Results 111 to 120 of about 60,867 (320)

Influence of hypothyroidism in men on androgenic function

Mìžnarodnij Endokrinologìčnij Žurnal, 2018
Background. The results of modern researches specify the role of thyroid hormones, metabolic imbalance, psychological stress involved in the maintenance of general and hormonal homoeostasis.
T.I. Krytskyi
doaj   +1 more source

Testosterone, Sex Hormone-Binding Globulin and the Metabolic Syndrome in Men: An Individual Participant Data Meta-Analysis of Observational Studies

PLoS ONE, 2014
Background Low total testosterone (TT) and sex hormone-binding globulin (SHBG) concentrations have been associated with the metabolic syndrome (MetS) in men, but the reported strength of association varies considerably. Objectives We aimed to investigate
J. S. Brand, M. Rovers, B. Yeap, Harald J. Schneider, T. Tuomainen, R. Haring, G. Corona, A. Onat, M. Maggio, C. Bouchard, Peter C. Y. Tong, Richard Y. T. Chen, M. Akishita, J. Gietema, M. Gannagé-Yared, A. Undén, A. Hautanen, Nicolai P. Goncharov, P. Kumanov, S. A. Chubb, Osvaldo P. Almeida, H. Wittchen, J. Klotsche, H. Wallaschofski, H. Völzke, J. Kauhanen, J. Salonen, L. Ferrucci, Y. T. van der Schouw   +28 more
semanticscholar   +1 more source

Disintegrin‐Like and Metalloprotease With Thrombospondin Type 1 Repeat Motifs 13 (ADAMTS13) Activity in 40 Healthy Dogs

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Background In humans, deficiency of a disintegrin‐like and metalloprotease with thrombospondin type 1 motifs, number 13 (ADAMTS13), a von Willebrand factor (vWF) cleaving protease, is an underlying mechanism for thrombosis. The role of ADAMTS13 in canine thromboembolic disease is largely unknown.
Ashley R. Wilkinson, Priscila Beatriz da Silva Serpa, S. Michelle Todd   +2 more
wiley   +1 more source

Effect of Moderate-Intensity Aerobic Training on Some Hormonal and Metabolic Factors Associated With Breast Cancer in Overweight Postmenopausal Women

Sālmand, 2019
Objectives  Obesity is directly associated with an increased risk of breast cancer in postmenopausal women. The current study aimed to examine the effect of aerobic training at moderate intensity on some biomarkers of breast cancer in overweight ...
Mahnaz Khoramjah, Davood Khorshidi, Mohammad Karimi   +2 more
doaj  

Resting Cerebrovascular Haemodynamics and Dynamic Assessment of Cerebrovascular Function in Polycystic Ovary Syndrome

Clinical Endocrinology, Volume 104, Issue 3, Page 245-254, March 2026.
ABSTRACT Objective Despite an increased cerebrovascular disease risk, the impact of Polycystic Ovary Syndrome (PCOS) on cerebrovascular haemodynamics and function is unknown. This study characterised cerebrovascular haemodynamics and function in women with PCOS versus healthy controls. Design Case‐control study.
Cory T. Richards, Thomas D. Griffiths, Zoe H. Adams, Melissa E. Wright, Saajan Davies, Jack S. Talbot, Lauren Broad‐Thomas, Diego García Esteban, Jessica J. Steventon, Patrice Brassard, Kevin Murphy, Philip E. James, D. Aled Rees, Rachel N. Lord   +13 more
wiley   +1 more source

Elevated Total Testosterone Level in an Adult with Erectile Dysfunction

Nepalese Medical Journal, 2019
Erectile dysfunction affects a growing number of men with a significant impact on social function. The cause may be medical and psychological both. Of many risk factors for erectile dysfunction, hyperthyroidism can lead to increased total testosterone by
Vivek Pant, Devish Pyakurel, Keyoor Gautam, Santosh Pradhan, Abha Shrestha   +4 more
doaj   +1 more source

Testosterone deficiency in the adult males [PDF]

, 2012
Testosterone deficiency leads to multiple problems but can be difficult to diagnose.
Cachia, Mario J.
core  

A multipart phase 1 study of the safety, pharmacodynamics and pharmacokinetics of ALG‐055009, a novel thyroid hormone receptor beta (THR‐β) agonist for metabolic dysfunction‐associated steatohepatitis (MASH), in healthy participants

Clinical Pharmacology in Drug Development, Volume 15, Issue 2, February 2026.
Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi, Benedetta Massetto, Megan Fitzgerald, Kha Le, Stanley Wang, Ifong Kan‐Eng, Meenakshi Venkatraman, Naqvi Mohammad, Lawrence Blatt, Tse‐I Lin, Sushmita M. Chanda, John Fry   +11 more
wiley   +1 more source

A computational model of the hypothalamic - pituitary - gonadal axis in female fathead minnows (Pimephales promelas) exposed to 17α-ethynylestradiol and 17β-trenbolone [PDF]

, 2011
© 2011 Li et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Ankley, GT, Armstrong, B, Brian, JV, Denslow, ND, Jensen, KM, Kostich, M, Kroll, KJ, Lazorchak, JM, Li, Z, Orlando, EF, Sepúlveda, MS, Villeneuve, DL, Watanabe, KH   +12 more
core   +7 more sources

Circulating Profiles of the Bile Acid Metabolomics in Patients With Polycystic Ovary Syndrome Treated With Metformin or Canagliflozin

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 2, February 2026.
ABSTRACT Objective Bile acids are indispensable modulators in the development of polycystic ovary syndrome (PCOS). Our previous study identified that metformin and canagliflozin have similar efficacy in patients with PCOS combined with insulin resistance (IR).
Qi Yan, Meili Cai, Nan Wang, Wenhao Wu, Hua Zhang, Yikun Zhu, Jing Luo, Manna Zhang, Jin Li   +8 more
wiley   +1 more source