarenko M, Reshetnikov E, Churnosova M, Aristova I, Abramova M, Novakov V, Churnosov V, Polonikov A, Plotnikov D, Churnosov M, Ponomarenko I.   +10 more
europepmc   +2 more sources

New evidence for the effect of type 2 diabetes and glycemic traits on testosterone levels: a two-sample Mendelian randomization study

Frontiers in Endocrinology, 2023
ObjectiveType 2 diabetes mellitus (T2DM) is an endocrine-related disease with an increasing incidence worldwide. Male sexual dysfunction is common in diabetic patients.
Chengyang Jiang, Yuwei Wang, Wenqiang Yang, Xinghai Yang   +3 more
doaj   +1 more source

Long-Term Effects of a Randomised Controlled Trial Comparing High Protein or High Carbohydrate Weight Loss Diets on Testosterone, SHBG, Erectile and Urinary Function in Overweight and Obese Men. [PDF]

PLoS ONE, 2016
INTRODUCTION:Obesity is associated with reduced testosterone and worsened erectile and sexual function in men. Weight loss improves these outcomes.
Lisa J Moran, Grant D Brinkworth, Sean Martin, Thomas P Wycherley, Bronwyn Stuckey, Janna Lutze, Peter M Clifton, Gary A Wittert, Manny Noakes   +8 more
doaj   +1 more source

Circulating Androgen Concentrations and Risk of Incident Heart Failure in Older Men: The Cardiovascular Health Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Circulating androgen concentrations in men decline with age and have been linked to diabetes and atherosclerotic cardiovascular disease (ASCVD). A similar relationship has been reported for low total testosterone and incident heart failure (HF)
Joyce N. Njoroge, William Tressel, Mary L. Biggs, Alvin M. Matsumoto, Nicholas L. Smith, Emily Rosenberg, Calvin H. Hirsch, John S. Gottdiener, Kenneth J. Mukamal, Jorge R. Kizer   +9 more
doaj   +1 more source