Results 261 to 270 of about 1,999,776 (401)

The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches

ESC Heart Failure, EarlyView.
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori, Sergio Davinelli, Armando Ferrera, Alessandro Medoro, Carlo Barsali, Allegra Battistoni, Maurizio Volterrani, Massimo Volpe, Luciano Saso, Speranza Rubattu   +9 more
wiley   +1 more source

The association between polypharmacy and mortality in patients with heart failure: Results from the PULSE dataset

ESC Heart Failure, EarlyView.
A study of 660 heart failure patients (mean age 76.1) found that polypharmacy was common, with only 5% discharged without it, and 60% had died by the end of a median 2.9‐year follow‐up. In patients with heart failure with reduced ejection fraction (HFrEF), hyperpolypharmacy was associated with significantly higher mortality, while in those with ...
Janine Beezer, Andrew L. Clark, Adam Todd, Andrew Kingston, Andrew Husband   +4 more
wiley   +1 more source

Mental Health Impact of Massage and Massage Therapy for Survivors of Domestic and Family Violence and/or Sexual Abuse: A Scoping Review. [PDF]

Int J Ther Massage Bodywork
DiPronio S, Fogarty S.
europepmc   +1 more source

Atrial cardiomyopathy: From healthy atria to atrial failure. A clinical consensus statement of the Heart Failure Association of the ESC

European Journal of Heart Failure, EarlyView.
The diagnosis of atrial cardiomyopathy (AtCM) requires electrical atrial dysfunction, with evidence of either mechanical atrial dysfunction, atrial enlargement, or excessive atrial fibrosis. The diagnostic cut‐points presented are for standard electrocardiogram and echocardiogram studies (see Figure 1 for further detail).
Jerremy Weerts, Otilia Țica, Julia Aranyo, Christian Basile, Angelina Borizanova‐Petkova, Josip Andjelo Borovac, Massimiliano Camilli, Martin Eichenlaub, Emiliano Fiori, Tim Van Loon, Coenraad Withaar, Diana Zakarkaitė, Matthias D. Zink, Marianna Adamo, Alberto Aimo, Elena Arbelo, Felipe Bisbal Van Bylen, Dimitrios T. Farmakis, Dobromir Dobrev, Jelena Čelutkienė, Michael Böhm, Andrew Coats, Marco Metra, Giuseppe Rosano, Frank Ruschitzka, Antoni Bayes‐Genis, Dipak Kotecha   +26 more
wiley   +1 more source

"I Had To Be Brave": Unveiling the Remarkable Resilience of Children Who Experienced Sexual Abuse. [PDF]

J Child Adolesc Trauma
van der Walt C, Mawila-Chauke D.
europepmc   +1 more source

European Journal of Heart Failure expert consensus statement on transcatheter treatment of mitral regurgitation in heart failure

European Journal of Heart Failure, EarlyView.
The patient with SMR: From diagnostic assessment to treatment. Secondary mitral regurgitation (SMR) is highly prevalent in patients with heart failure (HF), associated with poor prognosis, and its treatment is typically preceded by implementing pharmacotherapy for HF as well as cardiac resynchronization therapy.
Christos Iliadis, Marianna Adamo, Volker Rudolph, Nicole Karam, Ralph Stephan von Bardeleben, Stefan D. Anker, Victoria Delgado, Jörg Hausleiter, Hannah Kempton, Marco Metra, Michael Böhm, Stephan Baldus   +11 more
wiley   +1 more source

Enhancing nursing and other healthcare professionals' knowledge of childhood sexual abuse through self-assessment: A realist review. [PDF]

Cochrane Evid Synth Methods
Adisa O, Tyrrell K, Allen K.
europepmc   +1 more source

Febrile status epilepticus and epileptogenesis: The FEBSTAT study

Epilepsia Open, EarlyView.
Abstract The multicenter FEBSTAT study (Consequences of Prolonged Febrile Seizures in Childhood: https://grantome.com/grant/NIH/R37‐NS043209‐12; PI S. Shinnar) examined the outcome of febrile status epilepticus (FSE) in over 200 prospectively enrolled infants, with many followed for 10 years after FSE.
Darrell V. Lewis, Douglas R. Nordli Jr., Douglas R. Nordli III, Shlomo Shinnar, Stephen Chan, Jacqueline A. Bello, L. Matthew Frank, James Voyvodic, William Gallentine, Syndi Seinfeld, Yoshimi Sogawa, Erica Weiss, David Masur, Yuan Xu, Solomon L. Moshé   +14 more
wiley   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Carotid intima‐media thickness may be an early biomarker for cardiovascular risk in patients treated with ketogenic dietary therapy

Epilepsia Open, EarlyView.
Abstract Objective To assess early signs of atherosclerosis following long‐term treatment with the ketogenic diet therapy due to concerns regarding the impact of this low‐carbohydrate, high‐fat diet on cardiovascular health. Method In this cohort study, 28 patients aged 6 to 49 years who had been treated with ketogenic diet therapy for more than five ...
Kathrine C. Haavardsholm, Mahtab Zamani, Mona Skjelland, Anette Ramm‐Pettersen, Karolina Skagen   +4 more
wiley   +1 more source