Results 11 to 20 of about 3,086,991 (246)

Identification of Sex Hormone-Binding Globulin in the Human Hypothalamus [PDF]

open access: yesNeuroendocrinology, 2005
Gonadal steroids are known to influence hypothalamic functions through both genomic and non-genomic pathways. Sex hormone-binding globulin (SHBG) may act by a non-genomic mechanism independent of classical steroid receptors. Here we describe the immunocytochemical mapping of SHBG-containing neurons and nerve fibers in the human hypothalamus and ...
Herbert, Zsófia   +7 more
openaire   +5 more sources

Genetic effects on serum testosterone and sex hormone-binding globulin in men: a Korean twin and family study

open access: yesAsian Journal of Andrology, 2016
We conducted a community-based cross-sectional study to evaluate the role of genetics in determining the individual difference in total testosterone and sex hormone-binding globulin levels.
Joohon Sung, Yun-Mi Song
doaj   +2 more sources

Sex hormone binding globulin and insulin resistance [PDF]

open access: yesClinical Endocrinology, 2013
SummarySex hormone binding globulin (SHBG) is a glycoprotein composed of two 373‐amino‐acid subunits. The SHBG gene and a promotor region have been identified. The SHBG receptor has yet to be cloned but is known to act through a G‐protein‐linked second‐messenger system following plasma membrane binding.
Wallace, Ian R   +3 more
openaire   +4 more sources

SHBG (sex hormone-binding globulin) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2012
Review on SHBG (sex hormone-binding globulin), with data on DNA, on the protein encoded, and where the gene is implicated.
Fortunati, N, Catalano, MG
openaire   +4 more sources

Association of central obesity with sex hormonebinding globulin: a cross-sectional study of 1166 Chinese men

open access: yesOpen Medicine, 2018
Background Both sex hormone-binding globulin and central obesity have been found to be associated with metabolic and cardiovascular diseases. However, the direct relation between sex hormone-binding globulin and central obesity has not been demonstrated.
Liu Fangwei   +7 more
doaj   +2 more sources

A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone-Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation [PDF]

open access: yes, 2012
Sex hormone-binding globulin (SHBG) is a glycoprotein responsible for the transport and biologic availability of sex steroid hormones, primarily testosterone and estradiol.
Frank H de Jong   +864 more
core   +3 more sources

Circulating Androgen Concentrations and Risk of Incident Heart Failure in Older Men: The Cardiovascular Health Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Circulating androgen concentrations in men decline with age and have been linked to diabetes and atherosclerotic cardiovascular disease (ASCVD). A similar relationship has been reported for low total testosterone and incident heart failure (HF)
Joyce N. Njoroge   +9 more
doaj   +1 more source

Sex-specific and sex-independent steroid-related biomarkers in early second trimester maternal serum associated with autism

open access: yesMolecular Autism, 2023
Background Prenatal exposure to maternal metabolic conditions associated with inflammation and steroid dysregulation has previously been linked to increased autism risk.
Deborah A. Bilder   +6 more
doaj   +1 more source

Avian corticosteroid-binding globulin: biological function and regulatory mechanisms in physiological stress responses

open access: yesFrontiers in Zoology, 2021
Corticosteroid-binding globulin (CBG) is a high-affinity plasma protein that binds glucocorticoids (GCs) and regulates their biological activities. The structural and functional properties of CBG are crucial to understanding the biological actions of GCs
Hai-Yan Lin   +4 more
doaj   +1 more source

Prevalence, Pattern and Predictors for Dyslipidemia of Chinese Women With Polycystic Ovary Syndrome

open access: yesFrontiers in Cardiovascular Medicine, 2021
Objective: To investigate the prevalence, pattern and risk predictors for dyslipidemia among Chinese women with polycystic ovary syndrome (PCOS).Study Design and Methods: A total of 1,000 women diagnosed as PCOS by modified Rotterdam criteria were ...
Xi Luo   +3 more
doaj   +1 more source

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