Results 31 to 40 of about 19,253 (201)

SHBG concentration in girls during puberty [PDF]

Pediatric Research, 1978
Using a membrane filter method the role of Sexual Hormone Binding Globulin (SHBG) during female sexual development was investigated. Details on the method and values in boys have already been reported. Before puberty there is no sex difference in SBHG levels.
A Attanasio, B Blank, H-G Scheel, K Rager, D Gupta   +4 more
openaire   +1 more source

Genetic polymorphisms are associated with serum levels of sex hormone binding globulin in postmenopausal women

BMC Medical Genetics, 2008
Background Estrogen activity plays a critical role in bone homeostasis. The serum levels of sex hormone binding globulin (SHBG) influence free estrogen levels and activity on target tissues.
Amado José A, García-Unzueta María T, Zarrabeitia María T, Valero Carmen, Riancho José A, González-Macías Jesús   +5 more
doaj   +1 more source

Sex Hormone Binding Globulin Modifies Testosterone Action and Metabolism in Prostate Cancer Cells

International Journal of Endocrinology, 2016
Sex Hormone Binding Globulin (SHBG) is the major serum carrier of sex hormones. However, growing evidence suggests that SHBG is internalised and plays a role in regulating intracellular hormone action.
Huika Li, Thy Pham, Brett C. McWhinney, Jacobus P. Ungerer, Carel J. Pretorius, Derek J. Richard, Robin H. Mortimer, Michael C. d’Emden, Kerry Richard   +8 more
doaj   +1 more source

Human sex hormone-binding globulin does not provide metabolic protection against diet-induced obesity and dysglycemia in mice

Endocrine Connections, 2018
Background: Sex hormone-binding globulin (SHBG) is the main transporter of sex hormones in most vertebrates. Low SHBG levels have been linked to increased risk for diabetes and metabolic syndrome.
Yael Sofer, Nava Nevo, Michal Vechoropoulos, Gabi Shefer, Etty Osher, Nathan Landis, Karen Tordjman, Geoffrey L Hammond, Naftali Stern   +8 more
doaj   +1 more source

SHBG and Insulin Resistance - Nexus revisited

Bioinformation
Sex hormone binding globulin (SHBG) is a liver-synthesized glycoprotein. Low SHBG levels are associated with insulin resistance (IR). Specific single nucleotide polymorphisms (SNPs) in the SHBG gene are linked to IR. Therefore, it is of interest to provide a review on the comprehensive overview for SHBG related to IR.
Dinakaran, Asha, AR, Srinivasan, Rajagambeeram, Reeta, Nanda, Sunil Kumar, Daniel, Mary   +4 more
openaire   +2 more sources

SHBG, Sex Hormones, and Inflammatory Markers in Older Women [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2011
Abstract Context: In premenopausal and older women, high testosterone and estradiol (E2) and low SHBG levels are associated with insulin resistance and diabetes, conditions characterized by low-grade inflammation.
MAGGIO, Marcello Giuseppe, CEDA, Gian Paolo, Lauretani F, Bandinelli S, Corsi AM, Giallauria F, Guralnik JM, Zuliani G, Cattabiani C, Parrino S, Ablondi F, DALL'AGLIO, Elisabetta, CERESINI, Graziano, Basaria S, Ferrucci L.   +14 more
openaire   +5 more sources

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

Associations of Sex-Hormone-Binding Globulin (SHBG) with Non-SHBG-Bound Levels of Testosterone and Estradiol in Independently Living Men [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2005
Results of in vitro experiments indicate that with increasing concentrations of SHBG, testosterone (T) is preferentially bound to SHBG in comparison with estradiol (E2). In these studies, the ratio of non-SHBG-bound E2 (non-SHBG-E2) to non-SHBG-T increased with increasing levels of SHBG. SHBG has consequently been regarded as an estrogen amplifier.
De Ronde, Willem, Van Der Schouw, Yvonne T., Muller, Majon, Grobbee, Diederick E., Gooren, Louis J G, Pols, Huibert A P, De Jong, Frank H.   +6 more
openaire   +2 more sources

Living Together, Loving Apart: Health, Sexuality and Relationships in Middle‐Aged and Older Men in Europe

Andrology, EarlyView.
ABSTRACT Background Over time, family structures have grown more complex, diversifying adult relationships. While research has compared marital, cohabiting and living apart together relationships based on quality and health, less is known about their sexual dynamics.
Clotilde Sparano, Giammarco Alderotti, Giulia Rastrelli, Giovanni Corona, Leen Antonio, Felipe F. Casanueva, Aleksander Giwercman, Thang S. Han, Ilpo T. Huhtaniemi, Chiara Lucchi, Terence O'Neill, Jolanta Słowikowska‐Hilczer, Jos Tournoy, Dirk Vanderschueren, Frederick Wu, Daniele Vignoli, Mario Maggi   +16 more
wiley   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source