Results 11 to 20 of about 20,923 (214)
Corticosteroid-binding globulin (CBG) is a high-affinity plasma protein that binds glucocorticoids (GCs) and regulates their biological activities. The structural and functional properties of CBG are crucial to understanding the biological actions of GCs
Hai-Yan Lin +4 more
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Prevalence, Pattern and Predictors for Dyslipidemia of Chinese Women With Polycystic Ovary Syndrome
Objective: To investigate the prevalence, pattern and risk predictors for dyslipidemia among Chinese women with polycystic ovary syndrome (PCOS).Study Design and Methods: A total of 1,000 women diagnosed as PCOS by modified Rotterdam criteria were ...
Xi Luo +3 more
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Sex hormone binding globulin in breast cancer [PDF]
The present study was undertaken to determine the significance of sex hormone binding globulin, the major and specific binding protein for testosterone and estradiol, in breast cancer. Among breast cancer patients, lower serum levels of Sex hormone binding globulin and higher levels of testosterone were observed.
Dayalu, Naik S L +5 more
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We conducted a community-based cross-sectional study to evaluate the role of genetics in determining the individual difference in total testosterone and sex hormone-binding globulin levels.
Joohon Sung, Yun-Mi Song
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Circulating sex steroids and bladder pain sensitivity in dysmenorrhea
Although elevated estradiol levels facilitate chronic pelvic pain in animal models, it remains to be determined whether sex steroid levels are altered in a cross-section of women with chronic pelvic pain (CPP) and those at-risk for developing CPP.
Kevin M Hellman +5 more
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Context Hypogonadism is a common clinical situation in male patients with liver cirrhosis. Objectives The aim of the present study was to evaluate the effects of orthotopic liver transplantation on testosterone, free testosterone and sex hormone ...
Rodrigo NITSCHE +4 more
doaj +1 more source
Sex hormone binding globulin and insulin resistance [PDF]
SummarySex hormone binding globulin (SHBG) is a glycoprotein composed of two 373‐amino‐acid subunits. The SHBG gene and a promotor region have been identified. The SHBG receptor has yet to be cloned but is known to act through a G‐protein‐linked second‐messenger system following plasma membrane binding.
Wallace, Ian R +3 more
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Sex Hormone-Binding Globulin in Children and Adolescents
Sex hormone-binding globulin (SHBG) is a circulating glycoprotein that transports testosterone and other steroids in the blood. Interest in SHBG has escalated in recent years because of its inverse association with obesity and insulin resistance, and because many studies have linked lower circulating levels of SHBG to metabolic syndrome, type 2 ...
Aydin, Banu, Winters, Stephen J.
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Background Both sex hormone-binding globulin and central obesity have been found to be associated with metabolic and cardiovascular diseases. However, the direct relation between sex hormone-binding globulin and central obesity has not been demonstrated.
Liu Fangwei +7 more
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Longitudinal associations between sex hormone-binding globulin and insulin resistance
Purpose: We aimed to investigate the association between SHBG and the homeostatic model assessment of insulin resistance (HOMA-Ir) in men and women in a prospective observational study.
Kristin Ottarsdottir +4 more
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