Results 1 to 10 of about 18,650 (200)

The hepatic lipidome and HNF4α and SHBG expression in human liver [PDF]

open access: yesEndocrine Connections, 2020
Low plasma levels of sex hormone-binding globulin (SHBG) are a marker for obesity, insulin resistance, non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes.
Stephen J Winters   +3 more
doaj   +3 more sources

Is elevated baseline SHBG associated with increased ovulation?

open access: yesGynecological Endocrinology, 2023
Sexual hormone binding globulin (SHBG) is associated with the endocrine and reproductive systems. We aimed to investigate the role of SHBG in the reproductive process. Therefore, we conducted a secondary analysis of the PCOSAct (Polycystic Ovary Syndrome
Xiaoke Wu, Yanhua Han, Mengyi Zhu
exaly   +3 more sources

Features and relationships of metabolic syndrome components in men with androgen deficiency. Part 1. Are body composition parameters, sex hormone levels and blood pressure interrelated?

open access: yesАкушерство, гинекология и репродукция, 2021
Introduction. Currently, a shortage of studies demonstrating the relationship between body composition disorders in men with excess adipose tissue and metabolic syndrome (MS), depending on the level of testosterone, estradiol, sex hormone binding ...
Z. Sh. Pavlova, V. Yu. Grevina
doaj   +1 more source

Primary, secondary and compensated male biochemical hypogonadism in people living with HIV (PLWH): relevance of sex hormone-binding globulin (SHBG) measurement and comparison between liquid chromatography-tandem mass spectrometry (LC-MS/MS) and chemiluminescent immunoassay for sex steroids assay

open access: yesThe Aging Male, 2022
Background Data about classification of hypogonadism and estrogen deficiency in male people living with HIV (PLWH) are scanty. Aim To investigate the prevalence and characterization of biochemical hypogonadism and relative estrogen deficiency in male ...
Sara De Vincentis   +13 more
doaj   +1 more source

Effect of obesity on androgen receptor and androgen levels in the serum of women with infertility in Babylon, Iraq

open access: yesMedical Journal of Babylon, 2023
Background: Infertility is the inability to get pregnant after engaging in unprotected sexual activity for at least a year. Obesity and overweight are terms used to describe abnormal or excessive weight growth that is harmful to one’s health. Objectives:
Zainab Mohammed Mari   +2 more
doaj   +1 more source

Remarks on the Hormonal Background of the Male Equivalent of Polycystic Ovary Syndrome

open access: yesPrague Medical Report, 2021
The hypothesis that the most common female endocrine disease, the polycystic ovarian syndrome (PCOS), has a male equivalent, has recently become more widely accepted.
Luboslav Stárka, Michaela Dušková
doaj   +1 more source

Estradiol induces allosteric coupling and partitioning of sex-hormone-binding globulin monomers among conformational states

open access: yesiScience, 2021
Summary: Sex-hormone-binding globulin (SHBG) regulates the transport and bioavailability of estradiol. The dynamics of estradiol's binding to SHBG are incompletely understood, although it is believed that estradiol binds to each monomer of SHBG dimer ...
Ravi Jasuja   +10 more
doaj   +1 more source

Usefulness of routine assessment of free testosterone for the diagnosis of functional male hypogonadism

open access: yesThe Aging Male, 2022
Objective To investigate whether routine assessment of free testosterone improves the diagnostic accuracy of functional hypogonadism. Methods Total and free testosterone (calculated on SHBG levels) were determined in 188 patients with sexual symptoms and
Paolo Facondo   +5 more
doaj   +1 more source

Sex hormone-binding globulin, androgens and mortality: the KORA-F4 cohort study

open access: yesEndocrine Connections, 2020
Objective: Sex hormone-binding globulin (SHBG) and androgens have been associated with mortality in women and men, but controversy still exists. Our objective was to investigate associations of SHBG and androgens with all-cause a nd cause-specific ...
Florian Schederecker   +8 more
doaj   +1 more source

Characterization and comparison of recombinant full‐length ursine and human sex hormone‐binding globulin

open access: yesFEBS Open Bio, 2022
Sex hormone‐binding globulin (SHBG) regulates the bioavailability of sex steroid hormones in the blood. Levels of SHBG increase markedly in brown bears (Ursus arctos) during hibernation, suggesting that a key regulatory role of this protein is to quench ...
Anne Mette Frøbert   +6 more
doaj   +1 more source

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