Results 101 to 110 of about 3,086,890 (203)

Sex hormone-binding globulin may explain sex differences for glucose homeostasis and incidence of type 2 diabetes: the KORA study. [PDF]

Research has indicated that sex hormone-binding globulin (SHBG) is associated with glucose homeostasis and may play a role in the etiology of type 2 diabetes (T2D).
Muka, Taulant, Rathmann, Wolfgang, Adamski, Jerzy, Zeller, Tanja, Bano, Arjola, Raeisi-Dehkordi, Hamidreza, van der Schouw, Yvonne T., van der Schouw, Yvonne T, Thorand, Barbara, Nano, Jana, Amiri, Mojgan   +10 more
core   +2 more sources

Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat [PDF]

, 2002
Earlier studies at our laboratory indicated that several hydroxylated polychlorinated biphenyls (OH-PCBs) detected in human blood could specifically inhibit thyroxine (T4) transport by competitive binding to the thyroid hormone transport protein ...
Bergman, A., Berg, J.J.J., van den, van den Berg, J.H.J., Meerts, I.A.T.M., Weijers, B.M., van den Berg, J.J.J., Brouwer, A., Assink, Y., Cenijn, P.H., Berg, J.H.J. van den, Koeman, J.H., Assin, Y.   +11 more
core   +2 more sources

Modulation of sebocyte function in acne: A pathway‐inclusive review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis, Apostolos Pappas, Katja Martin, Mauro Picardo   +3 more
wiley   +1 more source

Dynamics of Kidney Calcium and Phosphorus Mineral Handling in Laying Hens During the Transition to Egg Production

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT The transition from immature pullets to sexually mature female chickens is accompanied by pronounced structural and functional modifications. This is accompanied by coordinated changes in hormonal and metabolic pathways that primarily regulate reproduction, nutrient utilization, and mineral homeostasis to compensate for temporary imbalances ...
Henry Reyer, Michael Oster, Hiba Qasir, Siriluck Ponsuksili, Vera Sommerfeld, Markus Rodehutscord, Klaus Wimmers   +6 more
wiley   +1 more source

Crude association between indicators of body size, sex-steroid hormones, sex-hormone binding globulin, and insulin-like growth factor components among participants age < 50 years.

, 2015
Crude association between indicators of body size, sex-steroid hormones, sex-hormone binding globulin, and insulin-like growth factor components among participants age < 50 years.
Jennifer S. Smith (283828), Erline E. Miller (732444), Qiong Wang (117288), Li Liu (75607), Jing Zhang (23775), Jia-yuan Li (5660839), Lauren E. McCullough (640363), Hui Li (32376)   +7 more
core   +1 more source

POSTPRANDIAL TRIGLYCERIDE AND TESTOSTERONE IN WOMEN WITH CARDIOVASCULAR DISEASES

The Iraqi Journal of Medical Sciences, 2016
Background:High androgen levels may increase cardiovascular disease (CVD) risk in women through adverse effects on lipids, blood pressure, and glucose metabolism. Lipid abnormalitiesare often found in women with CVD.
Shaymaa Z. Al-Saedi, Ghassan A. Al-Shamma, Hashim M. Hashim   +2 more
doaj   +4 more sources

Preclinical Target Animal Safety Evaluation of Veterinary Monoclonal Antibodies: Principles, Methods, and Interpretation

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Monoclonal antibodies (mAbs) represent a rapidly expanding pharmaceutical class in veterinary medicine, with several products now authorized for use in dogs and cats. Limited published articles and veterinarian exposure to the principles of drug development present challenges in interpreting published safety evaluations that inform product ...
Adam Werts, Matthew Kuhn, Lauren Bessey, Alicia Braxton Hickman, Emily Chory, John Mitchell, Kirby Pasloske   +6 more
wiley   +1 more source

Sex hormone-binding globulin levels predict insulin sensitivity, disposition index, and cardiovascular risk during puberty

, 2009
Early puberty is associated with increased risk of subsequent cardiovascular disease. Low sex hormone-binding globulin (SHBG) levels are a feature of early puberty and of conditions associated with increased cardiovascular risk.
Aksglaede, Lise, Munch-Andersen, Thor, Petersen, Joergen Holm, Juul, Anders, Aachmann-Andersen, Niels Jacob, Hilsted, Linda, Sørensen, Kaspar, Helge, Jørn Wulff   +7 more
core   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

Summarizing the Experiences of Individuals Who Have Obesity or Larger Bodies Seeking Fertility Care: A Scoping Review

Obesity Reviews, EarlyView.
ABSTRACT Females who have larger bodies or obesity may be at an increased risk for experiencing infertility. Problematically, both weight or body size and infertility are stigmatized, harming quality of care. We conducted a scoping review to understand the lived experiences of patients who may be subjected to intersecting stigmas of weight and ...
Brooke J. Hebert, Hanna Randhawa, Virginie Blanchette, Kristi B. Adamo, Angela Alberga, Jean‐Patrice Baillargeon, Marilou Côté, Julia Craig, Ariadne Daniel, Liz Dennett, Nicola Heslehurst, Sarah Nutter, Ian Patton, Helena Piccinini‐Vallis, Ximena Ramos Salas, Katie Wadden, Taniya S. Nagpal   +16 more
wiley   +1 more source