Results 21 to 30 of about 21,553 (216)

Gynaecomastia as the initial presentation of thyrotoxicosis

Indian Journal of Endocrinology and Metabolism, 2012
Gynaecomastia is a well-recognized manifestation of thyrotoxicosis occurring in a widely variable percentage. Some studies have reported the percentage to be high as 40% while others report it being around 10%.
Triranjan Sanyal, Deep Dutta, K S Shivprasad, Sujoy Ghosh, Satinath Mukhopadhyay, Subhankar Chowdhury   +5 more
doaj   +1 more source

Association of sex hormone-binding globulin gene polymorphism and sex hormone-binding globulin levels in postmenopausal women in relation to type 2 diabetes mellitus – A case–Control study

Biomedical and Biotechnology Research Journal, 2023
Background: In women, menopause constitutes the end of a fertile life as a result of ovarian aging. It is characterized by a significant decrease in estrogen concentration along with the change in the body weight, altered distribution of adipose tissue ...
Priya Alva, N Suchetha Kumari, Adithi Bhandary, Lakshmi Manjeera, Neetha Nandan   +4 more
doaj   +1 more source

Associations of sex hormone-binding globulin and testosterone with diabetes among men and women (the Saku Diabetes study): a case control study

Cardiovascular Diabetology, 2012
Background Sex hormone-binding globulin (SHBG) levels and sex hormones have been implicated in the pathogenesis of type 2 diabetes and cardiovascular diseases.
Goto Atsushi, Morita Akemi, Goto Maki, Sasaki Satoshi, Miyachi Motohiko, Aiba Naomi, Terauchi Yasuo, Noda Mitsuhiko, Watanabe Shaw   +8 more
doaj   +1 more source

Bioavailable testosterone is associated with symptoms of depression in adult men

Journal of International Medical Research, 2020
Objective This study aimed to determine the relationship between serum testosterone levels and depressive symptoms in an adult male population. Methods We conducted a cross-sectional study of 1166 male participants from Zunyi, Guizhou, China.
Zhongbao Chen, Xubo Shen, Kunming Tian, Yijun Liu, Shimin Xiong, Qin Yu, Lulu Dai, Yongjun Shi, Renjuan Zhang, Rong Zeng, Qiyou Wan, Chengliang Xiong, Yuanzhong Zhou   +12 more
doaj   +1 more source

The Free Hormone Hypothesis: When, Why, and How to Measure the Free Hormone Levels to Assess Vitamin D, Thyroid, Sex Hormone, and Cortisol Status

JBMR Plus, 2021
The free hormone hypothesis postulates that only the nonbound fraction (the free fraction) of hormones that otherwise circulate in blood bound to their carrier proteins is able to enter cells and exert biologic effects.
Daniel D Bikle
doaj   +1 more source

Sex-Hormone-Binding Globulin Gene Polymorphisms and Breast Cancer Risk in Caucasian Women of Russia. [PDF]

Int J Mol Sci
Ponomarenko I, Pasenov K, Churnosova M, Sorokina I, Aristova I, Churnosov V, Ponomarenko M, Reshetnikov E, Churnosov M.   +8 more
europepmc   +3 more sources

The association of vitamin D, semen parameters, and reproductive hormones with male infertility: A cross-sectional study

International Journal of Reproductive BioMedicine, 2022
Background: The prevalence of vitamin D deficiency and male infertility is high in Iran. Objective: The present research aimed to examine the association between serum vitamin D [25(OH)D], parameters of semen including semen volume, sperm count, motility
Leila Maghsoumi-Norouzabad, Maryam Labibzadeh, Ahmad Zare Javid, Seyed Ahmad Hosseini, Gholam Abbas Kaydani, Maryam Dastoorpur   +5 more
doaj   +1 more source

The relationship between Components of Metabolic Syndrome and Plasma Level of Sex Hormone-Binding Globulin

European Journal of Translational Myology, 2019
Plasma concentration of sex hormone-binding globulin (SHBG), as an androgen binding protein, is impressed by many physiological and environmental factors.
Amin Alinezhad, Fatemeh Jafari
doaj   +1 more source

Protein S Enhances the Phagocytosis of Phosphatidylserine‐Exposing Erythrocytes: Implications in Sickle Cell Disease

American Journal of Hematology, EarlyView.
ABSTRACT The major anticoagulant Protein S (PROS1) also contributes to the phagocytosis of apoptotic cells by bridging exposed phosphatidylserine (PtdSer) to the MerTK receptor on macrophages (efferocytosis). Whether PROS1 is involved in the splenic clearance of PtdSer‐positive senescent and altered erythrocytes such as erythrocyte ghosts (eryghosts ...
Claire Auditeau, Aurélie Fricot, Raphaël Gauthier, Abdoulaye Sissoko, Zeynep Cacan, Céline Gounou, Laure Joseph, Sandra Manceau, Slimane Allali, Michael Dussiot, Mickael Marin, Alexis Lavergne, Mariem Khamari, Sophie Moog, Elsa Bianchini, Laetitia Claer, Sandrine Laurance, Valentine Brousse, Sébastien Eymieux, Philippe Roingeard, Pascal Amireault, Thiago Trovati Maciel, Alain Brisson, Pierre Buffet, François Saller, Delphine Borgel, Camille Roussel   +26 more
wiley   +1 more source

Pharmacokinetics, Tolerability, and Biomarker Profile of the Neurokinin 3 Receptor Antagonist Fezolinetant in Healthy Japanese Individuals: A 2‐Part, Randomized, Phase 1 Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This 2‐part, randomized, placebo‐controlled, double‐blind, Phase 1 study analyzed the pharmacokinetics, safety, and biomarker profile of fezolinetant in healthy Japanese individuals. Part 1: male participants received single doses of placebo or fezolinetant 15 or 60 mg.
Akira Koibuchi, Megumi Iwai, Kanji Komatsu, Kentaro Kuroishi, Mai Shibata, Masako Saito, Jace Nielsen, Jiayin Huang, Shunji Matsuki   +8 more
wiley   +1 more source